4 Results for "

pyroglutamate amyloid-β

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "pyroglutamate amyloid-β" in MCE Product Catalog:

Art. -Nr.: HY-P99859
CAS. Nr.: 1931944-80-7
Synonyms: LY3002813

Target:  

Amyloid-β

Forschungsgebiete:  

Neurological Disease

Donanemab (LY3002813) is a humanized IgG1 monoclonal antibody directed at an N-terminal pyroglutamate amyloid beta (Aβ) epitope. Donanemab has the potential for early Alzheimer's disease research .
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Art. -Nr.: HY-P4885
CAS. Nr.: 161818-04-8
Synonyms: AβpE3-40
Target:  

Amyloid-β

Forschungsgebiete:  

Neurological Disease

Glp-Amyloid-β (3-40) Peptide (human) (AβpE3-40) is a minor amounts of pyroglutamate-modified isolated from from 24-month-old Amyloid precursor protein (APP) transgenic Mice .
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Art. -Nr.: HY-P4882
CAS. Nr.: 183449-57-2
Target:  

Amyloid-β Tau Protein

Forschungsgebiete:  

Neurological Disease

(Pyr3)-Amyloid β-Protein (3-42) is an N-terminally truncated pyroglutamylated β-amyloid peptide. (Pyr3)-Amyloid β-Protein (3-42) forms stable β-sheet structures across different pH values, co-oligomerizes with Aβ1-42 to form cytotoxic oligomers, induces tau-dependent cytotoxicity and neuronal loss, inhibits hippocampal LTP, and exhibits stronger protease resistance. (Pyr3)-Amyloid β-Protein (3-42) exists in the brain tissues of human Alzheimer's disease patients, correlates with the pathogenesis of Alzheimer's disease, and follows a unique, faster oligomerization pathway. (Pyr3)-Amyloid β-Protein (3-42) can be used in Alzheimer's disease-related research .
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Art. -Nr.: HY-P99859A
CAS. Nr.: 1931944-80-7
Synonyms: LY3002813 (powder)

Target:  

Amyloid-β

Forschungsgebiete:  

Neurological Disease

Donanemab (LY3002813) (powder) is a humanized IgG1 monoclonal antibody directed at an N-terminal pyroglutamate amyloid beta (Aβ) epitope. Donanemab (powder) has the potential for early Alzheimer's disease research .
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