DUSP3 Protein, Human (sf9)
DUSP3, a dual-specificity phosphatase, preferentially dephosphorylates phosphotyrosines. Its main function involves inactivating ERK1 and ERK2, thereby modulating associated cellular signaling pathways. DUSP3 Protein, Human (sf9) is the recombinant human-derived DUSP3 protein, expressed by Sf9 insect cells, with tag free.
- Species: Human
- Source: Sf9 insect cells
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Biological Activity
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Product Properties
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Biological Activity
DUSP3, a dual-specificity phosphatase, preferentially dephosphorylates phosphotyrosines. Its main function involves inactivating ERK1 and ERK2, thereby modulating associated cellular signaling pathways. DUSP3 Protein, Human (sf9) is the recombinant human-derived DUSP3 protein, expressed by Sf9 insect cells, with tag free.
The DUSP3 protein exhibits dual phosphatase activity, targeting both tyrosine-protein phosphate and serine-protein phosphate, with a notable preference for phosphotyrosines. Its primary function involves the dephosphorylation and subsequent inactivation of ERK1 and ERK2, thereby modulating cellular signaling pathways associated with these kinases.
Technical Parameters
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Species Human
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Source Sf9 insect cells
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Tag Tag Free
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Accession
P51452-1 (N-G&P, M1-P185)
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Gene ID1845
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Protein Length
Full Length
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Synonyms
Dual specificity protein phosphatase 3; DUSP3; Dual specificity protein phosphatase VHR; Vaccinia H1-related phosphatase; VHR
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Predicted Molecular Mass
20.6 kDa
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Molecular Weight
Approximately 21 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
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Purity
≥ 95%, as determined by reducing SDS-PAGE.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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