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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
sarcolemmal
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "sarcolemmal" in MCE Product Catalog:
10
10 Publications Verification
Synonyms: (±)-Bay K 8644
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Bay K 8644 ((±)-Bay K 8644) is a racemate consisting of two isomers (R)-(+)-Bay-K-8644 and (S)-(-)-Bay-K-8644 . Bay K 8644 is a L-type Ca 2+ channel agonist with an EC50 of 17.3 nM. Bay K 8644 increases Ca 2+ influx through sarcolemmal Ca 2+ channels by increasing the open time of the channel. Bay K 8644 has vasoconstrictive effects .
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Cardiovascular Disease Plants Brassicaceae Disease Research Fields Erysimum cheiranthoides Linn. Steroids
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DPI 201-106 (SDZ 201106) is a cardiotonic agent with a synergistic sarcolemmal and intracellular mechanism of action. DPI 201-106 shows cardioselective modulation of voltage-gated sodium channels (VGSCs) resulting in a positive inotropic effect .
Synonyms: HMR 1098
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Clamikalant sodium (HMR 1098) is an ATP-sensitive potassium (KATP) channel blocker. Clamikalant sodium can be used for the research of arrhythmia .
Cat. No.: HY-10588R
CAS No.: 71145-03-4
Synonyms: (±)-Bay K 8644 (Standard)
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Bay K 8644 (Standard) is the analytical standard of Bay K 8644. This product is intended for research and analytical applications. Bay K 8644 ((±)-Bay K 8644) is a racemate consisting of two isomers (R)-(+)-Bay-K-8644 and (S)-(-)-Bay-K-8644 . Bay K 8644 is a L-type Ca2+ channel agonist with an EC50 of 17.3 nM. Bay K 8644 increases Ca2+ influx through sarcolemmal Ca2+ channels by increasing the open time of the channel. Bay K 8644 has vasoconstrictive effects .
Cat. No.: HY-114252R
CAS No.: 66-28-4
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Cat. No.: HY-P10811
Synonyms: XIP
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Cat. No.: HY-19666R
CAS No.: 97730-95-5
Synonyms: SDZ 201106 (Standard)
Target:
Research Areas:
DPI 201-106 (Standard) is the analytical standard of DPI 201-106. This product is intended for research and analytical applications. DPI 201-106 (SDZ 201106) is a cardiotonic agent with a synergistic sarcolemmal and intracellular mechanism of action. DPI 201-106 shows cardioselective modulation of voltage-gated sodium channels (VGSCs) resulting in a positive inotropic effect .
Cat. No.: HY-183921
CAS No.: 135100-65-1
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SQ 32547 is a dihydropyridine calcium channel inhibitor with antihypertensive and anti-ischemic activities. SQ 32547 modulates sarcolemmal voltage-dependent calcium channels to inhibit calcium influx, and exerts direct anti-ischemic activity by suppressing myocardial contracture formation and reducing lactate dehydrogenase (LDH) release. SQ 32547 can be used in research related to hypertension, angina pectoris and neurogenic inflammation .
Cat. No.: HY-187612
CAS No.: 168620-45-9
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FR-168888 free base is a Na +/H + exchanger (NHE) inhibitor (Ki=6.4 nM) with weak inhibitory activity against Na +/Ca 2+ exchanger and no cardioprotective effects. FR-168888 free base is widely applicable to studies related to reperfusion-induced ventricular arrhythmias .
Cat. No.: HY-N19650
CAS No.: 11024-55-8
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Cat. No.: HY-164295A
CAS No.: 133681-84-2
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U-78517 dihydrochloride, a Trolox (HY-101445) analog, is a potent antioxidant. U-78517 dihydrochloride inhibits DCVC (HY-19717)-induced lipid peroxidation, scavenges DPPH, oxygen- and nitrogen-based free radicals. U-78517 dihydrochloride attenuates hypoxic injury in iaolated cardiac myocytes. U-78517 dihydrochloride can be used for the research of hypoxic injury, cerebral ischemia, and cardiovascular disease .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
