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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
protoporphyrin IX accumulation
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "protoporphyrin IX accumulation" in MCE Product Catalog:
4
Research Areas:
Pyridoxal isonicotinoyl hydrazone is an orally active and lipophilic iron-specific chelator that acts as a non-competitive inhibitor of ferrochelatase (FECH) by binding iron ions. Pyridoxal isonicotinoyl hydrazone disrupts heme biosynthesis, leading to reduced FECH stability and increased protoporphyrin IX (PPIX) accumulation. Pyridoxal isonicotinoyl hydrazone is promising for research of iron-overload diseases (e.g., β-thalassemia) .
Target:
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Acifluorfen, a protoporphyrinogen oxidase (PROTOX) inhibitor herbicide, promotes the accumulation of protoporphyrin IX (PPIX), and induces tumors in the rodent liver. Acifluorfen causes strong photooxidative destruction of pigments and lipids in sensitive plant species .
Synonyms: V-53482
Research Areas:
Flumioxazin (V-53482) is a protoporphyrinogen IX oxidase (PPO) inhibitor with a rat target IC50 of 4.58 nM. Flumioxazin is found in its biological sources and is used for pre-emergence control of dicotyledonous weeds in soybean and peanut. Flumioxazin inhibits protoporphyrinogen oxidase, blocking chlorophyll and heme biosynthesis, leading to protoporphyrin IX accumulation, oxidative stress, membrane damage, and cell death. Flumioxazin is used in research on weed control .
Synonyms: Benzyl-ALA hydrochloride
Research Areas:
5-ALA benzyl ester hydrochloride (Benzyl-ALA hydrochloride) is a protoporphyrin precursor used as a photodetection agent. 5-ALA benzyl ester hydrochloride induces protoporphyrin IX (PPIX) accumulation in colon carcinoma cell lines .
Cat. No.: HY-118985
CAS No.: 62476-59-9
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Acifluorfen sodium, a protoporphyrinogen oxidase (PROTOX) inhibitor herbicide, promotes the accumulation of protoporphyrin IX (PPIX), and induces tumors in the rodent liver. Acifluorfen sodium causes strong photooxidative destruction of pigments and lipids in sensitive plant species .
Cat. No.: HY-128075R
CAS No.: 50594-66-6
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Acifluorfen (Standard) is the analytical standard of Acifluorfen. This product is intended for research and analytical applications. Acifluorfen, a protoporphyrinogen oxidase (PROTOX) inhibitor herbicide, promotes the accumulation of protoporphyrin IX (PPIX), and induces tumors in the rodent liver. Acifluorfen causes strong photooxidative destruction of pigments and lipids in sensitive plant species .
Cat. No.: HY-114507R
CAS No.: 103361-09-7
Synonyms: V-53482 (Standard)
Research Areas:
Flumioxazin (Standard) (V-53482 (Standard)) is the analytical standard of Flumioxazin (HY-114507). This product is intended for research and analytical applications. Flumioxazin (V-53482) is a protoporphyrinogen IX oxidase (PPO) inhibitor with a rat target IC50 of 4.58 nM. Flumioxazin is found in its biological sources and is used for pre-emergence control of dicotyledonous weeds in soybean and peanut. Flumioxazin inhibits protoporphyrinogen oxidase, blocking chlorophyll and heme biosynthesis, leading to protoporphyrin IX accumulation, oxidative stress, membrane damage, and cell death. Flumioxazin is used in research on weed control .
Cat. No.: HY-W747602
CAS No.: 142891-20-1
Research Areas:
Cinidon-ethyl is a herbicide . Cinidon-ethyl blocks the conversion of protoporphyrinogen IX to protoporphyrin IX, disrupts the tetrapyrrole biosynthetic process, and leads to the accumulation of protoporphyrin IX and the generation of ROS. Cinidon-ethyl induces the expression of peroxidase and defense-related genes in wheat. Cinidon-ethyl triggers light-dependent ethylene and ethane release, tissue dehydration and necrosis in sensitive broadleaf weeds. Cinidon-ethyl is applicable to research related to the control of broadleaf weeds in wheat fields .
Cat. No.: HY-W747529
CAS No.: 117337-19-6
Fluthiacet-methyl is an isoxazole herbicide and also a protoporphyrinogen oxidase (Protox) inhibitor. Fluthiacet-methyl inhibits chlorophyll biosynthesis in cotyledons of velvetleaf and cotton. Fluthiacet-methyl induces electrolyte leakage in cotyledons of sensitive plants such as velvetleaf and cotton. Fluthiacet-methyl induces the accumulation of protoporphyrin IX in cotton cotyledons .
Cat. No.: HY-183416
CAS No.: 111234-77-6
Research Areas:
M&B 39279 is an inhibitor of protoporphyrinogen oxidase (Protoporphyrinogen Oxidase). M&B 39279 induces protoporphyrin IX accumulation, light-dependent lipid peroxidation, degradation of membranes and organelles, and reduction of photosynthesis. M&B 39279 functions through the mechanism of action of diphenyl ether herbicides, and can be used for studies on PPO inhibition and herbicide mechanisms of action .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
