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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
serine/threonine-specific
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "serine/threonine-specific" in MCE Product Catalog:
Cat. No.: HY-170616
CAS No.: 3062848-75-0
Target:
Research Areas:
JH-FK-08 is an inhibitor for the serine/threonine-specific phosphatase calcineurin. JH-FK-08 exhibits antifungal activity that inhibits C. neoformans with MIC80 of 0.8 µg/mL. JH-FK-08 exhibits immunosuppressive activity and inhibits the IL-2 expression with an IC50 of 42.6 nM. JH-FK-08 exhibits anti-infectious activity in mouse models .
Cat. No.: HY-P1873
CAS No.: 150829-21-3
Target:
Research Areas:
Cat. No.: HY-L081
185 compounds
Protein phosphorylation is a key post-translational modification underlying the regulation of many cellular processes. Phosphatases and kinases contribute to the regulation of protein phosphorylation homeostasis in the cell. This reversible regulation of protein phosphorylation is critical for the proper control of a wide range of cellular activities, including cell cycle, proliferation and differentiation, metabolism, cell-cell interactions, etc.
Protein phosphatases have evolved in separate families that are structurally and mechanistically distinct. Based on substrate specificity and functional diversity, protein phosphatases are classified into two superfamilies: Protein serine/threonine phosphatases and Protein tyrosine phosphatases. Ser/Thr phosphatases are metalloenzymes belonging to two major gene families termed PPP (phosphoprotein phosphatase) and PPM (metal-dependent protein phosphatases), whereas protein tyrosine phosphatases (PTPs) belong to distinct classes of enzymes that utilize a phospho-cysteine enzyme intermediate as a part of their catalytic action.
MCE supplies a unique collection of 185 phosphatase inhibitors that mainly targeting protein tyrosine phosphatases (PTPs) and serine/threonine-specific protein phosphatases. MCE Phosphatase Inhibitor Library is a useful tool for phosphatase drug discovery and related research.
Cat. No.: HY-P703602
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PKMYT1; Myt1 Kinase; Protein Kinase, Membrane Associated Tyrosine/threonine 1; PPP1R126; Membrane-Associated Tyrosine- And threonine-specific Cdc2-Inhibitory Kinase; Protein Phosphatase 1, Regulatory Subunit 126; MYT1; Non-specific serine/threonine Protei
Species:
Human
Source:
E. coli
Cat. No.: HY-P702926
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: PKMYT1; Myt1 Kinase; Protein Kinase, Membrane Associated Tyrosine/threonine 1; PPP1R126; Membrane-Associated Tyrosine- And threonine-specific Cdc2-Inhibitory Kinase; Protein Phosphatase 1, Regulatory Subunit 126; MYT1; Non-specific serine/threonine Protein Kinase
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P1873B
Target:
Research Areas:
Cat. No.: HY-P701667
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: DYRK1A; HP86; Prev. DYRK; serine/threonine-specific Protein Kinase; Prev. MNBH; Mnb Protein Kinase Homolog Hp86; Prev. DYRK1; serine/threonine Kinase MNB; Dual specificity Tyrosine-Phosphorylation-Regulated Kinase 1A; MNB/DYRK Protein Kinase; Protein Kina
Species:
Human
Source:
E. coli
Cat. No.: HY-P701668
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: DYRK1A; HP86; Prev. DYRK; serine/threonine-specific Protein Kinase; Prev. MNBH; Mnb Protein Kinase Homolog Hp86; Prev. DYRK1; serine/threonine Kinase MNB; Dual specificity Tyrosine-Phosphorylation-Regulated Kinase 1A; MNB/DYRK Protein Kinase; Protein Kina
Species:
Human
Source:
E. coli
Cat. No.: HY-P71150
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DUSP3; Dual specificity Protein Phosphatase 3; Prev. VHR; serine/threonine specific Protein Phosphatase; Dual specificity Protein Phosphatase VHR; Dual specificity Protein Phosphatase; Vaccinia Virus Phosphatase VH1-Related; Dual specificity Phosphatase 3
Species:
Human
Source:
E. coli
Cat. No.: HY-P703898
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DUSP3; Dual specificity Protein Phosphatase 3; Prev. VHR; serine/threonine specific Protein Phosphatase; Dual specificity Protein Phosphatase VHR; Dual specificity Protein Phosphatase; Vaccinia Virus Phosphatase VH1-Related; Dual specificity Phosphatase 3
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P705939
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: DUSP4; Dual specificity Protein Phosphatase HVH2; Dual specificity Phosphatase 4; Dual specificity Protein Phosphatase 4; MKP-2; VH1 Homologous Phosphatase 2; MAP Kinase Phosphatase 2; MKP2; HVH2; serine/threonine specific Protein Phosphatase; TYP; VH2; M
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
