62476-59-9
62476-59-9
Chemical Structure
Acifluorfen sodium
- CAS No.: 62476-59-9
- Formula:C14H6ClF3NNaO5
- Molecular Weight:383.64
IUPAC Name: sodium 5-(2-chloro-4-(trifluoromethyl)phenoxy)-2-nitrobenzoate
InChIKey: RVULBHWZFCBODE-UHFFFAOYSA-M
SMILES: O=C(O[Na])C1=CC(OC2=CC=C(C(F)(F)F)C=C2Cl)=CC=C1[N+]([O-])=O
Biological Activity: Acifluorfen sodium, a protoporphyrinogen oxidase (PROTOX) inhibitor herbicide, promotes the accumulation of protoporphyrin IX (PPIX), and induces tumors in the rodent liver. Acifluorfen sodium causes strong photooxidative destruction of pigments and lipids in sensitive plant species[1][2].
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Acifluorfen sodium | Acifluorfen sodium, a protoporphyrinogen oxidase (PROTOX) inhibitor herbicide, promotes the accumulation of protoporphyrin IX (PPIX), and induces tumors in the rodent liver. Acifluorfen sodium causes strong photooxidative destruction of pigments and lipids in sensitive plant species. | |||||||||||||||||||||
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References
- [1]. Kuwata K, et al. Involvement of Mouse Constitutive Androstane Receptor in Acifluorfen-Induced Liver Injury and Subsequent Tumor Development. Toxicol Sci. 2016;151(2):271-285. [Content Brief]
- [2]. Hong T, et al. Exposure to acifluorfen induces developmental toxicity in the early life stage of zebrafish. Comp Biochem Physiol C Toxicol Pharmacol. 2024 Jul;281:109909. [Content Brief]
Keywords
