2. Neuronal Signaling
  3. Amyloid-β
  4. Donanemab

Donanemab  (Synonyms: LY3002813)

Cat. No.: HY-P99859 Purity: 96.69%
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Donanemab (LY3002813) is a humanized IgG1 monoclonal antibody directed at an N‐terminal pyroglutamate amyloid beta (Aβ) epitope. Donanemab has the potential for early Alzheimer's disease research.

For research use only. We do not sell to patients.

Donanemab Chemical Structure

Donanemab Chemical Structure

CAS No. : 1931944-80-7

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Description

Donanemab (LY3002813) is a humanized IgG1 monoclonal antibody directed at an N‐terminal pyroglutamate amyloid beta (Aβ) epitope. Donanemab has the potential for early Alzheimer's disease research[1][2].

In Vitro

Donanemab is a humanized IgG1 antibody directed at an N-terminal pyroglutamate Aβ epitope that is present only in established plaques. Donanemab is specific for this epitope and shows no off-target binding to other Aβ species, neurotransmitters, or their receptors[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Donanemab Related Antibodies
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CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Donanemab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation

Purity: 96.69%

COA (231 KB)

Handling Instructions (2659 KB)
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Donanemab Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Donanemab1931944-80-7LY3002813LY 3002813LY-3002813Amyloid-ββ-amyloid peptideAβAbetahumanized IgG1 monoclonal antibodyAlzheimer's diseaseInhibitorinhibitorinhibit

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