Search Result
Results for "
sesquiterpenoid
" in MedChemExpress (MCE) Product Catalog:
1
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-N0104
-
Curcumol
Maximum Cited Publications
9 Publications Verification
(-)-Curcumol
|
Apoptosis
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Cancer
|
|
Curcumol ((-)-Curcumol), a bioactive sesquiterpenoid, possesses numerous pharmacological activities like anticancer, antimicrobial, antifungal, antiviral, and antiinflammatory. Curcumol is a potent inducer of apoptosis in numerous cancer cells via targeting key signaling pathways as MAPK/ERK, PI3K/Akt and NF-κB which are generally deregulated in several cancers .
|
-
-
- HY-121262
-
|
Bisabolene; γ-Bisabolene
|
Drug Intermediate
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Infection
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Bisabolene (mixture of isomers) (Bisabolene) is a sesquiterpenoid plant natural product and also a hydrocarbon precursor for various industry-relevant chemicals. Bisabolene (mixture of isomers) serves as an important precursor for the production of industry-relevant chemicals such as biofuels, bioplastics, pharmaceuticals and cosmetics .
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-
-
- HY-N3340
-
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Fungal
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Infection
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Macrocarpal I is a phloroglucinol coupled sesquiterpenoid with antifungal activity. Macrocarpal I against C. glabrata with an IC50 value of 0.75 μg/mL. Macrocarpal I can be isolated from the juvenile leaves of E. maideni .
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-
-
- HY-N8736
-
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Others
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Others
|
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Eicosanyl (E)-caffeate is a sesquiterpenoid isolated from the root of Wikstroemia scytophylla .
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-
-
- HY-N10014
-
|
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Fungal
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Infection
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Bulnesol is a sesquiterpenoid that can be isolated from Salvia dorystaechas. Bulnesol inhibits the activity of Fusarium moniliforme with an EC50 value of 0.6 mg/mL. Bulnesol can be used for the research of fungal infection .
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-
-
- HY-N10321
-
|
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Others
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Others
|
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Kanshone C is a sesquiterpenoid of Nardostachys chinensis roots .
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-
-
- HY-N3337
-
|
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Others
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Others
|
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Macrocarpal L is a Sesquiterpenoids product that can be isolated from the branches of Eucalyptus globulus .
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-
-
- HY-126484
-
|
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Fungal
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Others
|
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Eremofortin B is a sesquiterpenoid compound synthesized by penicillium roqueforti PR Toxin (PRT) .
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-
-
- HY-N1571
-
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Others
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Others
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Pterosin D is a sesquiterpenoid, that can be isolated from aerial plants of P. cretica .
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-
-
- HY-119735
-
|
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Others
|
Cardiovascular Disease
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Curcolone is a sesquiterpenoid that inhibits collagen-induced or arachidonic acid (AA)-induced platelet aggregation .
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-
-
- HY-N8934
-
|
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Others
|
Cancer
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6β-Hydroxytomentosin, a sesquiterpenoid, can be found in flowers of Inula japonica. 6β-Hydroxytomentosin exhibits weak cytotoxicities against A549, SK-OV-3, HepG-2 and HT-29 cell lines .
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-
-
- HY-N16123
-
|
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Parasite
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Infection
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Chloranthalactone C (Compound 43), a lindenane-type sesquiterpenoid, is an antimalarial agent. Chloranthalactone C can be isolated from plant Chloranthus japonicas Sieb. Chloranthalactone C inhibits Chloroquine (HY-17589A)-resistant Plasmodium falciparum strain Dd2 growth. Chloranthalactone C can be used for parasitic infections research .
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-
-
- HY-N10623
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|
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Tyrosinase
|
Cancer
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5-epi-Arvestonate A is a sesquiterpenoid isolated from the whole plants of Seriphidium transiliense. 5-epi-Arvestonate A promotes melanogenic production by activating the transcription of microphthalmia-associated transcription factor (MITF) and tyrosinase family genes. 5-epi-Arvestonate A inhibits the expression of IFN-γ-chemokine through the JAK/STAT signaling pathway in immortalized human keratinocyte (HaCaT) cells .
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-
-
- HY-134572
-
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Others
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Others
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(2S,3S)-Pterosin C is a natural sesquiterpenoid compound .
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-
-
- HY-N3174
-
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Others
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Others
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(2R)-Norpterosin B is a sesquiterpenoid isolated from Pteris semipinnata .
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-
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- HY-N11480
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Others
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Others
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(2E)-Leocarpinolide F (Compound 20), a germacrane-type sesquiterpenoid, can be isolated from Sigesbeckia orientalis .
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-
-
- HY-N7606
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Others
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Others
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(Rac)-β-Chamigrenic acid is a racemate of β-Chamigrenic acid. β-Chamigrenic acid is a sesquiterpenoid isolated from S.chinensis
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-
-
- HY-N12266
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Others
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Others
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12-Hydroxyalbrassitriol is a drimane sesquiterpenoid that can be isolated from Penicillium sp .
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-
-
- HY-N10218
-
|
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Others
|
Inflammation/Immunology
|
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Sterpurol D is a compound of the sterpurane sesquiterpenoid. Sterpurol D significantly inhibits nitric oxide (NO) production .
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-
-
- HY-171795
-
|
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Bacterial
Fungal
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Infection
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Isolubimin is a sesquiterpenoid phytoalexin found in Datura stramonium fruits with antibacterial activity. Isolubimin is promising for research of plant disease caused by fungal infections .
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-
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- HY-N12191
-
|
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HSV
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Others
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Cangorinine E-1 (compound 11) is a dihydroagarofuran derivative of the sesquiterpenoid family. Cangorinine E-1 exhibits weak inhibitory effects on herpes simplex virus type II (HSV) .
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-
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- HY-N10683
-
|
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Others
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Others
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1b-Benzoyl-8a-cinnamoyl-4a,5a-dihydroxydihydroagarofuran is a sesquiterpenoid isolated from the root bark of Tripterygium hypoglaucum containing a benzoyl and a cinnamoyl group .
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-
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- HY-N8103
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Amyloid-β
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Neurological Disease
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Heishuixiecaoline A is a germacrane-type sesquiterpenoid. Heishuixiecaoline A shows protective effect on the neurotoxicity of PC12 cells induced by Aβ25-35 .
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-
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- HY-N8136
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Others
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Others
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Volvalerenic acid A is a germacrane-type sesquiterpenoid that can be found in the roots of Valeriana officinalis var. latifolia .
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-
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- HY-N16131
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|
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Drug Derivative
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Others
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Sydonic acid is a bisabolane-type sesquiterpenoid that can be isolated from the fungus Aspergillus sydowii BTBU20213012, which was obtained from a marine sediment sample in the Western Pacific .
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-
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- HY-N8862
-
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Others
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Inflammation/Immunology
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Anti-inflammatory agent 69 (compound 12), sesquiterpenoid, is an anti-inflammatory agent isolated from the dried flower buds of Tussilago farfara. Anti-inflammatory agent 69 can inhibit the NO production with IC50 value of 24 μM .
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-
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- HY-N3241
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Bacterial
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Infection
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Mucrolidin is an eudesmane-type sesquiterpenoid isolated from aerial parts of homalomena occulta. Mucrolidin exhibits weak antibacterial activities when it compares to Rifampicin (HY-B0272) .
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-
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- HY-N3879
-
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Others
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Others
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Eudesm-4(14)-ene-3α,11-diol (compound 2) is a sesquiterpenoid. Eudesm-4(14)-ene-3α,11-diol can be isolated from Neocallitropsis Pancheri Florin .
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-
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- HY-N5081
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Others
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Cancer
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1αH,5αH-Guaia-6-ene-4β,10β-diol is a sesquiterpenoid derivative identified from Alisma orientale. 1αH,5αH-Guaia-6-ene-4β,10β-diol has anti-cancer activities .
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-
-
- HY-N10458
-
|
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NF-κB
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Inflammation/Immunology
|
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Asperbisabolane L, a sesquiterpenoid, exerts the anti-inflammatory activity by inhibiting the NF-κB-activated pathway. Asperbisabolane L inhibits the translocation of NF-κB from cytoplasm to the nucleus. Asperbisabolane L also inhibits NO production in LPS-activated BV-2 microglia cells .
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-
-
- HY-N9239
-
|
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Others
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Others
|
|
Turmeronol A is a sesquiterpenoid compound.
Turmeronol A has anti-inflammatory activity. Turmeronol A prevents macrophage
activation and the production of inflammatory mediators by inhibiting the
activation of NFκB. Turmeronol A can be used to prevent chronic inflammatory
diseases .
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-
-
- HY-N8404
-
|
|
Potassium Channel
|
Inflammation/Immunology
|
|
Chlorahololide C, a lindenane sesquiterpenoid dimer, is isolated from Chloranthus holostegius. Chlorahololide C is a potent and selective potassium channel blocker, with an IC50 of 3.6 μM .
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-
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- HY-N10364
-
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Others
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Cancer
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6β,7β-Epoxyasteriscunolide A, a sesquiterpenoid, shows cytotoxicity against the HL-60 and MOLT-3 leukemia cell lines, with IC50s range 4.1-5.4 μM .
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-
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- HY-N10577
-
|
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TGF-beta/Smad
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Cancer
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Chlorfortunone A is a novel sesquiterpenoid dimers, can be isolated from the roots of Chloranthus fortunei. Chlorfortunone A inhibits transforming growth factor (TGF)-β activity .
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-
-
- HY-N0104R
-
|
(-)-Curcumol (Standard)
|
Reference Standards
Apoptosis
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Cancer
|
|
Curcumol (Standard) is the analytical standard of Curcumol. This product is intended for research and analytical applications. Curcumol ((-)-Curcumol), a bioactive sesquiterpenoid, possesses numerous pharmacological activities like anticancer, antimicrobial, antifungal, antiviral, and antiinflammatory. Curcumol is a potent inducer of apoptosis in numerous cancer cells via targeting key signaling pathways as MAPK/ERK, PI3K/Akt and NF-κB which are generally deregulated in several cancers .
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-
-
- HY-N12475
-
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Fungal
Cytochrome P450
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Infection
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Solavetivone is a Sesquiterpenoid phytoalexin and Antifungal agent. Solavetivone is isolated from stress-challenged potato plants. Solavetivone is hydroxylated by sesquiterpenoid phytoalexin hydroxylase (SPH/CYP76A2L). Solavetivone helps solanaceous plants defend against pathogens, damages plant cells after pathogen threat, and inhibits mycelial growth of Rhizoctonia solani. Solavetivone is applicable to studies related to Rhizoctonia solani infection .
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-
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- HY-W587689
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Juvenile hormone III bisepoxide; Juvenile hormone bisepoxide; JHB3
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c-Met/HGFR
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Others
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Juvenile hormone B 3 (Juvenile hormone III bisepoxide)(mixture of diastereomers) is a sesquiterpenoid hormone. Juvenile hormone B 3 can be isolated from corpus allatum (CA) of high dipterans like the fruitfly and Drosophila melanogaster. JHB3 has anti-metamorphic activity and induces Kr-h1 expression by directly interacting with juvenile hormone (JH) receptors (Met and Gce). Juvenile hormone B 3 can be used for insect lethality research .
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-
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- HY-N2885
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-
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- HY-N8312
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Others
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Others
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Bakkenolide IIIa is a natural sesquiterpenoid compound .
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-
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- HY-N9626
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(R)-Cuparene
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Others
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Others
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Cuparene ((R)-Cuparene) is a sesquiterpenoid and can be isolated from Cupressaceae .
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-
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- HY-N3583
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Others
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Others
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Chlorouvedalin is a Sesquiterpenoids product that can be isolated from the herbs of Smallanthus sonchifolius .
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-
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- HY-135444
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NF-κB
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Others
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Heliangin is a Sesquiterpenoids product that can be isolated from the herbs of Helianthus tuberosus L. .
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-
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- HY-N3605
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Others
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Others
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Clovanediol diacetate is a Sesquiterpenoids product that can be isolated from the herbs of Psidium guajava .
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-
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- HY-N3726
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Others
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Others
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Dendocarbin A is a Sesquiterpenoids product that can be isolated from the herbs of Polygonum hydropiper .
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-
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- HY-N11547
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Others
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Others
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Leocarpinolide F is a natural sesquiterpenoid that can be isolated from Siegesbeckia orientalis .
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-
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- HY-N3577
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Others
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Others
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Chlorantholide A is a Sesquiterpenoids product that can be isolated from the herbs of Chloranthus elatior .
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-
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- HY-N3152
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Others
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Others
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O-Geranylconiferyl alcohol is a sesquiterpenoids isolated from the root of Ligularia duciformis .
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-
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- HY-N3046
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Others
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Others
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Piptocarphin A is a Sesquiterpenoids product that can be isolated from the herbs of Vernonia volkameriifolia .
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-
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- HY-N9230
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Others
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Others
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Isocuparenal is a Sesquiterpenoids product that can be isolated from the herbs of Lepidozia reptans .
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-
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- HY-N9302
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Others
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Others
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Chromolaenide is a Sesquiterpenoids product that can be isolated from the herbs of Chromolaena glaberrima. .
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-
- HY-N9116
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Others
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Others
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Unedone is a Sesquiterpenoids product that can be isolated from the herbs of Lysimachia clethroides .
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- HY-N8938
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Others
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Others
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Jasminoid A is a Sesquiterpenoids product that can be isolated from the herbs of Chloranthus japonicus .
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- HY-N3910
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Others
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Others
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Fuegin is a Sesquiterpenoids product that can be isolated from the herb of Polygonum hydropiper .
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- HY-N8657
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Others
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Others
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Pyrocurzerenone is a Sesquiterpenoids product that can be isolated from the herbs of Chloranthus sertusra .
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-
- HY-N3581
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Others
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Others
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Chlorantholide E is a Sesquiterpenoids product that can be isolated from the herbs of Chloranthus elatior .
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-
- HY-N9074
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Others
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Others
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Shizukanolide H is a Sesquiterpenoids product that can be isolated from the herbs of Chloranthus spicatus .
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-
- HY-N8843
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Others
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Others
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Mollisorin A is a Sesquiterpenoids product that can be isolated from the aerial parts of Ophryosporus lorentzii. .
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-
- HY-N3830
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Others
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Others
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Epiguajadial B is a Sesquiterpenoids product that can be isolated from the herbs of Psidium guajava .
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-
- HY-N3982
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Others
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Others
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Guajadial B is a Sesquiterpenoids product that can be isolated from the herbs of Psidium guajava .
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-
- HY-N3582
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Others
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Others
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Enhydrin chlorohydrin is a Sesquiterpenoids product that can be isolated from the herbs of Smallanthus sonchifolius .
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-
- HY-N8778
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Others
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Others
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Intermedin B is a Sesquiterpenoids product that can be isolated from the leaves of Alpinia intermedia. .
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-
- HY-N9221
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Others
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Others
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Bakkenolide III is a Sesquiterpenoids product that can be isolated from the roots of Petasites formosanus. .
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- HY-N3273
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Others
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Others
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Methyl isodrimeninol is a Sesquiterpenoids product that can be isolated from the herbs of Polygonum flaccidum Meissn. .
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- HY-N8795
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Others
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Others
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2-Hydroxyplatyphyllide is a Sesquiterpenoids product that can be isolated from the roots of Ligularia songarica. .
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- HY-N9122
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Others
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Others
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4'-Hydroxypiptocarphin A is a Sesquiterpenoids product that can be isolated from the herbs of Vernonia volkameriifolia .
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-
- HY-N10163
-
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(+)-1β,10β-Epoxydesacetoxymatricarin
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Others
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Others
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1β,10β-Epoxydesacetoxymatricarin is a sesquiterpenoids that can be isolated from Carthamus oxycantha .
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-
- HY-138229
-
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Fungal
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Infection
Cancer
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1β-Acetoxypolygodial is a sesquiterpenoid found in Tasmannia lanceolata. 1β-Acetoxypolygodial is promising for research of cancers and fungal infections .
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-
- HY-176245
-
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Monoamine Oxidase
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Neurological Disease
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Illudinine, a sesquiterpenoid alkaloid, is a monoamine oxidase B (MAO-B) inhibitor with an IC50 of 18.3 μM. Illudinine can be used for research on neurological diseases .
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-
- HY-N15479
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Bacterial
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Infection
Cancer
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Nanangenine F is a drimane sesquiterpenoid with weak antibacterial and anticancer activities. Nanangenine F inhibits Bacillus subtilis (ATCC 6633) with an IC50 of 78 µg/mL. Nanangenine F inhibits NS-1, DU-145, MCF-7 and human fibroblast NFF cells with IC50s of 49 µg/mL, 95 µg/mL, 49 µg/mL, and 84 µg/mL, respectively .
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- HY-N17608
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Others
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Others
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10 (14)-Guaien-11-ol is a guaiane-type sesquiterpenoid that exists in the roots of Jatropha curcas. 10 (14)-Guaien-11-ol shows no significant growth inhibitory activity against human gastric cancer cells .
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- HY-N3537
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Others
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Others
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Canusesnol A is a Sesquiterpenoids product that can be isolated from the herbs of Datura arborea .
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-
- HY-N9209
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Others
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Others
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Cinalbicol is a Sesquiterpenoids product that can be isolated from the roots of Cacalia roborowskii. .
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- HY-N3840
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Others
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Others
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Epoxyparvinolide is a Sesquiterpenoids product that can be isolated from the herbs of Pogostemon parviflorus .
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- HY-N7336
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Others
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Others
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Wedelialactone A is a Sesquiterpenoids product that can be isolated from the herbs of Wedelia trilobata .
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- HY-N4040
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Others
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Others
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Homalomenol A is a Sesquiterpenoids product that can be isolated from the roots of Homalomena aromatica. .
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- HY-N3723
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Others
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Others
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Demethylsonchifolin is a Sesquiterpenoids product that can be isolated from the herbs of Smallanthus sonchifolius .
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-
- HY-N1139
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Others
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Others
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Torilolone is a Sesquiterpenoids product that can be isolated from the herbs of Cnidium monnieri. .
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- HY-N3538
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Others
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Others
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Carabrolactone A is a Sesquiterpenoids product that can be isolated from the rhizomes of Carpesium abrotanoides .
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-
- HY-N2856
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Others
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Others
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Alpiniaterpene A is a Sesquiterpenoids product that can be isolated from the rhizomes of Alpinia officinarum. .
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-
- HY-126205
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Others
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Cancer
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Deacetyleupaserrin is a sesquiterpenoid with antileukemic activity that can be isolated from Eupatorium semiserratum .
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-
- HY-N3499
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Others
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Others
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Isocalamendiol is a Sesquiterpenoids product that can be isolated from the roots of Acorus calamus L. .
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-
- HY-133196
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Others
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Others
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Ustusolate A is a Sesquiterpenoids product that can be isolated from From Aspergillus ustus .
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- HY-N1169
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Others
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Others
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Tectoroside is a Sesquiterpenoids product that can be isolated from the herbs of Crepis crocea. .
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- HY-N9053
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Others
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Others
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Wedeliatrilolactone A is a Sesquiterpenoids product that can be isolated from the herbs of Wedelia trilobata .
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-
- HY-N3038
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Others
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Others
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Polygonal is a Sesquiterpenoids product that can be isolated from the roots of Polygonum hydropiper .
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-
- HY-N1194A
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Others
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Others
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Sulfocostunolide A is a Sesquiterpenoids product that can be isolated from the root of Saussurea lappa .
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-
- HY-N1883
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Others
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Others
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Epoxyarteannuinic acid is a Sesquiterpenoids product that can be isolated from the herbs of Artemisia annua L. .
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-
- HY-N3580
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Others
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Others
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Chlorantholide D is a Sesquiterpenoids product that can be isolated from the herbs of Chloranthus spicatus .
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-
- HY-N15313
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-
- HY-133219A
-
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Others
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Others
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Guajadial D is a Sesquiterpenoids product that can be isolated from the leaves of Psidium guajava. .
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-
- HY-N1194
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Others
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Others
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Sulfocostunolide B is a Sesquiterpenoids product that can be isolated from the roots of Saussurea lappa .
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- HY-N3539
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Others
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Others
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Carabrolactone B is a Sesquiterpenoids product that can be isolated from the rhizomes of Carpesium abrotanoides .
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-
- HY-N9287
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Others
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Others
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Breyniaionoside A is a Sesquiterpenoids product that can be isolated from the leaves of Breynia officinalis HEMSL. .
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-
- HY-N1315
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Others
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Others
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Sarcandrolide D is a Sesquiterpenoids product that can be isolated from the herbs of Sarcandra glabra. .
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- HY-N3578
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Others
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Others
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Chlorantholide B is a Sesquiterpenoids product that can be isolated from the herbs of Chloranthus elatior .
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-
- HY-N1095
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Verbenacin
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Others
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Others
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Verbenacine (Verbenacin) is a Sesquiterpenoids product that can be isolated from the aerial parts of Ophryosporus lorentzii. .
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- HY-N7337
-
|
|
Others
|
Others
|
|
Dibritannilactone B is a Sesquiterpenoids product that can be isolated from the aerial parts of Inula britannica. .
|
-
- HY-N1587
-
|
|
Others
|
Others
|
|
15-Dihydroepioxylubimin is a Sesquiterpenoids product that can be isolated from the herbs of Datura metel .
|
-
- HY-N3833
-
|
|
Others
|
Others
|
|
Epipterosin L is a Sesquiterpenoids product that can be isolated from the rhizomes of Cibotium barometz (L.) J.Sm. .
|
-
- HY-N2804
-
|
|
Others
|
Others
|
|
9-Oxoageraphorone is a Sesquiterpenoids product that can be isolated from the herbs of Eupatorium adenophorum .
|
-
- HY-N9486
-
|
|
Others
|
Others
|
|
2-Hydroxyeupatolide is a Sesquiterpenoids product that can be isolated from the herbs of Eupatorium lindleyanum .
|
-
- HY-N3576
-
|
Chloramultilide D
|
Others
|
Others
|
|
Henriol B (Chloramultilide D) is a dimeric sesquiterpenoid that can be isolated from C. spicatus .
|
-
- HY-N3645
-
|
|
Others
|
Others
|
|
Cucumegastigmane I is a Sesquiterpenoids product that can be isolated from the fruits of Trichosanthes kirilowii Maxim .
|
-
- HY-N1174
-
|
Taxagifin
|
Others
|
Others
|
|
Taxagifine (Taxagifin) is a Sesquiterpenoids product that can be isolated from the leaves of Breynia officinalis HEMSL. .
|
-
- HY-N2904
-
|
|
Others
|
Others
|
|
Ascleposide E is a Sesquiterpenoids product that can be isolated from the roots of Aucklandia lappa Decne .
|
-
- HY-N1144
-
|
Normacusine B; 10-Deoxysarpagine; Vellosiminol
|
Others
|
Others
|
|
Tombozine (Normacusine B) is a Sesquiterpenoids product that can be isolated from the leaves of Alpinia intermedia .
|
-
- HY-N9270
-
|
|
Others
|
Others
|
|
3-Epichromolaenide is a Sesquiterpenoids product that can be isolated from the herbs of Chromolaena glaberrima .
|
-
- HY-N8953
-
|
|
Others
|
Others
|
|
Bisacurone C is a Sesquiterpenoids product that can be isolated from the root tubers of Curcuma longa. .
|
-
- HY-N1840
-
|
|
Others
|
Others
|
|
3-Hydroxycatalponol is a Sesquiterpenoids product that can be isolated from the roots of Ekmanianthe longiflora .
|
-
- HY-N2846
-
|
|
Others
|
Others
|
|
α-Epoxydihydroartemisinic acid is a Sesquiterpenoids product that can be isolated from the herbs of Artemisia annua L. .
|
-
- HY-119528
-
|
|
Bacterial
|
Infection
|
|
Mansonone F is a potent anti-MRSA sesquiterpenoid quinone that can be found in Thespesia populnea .
|
-
- HY-N1042
-
|
|
Others
|
Others
|
|
13-O-Acetylcorianin is a Sesquiterpenoids product that can be isolated from the herbs of Coriaria nepalensis .
|
-
- HY-N8403
-
|
|
Others
|
Others
|
|
Vibralactone B is a Sesquiterpenoids product that can be isolated from From the cultures of the Basidiomycete Boreostereum vibrans. .
|
-
- HY-N9268
-
|
|
Others
|
Others
|
|
8β-Tigloyloxyreynosin is a Sesquiterpenoids product that can be isolated from the roots of Dolomiaea souliei .
|
-
- HY-N1007
-
|
|
Others
|
Others
|
|
10-O-Acetylisocalamendiol is a Sesquiterpenoids product that can be isolated from the roots of Acorus calamus L. .
|
-
- HY-E71239
-
-
- HY-N1862
-
|
|
Others
|
Others
|
|
3-O-Methyltirotundin is a Sesquiterpenoids product that can be isolated from the herbs of Tithonia diversifolia .
|
-
- HY-N9214
-
|
|
Others
|
Others
|
|
1-Oxobakkenolide S is a Sesquiterpenoids product that can be isolated from the roots of Petasites formosanus .
|
-
- HY-N9198
-
|
|
Others
|
Others
|
|
13-O-Ethylpiptocarphol is a Sesquiterpenoids product that can be isolated from the herbs of Vernonia volkameriifolia .
|
-
- HY-N2771
-
|
|
Others
|
Others
|
|
8-Epicrepiside E is a Sesquiterpenoids product that can be isolated from the roots of Saussurea costus .
|
-
- HY-N8959
-
|
|
Others
|
Others
|
|
9-O-Ethyldeacetylorientalide is a Sesquiterpenoids product that can be isolated from the herbs of Euphorbia pekinensis .
|
-
- HY-N8958
-
|
|
Others
|
Others
|
|
Deacetylorientalide (compound 19) is a germacrane-type sesquiterpenoid compound that can be found in from Sigesbeckia orientalis .
|
-
- HY-N2781
-
|
|
Others
|
Others
|
|
8-O-Acetyltorilolone is a Sesquiterpenoids product that can be isolated from the herbs of Cnidium monnieri. .
|
-
- HY-N1015
-
|
|
Others
|
Others
|
|
11,13-Dihydroivalin is a Sesquiterpenoids product that can be isolated from the herbs of Blumea balsamifera .
|
-
- HY-N9103
-
|
|
Others
|
Others
|
|
Norpterosin B glucoside is a Sesquiterpenoids product that can be isolated from the aerial parts of Pteris semipinnata. .
|
-
- HY-N1573
-
|
|
Others
|
Others
|
|
Pterosin Z is a Sesquiterpenoids product that can be isolated from the rhizomes of Cibotium barometz (L.) J.Sm. .
|
-
- HY-N8689
-
|
|
Others
|
Others
|
|
4-Epi-curcumenol is a Sesquiterpenoids product that can be isolated from the rhizomes of Curcuma zedoaria .
|
-
- HY-N3589
-
|
3-Deoxyryanodol
|
Others
|
Others
|
|
Cinnzeylanol (3-Deoxyryanodol) is a Sesquiterpenoids product that can be isolated from the herbs of Datura metel .
|
-
- HY-N1617
-
|
|
Others
|
Others
|
|
1beta-Hydroxytorilin is a Sesquiterpenoids product that can be isolated from the fruits of Torilis japonica. .
|
-
- HY-N3338
-
|
(-)-Macrocarpal K; 9'-epi-Macrocarpal H
|
Others
|
Others
|
|
Macrocarpal K ((-)-Macrocarpal K) is a Sesquiterpenoids product that can be isolated from the herbs of Datura metel .
|
-
- HY-N13889
-
|
|
Fungal
|
Infection
|
|
Altiloxin A, a fungal metabolite, is a drimane-type sesquiterpenoid. Altiloxin A shows phytotoxic activity on the lettuce seedlings .
|
-
- HY-N1892
-
|
O-Demethyleucomin
|
Others
|
Others
|
|
4'-Demethyleucomin (O-Demethyleucomin) is a Sesquiterpenoids product that can be isolated from the herbs of Polygonum hydropiper .
|
-
- HY-N12024
-
|
(-)-Linderanine C
|
Others
|
Others
|
|
Linderanine C ((-)-Linderanine C) (compound 6) is a sesquiterpenoid compound that can be isolated from the roots of Wuyao .
|
-
- HY-N2718
-
|
|
Others
|
Others
|
|
6-O-Acetylcoriatin is a Sesquiterpenoids product that can be isolated from the herbs of Coriaria nepalensis Wall. .
|
-
- HY-N3166
-
|
|
Others
|
Others
|
|
Onitisin 2'-O-glucoside is a Sesquiterpenoids product that can be isolated from the herbs of Onychium japonicum .
|
-
- HY-N2667
-
|
|
Others
|
Others
|
|
5β-Hydroxycostic acid is a Sesquiterpenoids product that can be isolated from the roots of Aucklandia lappa Decne .
|
-
- HY-N3644
-
|
|
Others
|
Others
|
|
Cryptomeridiol 11-rhamnoside is a Sesquiterpenoids product that can be isolated from the branches of Eucalyptus globulus Labill. .
|
-
- HY-N9201
-
|
|
Others
|
Others
|
|
8beta-Methoxyatractylenolide I is a Sesquiterpenoids product that can be isolated from the rhizomes of Atractylodes macrocephala. .
|
-
- HY-N3135
-
|
|
Others
|
Others
|
|
Onitin 2'-O-glucoside is a Sesquiterpenoids product that can be isolated from the herbs of Onychium japonicum .
|
-
- HY-N2793
-
|
|
Others
|
Others
|
|
9-Epiblumenol B is a Sesquiterpenoids product that can be isolated from the herbs of Rosa multiflora Thunb. .
|
-
- HY-N2766
-
|
|
Others
|
Others
|
|
8alpha-Hydroxy-alpha-gurjunene is a Sesquiterpenoids product that can be isolated from the herbs of Sarcandra glabra .
|
-
- HY-N1001
-
|
|
Others
|
Others
|
|
1,9-Caryolanediol 9-acetate is a Sesquiterpenoids product that can be isolated from the herbs of Sindora sumatrana. .
|
-
- HY-E71333
-
-
- HY-N17654
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Neroplomacrol is a sesquiterpenoid and heterocyclic farnesol derivative that occurs in Dalbergia tonkinensis. Neroplomacrol serves as a chemotaxonomic and biochemical marker for Fabaceae .
|
-
- HY-N9260
-
|
|
Others
|
Inflammation/Immunology
|
|
4E-Deacetylchromolaenide 4'-O-acetate (Compound 11) is a sesquiterpenoid that can be isolated fromEupatorium chinense L. .
|
-
- HY-N3829
-
|
|
Others
|
Others
|
|
epi-Eudesmol is a Sesquiterpenoids product that can be isolated from the leaves of Laggera alata var. montana C. D. Adams. .
|
-
- HY-N3161
-
|
20R-Ocotillone
|
Others
|
Others
|
|
Ocotillone Ⅰ (20R-Ocotillone) is a Sesquiterpenoids product that can be isolated from the herbs of Rosa multiflora Thunb. .
|
-
- HY-N1627
-
|
|
Others
|
Others
|
|
2-Prenyl-1-naphthol is a Sesquiterpenoids product that can be isolated from the herbs of Catalpa ovata .
|
-
- HY-N7353
-
|
|
Others
|
Others
|
|
Stachartin C is a Sesquiterpenoids product that can be isolated from the cultures of the tin mine tailings-associated fungus Stachybotrys chartarum. .
|
-
- HY-N2783
-
|
|
Others
|
Others
|
|
8'-Oxo-6-hydroxydihydrophaseic acid is a Sesquiterpenoids product that can be isolated from the roots of Illicium dunnianum. .
|
-
- HY-N3834
-
|
|
Others
|
Others
|
|
Epipterosin L 2'-O-glucoside is a Sesquiterpenoids product that can be isolated from the rhizomes of Cibotium barometz (L.) J.Sm. .
|
-
- HY-N1615
-
|
|
Others
|
Others
|
|
1beta-Hydroxy-beta-eudesmol is a Sesquiterpenoids product that can be isolated from the herbs of Cymbopogon proximus STAPF. .
|
-
- HY-N9114
-
|
1,5,6-Trihydroxyxanthone
|
Others
|
Others
|
|
Mesuaxanthone B (1,5,6-Trihydroxyxanthone) is a Sesquiterpenoids product that can be isolated from the fruits of Torilis japonica. .
|
-
- HY-N15372
-
|
(-)-Heritonin
|
Others
|
Others
|
|
Heritonin ((-)-Heritonin) is a piscicide that can be isolated from the roots of the mangrove plant Heritiera littoralis and belongs to the sesquiterpenoid class of compounds .
|
-
- HY-N1572
-
|
|
Others
|
Others
|
|
Pterosin D 3-O-glucoside is a Sesquiterpenoids product that can be isolated from the rhizomes of Cibotium barometz (L.) J.Sm. .
|
-
- HY-N16737
-
|
|
Others
|
Others
|
|
Trijugin A is a gemmane-type sesquiterpenoid compound that can be isolated from the whole plant of Salvia miltiorrhiza with three pairs of leaves .
|
-
- HY-N9169
-
|
|
Others
|
Others
|
|
8β-(4-Hydroxytigloyloxy)ovatifolin is a Sesquiterpenoids product that can be isolated from the herbs of Eupatorium glehni .
|
-
- HY-N6662
-
-
- HY-N12452
-
|
|
Parasite
|
Infection
|
|
Myrrhterpenoid O (Compound 18) is a sesquiterpenoid compound that exhibits good inhibitory activity against Plasmodium falciparum (IC50 = 21 μM) .
|
-
- HY-N16743
-
|
|
Others
|
Others
|
|
Trijugin B is a gemmane-type sesquiterpenoid that can be isolated from the whole plant of Salvia miltiorrhiza with three pairs of leaves .
|
-
- HY-N9079
-
|
|
Others
|
Others
|
|
8alpha-(2-Methylacryloyloxy)hirsutinolide is a Sesquiterpenoids product that can be isolated from the herbs of Vernonia cinerea. .
|
-
- HY-N9094
-
|
|
Others
|
Others
|
|
8α-Acetoxyarglabin is a Sesquiterpenoids product that can be isolated from the aerial parts of Artemisia Myriantha Wall.Ex Bess. .
|
-
- HY-N9180
-
|
|
Others
|
Others
|
|
8α-Methacryloyloxy-13-ethoxyvernojalcanolide is a Sesquiterpenoids product that can be isolated from the herbs of Vernonia esculenta .
|
-
- HY-N16744
-
|
|
Others
|
Others
|
|
Trijugin C is a gemmane-type sesquiterpenoid that can be isolated from the whole plant of Salvia miltiorrhiza with three pairs of leaves .
|
-
- HY-N9145
-
|
|
Others
|
Others
|
|
1beta,10beta-Epoxydehydroleucodin is a Sesquiterpenoids product that can be isolated from the roots of Scorzonera latifolia .
|
-
- HY-N3590
-
|
|
Others
|
Others
|
|
cis-3,4-Dihydroxy-β-ionone is a Sesquiterpenoids product that can be isolated from the herbs of Gynura nepalensis. .
|
-
- HY-N8117
-
-
- HY-N0999
-
|
|
Others
|
Others
|
|
1,7-Diepi-8,15-cedranediol is a Sesquiterpenoids product that can be isolated from the leaves of Platycladus orientalis .
|
-
- HY-E71220
-
-
- HY-N1869
-
|
|
Others
|
Others
|
|
4(15),11-Oppositadien-1-ol is a Sesquiterpenoids product that can be isolated from the roots of Homalomena aromatica. .
|
-
- HY-N9162
-
|
|
Others
|
Others
|
|
2α-Hydroxyeupatolide 8-O-angelate is a Sesquiterpenoids product that can be isolated from the herbs of Eupatorium chinense var. tozanense. .
|
-
- HY-N3304
-
|
|
Others
|
Others
|
|
7-Megastigmene-3,5,6,9-tetraol is a Sesquiterpenoids product that can be isolated from the herbs of Pandanus amaryllifolius .
|
-
- HY-N8951
-
|
|
Others
|
Others
|
|
3,4-Dihydroxybisabola-1,10-diene is a Sesquiterpenoids product that can be isolated from the rhizomes of Curcuma xanthorrhiza Roxb .
|
-
- HY-N8940
-
|
|
Others
|
Others
|
|
1-O-Acetyl-6-O-isobutyrylbritannilactone is a Sesquiterpenoids product that can be isolated from the flower heads of Inula britannica. .
|
-
- HY-N2691
-
|
|
Others
|
Others
|
|
6,8-Cyclo-1,4-eudesmanediol is a Sesquiterpenoids product that can be isolated from the branches of Eucalyptus robusta Smith .
|
-
- HY-N3783
-
|
|
Others
|
Others
|
|
Drim-7-ene-11,12-diol acetonide is a Sesquiterpenoids product that can be isolated from the herbs of Polygonum hydropiper .
|
-
- HY-N1831
-
|
|
Others
|
Others
|
|
3-Eudesmene-1beta,11-diol is a Sesquiterpenoids product that can be isolated from the herbs of Physalis alkekengi .
|
-
- HY-N1556
-
|
|
Estrogen Receptor/ERR
|
Metabolic Disease
Cancer
|
|
Psidial A is an epimer of sesquiterpenoid-diphenylmethane meroterpenoid. Psidial A may act as a selective estrogen receptors modulator. Psidial A also has potential for anticancer research .
|
-
- HY-N1806
-
|
|
Others
|
Others
|
|
3-Acetoxy-4-cadinen-8-one is a Sesquiterpenoids product that can be isolated from the herbs of Eupatorium adenophorum. .
|
-
- HY-N2767
-
|
|
Others
|
Others
|
|
Naphtho[1,2-b]furan, 2-propenoic acid deriv. is a Sesquiterpenoids product that can be isolated from the herbs of Elephantopus scaber .
|
-
![Naphtho[1,2-b]furan, 2-propenoic acid deriv.](//file.medchemexpress.com/product_pic/hy-n2767.gif)
- HY-N9306
-
|
|
Others
|
Others
|
|
11-Hydroxydrim-7-en-6-one is a Sesquiterpenoids product that can be isolated from the leaves and the bark of Drimys winteri. .
|
-
- HY-N3804
-
|
|
Others
|
Others
|
|
enantio-7(11)-Eudesmen-4-ol is a Sesquiterpenoids product that can be isolated from the herbs of Laggera pterodonta (DC.) Benth. .
|
-
- HY-N2803
-
|
|
Others
|
Others
|
|
9-Oxo-2,7-bisaboladien-15-oic acid is a Sesquiterpenoids product that can be isolated from the barks of Pseudolarix kaempferi .
|
-
- HY-N8756
-
|
|
Others
|
Others
|
|
3-Hydroxybisabola-1,10-dien-9-one is a Sesquiterpenoids product that can be isolated from the leaves of Alpinia intermedia .
|
-
- HY-N12335
-
|
|
Others
|
Others
|
|
Desacetylxanthanol (Compound 4) is a sesquiterpenoid derived from Xanthium strumarium. Desacetylxanthanol has anti-tumor necrosis factor-associated apoptosis-inducing ligand (TRAIL) activity .
|
-
- HY-N12136
-
|
|
Others
|
Others
|
|
1α-Hydroxy-3-deoxypseudoanisatin (Iso-γ-fagarine) is a sesquiterpenoid obtained from star anise (Illicium merrillianum) isolated from the peel .
|
-
- HY-N11989
-
|
|
Others
|
Cancer
|
|
Nanangenine B is a sesquiterpenoid, which can be isolated from Aspergillus nanangensis. Nanangenine B exhibits cytotixicity in cancer cell NS-1 with an IC50 of 38 μg/mL .
|
-
- HY-N1805
-
|
|
Others
|
Others
|
|
3-Acetoxy-4,7(11)-cadinadien-8-one is a Sesquiterpenoids product that can be isolated from the herbs of Eupatorium adenophorum .
|
-
- HY-N8776
-
|
|
Others
|
Others
|
|
11-Hydroxybisabola-1,3,5-trien-9-one is a Sesquiterpenoids product that can be isolated from the leaves of Alpinia intermedia .
|
-
- HY-N12452A
-
|
|
Drug Isomer
|
Infection
|
|
Myrrhterpenoid O enantiomer is a enantiomer of Myrrhterpenoid O (HY-N12452). Myrrhterpenoid O is a sesquiterpenoid compound that exhibits good inhibitory activity against Plasmodium falciparum (IC50 = 21 μM) .
|
-
- HY-N1759
-
|
|
Others
|
Others
|
|
3,11,12-Trihydroxyspirovetiv-1(10)-en-2-one is a Sesquiterpenoids product that can be isolated from the herbs of Datura metel .
|
-
- HY-N9137
-
|
|
Others
|
Others
|
|
2α-Hydroxy-8β-(2-methylbutyryloxy)costunolide is a Sesquiterpenoids product that can be isolated from the aerial parts of Artemisia myriantha .
|
-
- HY-N2694
-
|
|
Others
|
Others
|
|
6,9,10-Trihydroxy-7-megastigmen-3-one is a Sesquiterpenoids product that can be isolated from the roots of Trigonostemon chinensis Merr. .
|
-
- HY-E71281
-
|
|
Biochemical Assay Reagents
|
Others
|
|
β-Chamigrene synthase (EC 4.2.3.78) from the plant Arabidopsis thaliana produces (+)-α-barbatene, (+)-thujopsene and (+)-β-Chamigrene plus traces of other sesquiterpenoids.
|
-
- HY-N17500
-
|
|
Others
|
Others
|
|
Pterosin O is a Pterosin-type sesquiterpenoid. Pterosin O can be isolated from M. strigosa and Pteridium aquilinum (L.) Kuhn. Pterosin O may be regarded as chemotaxonomic markers for M. strigosa .
|
-
- HY-N9282
-
|
|
Others
|
Others
|
|
8alpha-(2-Methylacryloyloxy)-1-O-methylhirsutinolide 13-O-acetate is a Sesquiterpenoids product that can be isolated from the herbs of Vernonia cinerea. .
|
-
- HY-N8946
-
|
|
Others
|
Others
|
|
1-O-Acetyl-6alpha-O-(2-methylbutyryl)britannilactone is a Sesquiterpenoids product that can be isolated from the flower heads of Inula britannica. .
|
-
- HY-N8667
-
|
|
Others
|
Others
|
|
7-Epi-5-eudesmene-1beta,11-diol is a Sesquiterpenoids product that can be isolated from the herbs of Physalis alkekengi .
|
-
- HY-N0974
-
|
|
Others
|
Others
|
|
1,10:4,5-Diepoxy-7(11)-germacren-8-one is a Sesquiterpenoids product that can be isolated from the herbs of Isodon adenantha .
|
-
- HY-N1810
-
|
3α,6β-Ditigloyloxytropan-7β-ol
|
Others
|
Others
|
|
Ditigloylteloidine (3α,6β-Ditigloyloxytropan-7β-ol) is a Sesquiterpenoids product that can be isolated from the herbs of Eupatorium chinense var. tozanense. .
|
-
- HY-N1807
-
|
3-Acetoxy-5-methoxystilbene
|
Others
|
Others
|
|
(E)-3-Acetoxy-5-methoxystilbene (3-Acetoxy-5-methoxystilbene) is a Sesquiterpenoids product that can be isolated from the roots of Ligularia songarica. .
|
-
- HY-N1024
-
|
|
Others
|
Others
|
|
11R,12-Dihydroxyspirovetiv-1(10)-en-2-one is a Sesquiterpenoids product that can be isolated from the herbs of Datura metel .
|
-
- HY-N9091
-
|
|
Others
|
Others
|
|
9α,11-Dihydroxydrim-7-en-6-one is a Sesquiterpenoids product that can be isolated from the leaves and the bark of Drimys winteri .
|
-
- HY-N1024A
-
|
|
Others
|
Others
|
|
11S,12-Dihydroxyspirovetiv-1(10)-en-2-one is a Sesquiterpenoids product that can be isolated from the herbs of Datura metel .
|
-
- HY-N19883
-
|
|
Others
|
Others
|
|
Drim-9(11)-en-8α-ol is a pimarane-type sesquiterpenol. Drim-9(11)-en-8α-ol can be generated via saponification of drim-9(11)-en-8α-yl acetate .
|
-
- HY-N18056
-
|
|
Others
|
Others
|
|
(+)-Norpatchoulenol is an oxygenated sesquiterpene. (+)-Norpatchoulenol exists in the essential oil of Pogostemon patchouli .
|
-
- HY-N1897
-
|
|
Others
|
Others
|
|
4-Hydroxy-11,12,13-trinor-5-eudesmen-7-one is a Sesquiterpenoids product that can be isolated from the roots of Euphorbia fischeriana. .
|
-
- HY-W854294
-
|
|
Others
|
Others
|
|
3,4-Seco-3-oxobisabol-10-ene-4,1-olide is a Sesquiterpenoids product that can be isolated from the leaves of Alpinia intermedia .
|
-
- HY-N1896
-
|
|
Others
|
Others
|
|
4-Hydroxy-1,10-secocadin-5-ene-1,10-dione is a Sesquiterpenoids product that can be isolated from the leaves of Casearia sylvestris. .
|
-
- HY-N9278
-
|
|
Others
|
Others
|
|
8beta-(2-Hydroxy-2-methyl-3-oxobutyryloxy)glucozaluzanin C is a Sesquiterpenoids product that can be isolated from the herbs of Crepis crocea. .
|
-
- HY-N9078
-
|
|
Others
|
Others
|
|
9alpha,11,12-Trihydroxydrim-7-en-6-one is a Sesquiterpenoids product that can be isolated from the leaves and the bark of Drimys winteri .
|
-
- HY-N2850
-
|
5α-Stigmasta-7,22-dien-3β-ol, acetate; Spinasteryl acetate
|
Others
|
Others
|
|
α-Spinasterol acetate (5α-Stigmasta-7,22-dien-3β-ol, acetate) is a Sesquiterpenoids product that can be isolated from the roots of Trigonostemon chinensis Merr. .
|
-
- HY-119635
-
|
|
Others
|
Cancer
|
|
Albicanol is a sesquiterpenoid with potent antioxidant and antagonistic activities against heavy metal toxicity. Albicanol shows cytotoxicity. Albicanol suppress Profenofos (HY-B0832) induced genotoxicity in grass carp hepatocytes .
|
-
- HY-N1837
-
|
|
Others
|
Others
|
|
3-Hydroxy-4,15-dinor-1(5)-xanthen-12,8-olide is a Sesquiterpenoids product that can be isolated from the roots of Xanthium sibiricum .
|
-
- HY-N1885
-
|
|
Others
|
Others
|
|
4alpha,8beta-Dihydroxyeudesm-7(11)-en-12,8-olide is a Sesquiterpenoids product that can be isolated from the herbs of Chloranthus elatior .
|
-
- HY-N9040
-
|
|
Others
|
Others
|
|
6β-Angeloyloxy-1β,10β-epoxy-9-oxo-furaneremophilane is a Sesquiterpenoids product that can be isolated from the herbs of Ligularia songarica. .
|
-
- HY-W006454
-
|
1,5,6-Trihydropyridin-2-one
|
Drug Derivative
|
Others
|
|
5,6-Dihydropyridin-2(1H)-one (1,5,6-Trihydropyridin-2-one) is a Sesquiterpenoids product that can be isolated from the leaves of Alpinia intermedia .
|
-
- HY-182490
-
-
- HY-N9175
-
|
|
Others
|
Others
|
|
4α,6α-Dihydroxyeudesm-11(13)-en-12,8β-olide is a Sesquiterpenoids product that can be isolated from the herbs of Chloranthus elatior .
|
-
- HY-N10913
-
-
- HY-N8881
-
|
Jacaranone ethyl ester
|
Others
|
Others
|
|
Ethyl(1-hydroxy-4-oxocyclohexa-2,5-dien-1-yl)acetate (Jacaranone ethyl ester) is a Sesquiterpenoids product that can be isolated from the rhizomes of Cibotium barometz (L.) J.Sm. .
|
-
- HY-N18354
-
|
|
Others
|
Others
|
|
Tripterygiumine H (Compound 8) is an alkaloid found in the dried roots of Tripterygium wilfordii .
|
-
- HY-N18084
-
|
|
Endogenous Metabolite
|
Others
|
|
Neo-rehmannioside is a carotenoid glycoside that can be isolated from the dried roots of Rehmannia glutinosa .
|
-
- HY-N16856
-
-
- HY-N8830
-
|
|
Others
|
Others
|
|
Selina-4(14),7(11)-dien-8-one is a sesquiterpene that can be isolated from Atractylodes Macrocephala Rhizoma .
|
-
- HY-N17022
-
|
|
Others
|
Others
|
|
Methyl pechueloate is a guaiane-type sesquiterpene ester compound, a potential precursor of xerantholide, and is used in the structural analysis and biosynthetic pathway research of sesquiterpenoid compounds. Methyl pechueloate can be naturally extracted from the aerial parts of Pechuel-Loeschea leibnitziae (Kuntze) O. Hoffm .
|
-
- HY-W750970
-
|
|
Beta-secretase
Cholinesterase (ChE)
|
Neurological Disease
|
|
2-Acetoxyacorenone (compound 8) is a sesquiterpenoid, which can be isolated from the rhizome of Acorus tatarinowii. 2-Acetoxyacorenone has potent AChE and β-BACE1 inhibitory activity and can be used in the study of Alzheimer's disease .
|
-
- HY-E71078
-
|
|
Biochemical Assay Reagents
|
Others
|
|
(E)-2-epi-β-Caryophyllene synthase (EC 4.2.3.137) is found in the plant Selaginella moellendorfii. (E)-2-epi-β-Caryophyllene synthase (EC 4.2.3.137) gives two other sesquiterpenoids.
|
-
- HY-N9187
-
|
|
Others
|
Others
|
|
1α,4β,10β-Trihydroxyguaia-2,11(13)-dien-12,6α-olide is a Sesquiterpenoids product that can be isolated from the rhizomes of Alisma orientale .
|
-
- HY-N8117R
-
|
|
Reference Standards
Biochemical Assay Reagents
|
Inflammation/Immunology
|
|
Bisabolol oxide A (Standard) is the analytical standard of Bisabolol oxide A (HY-N8117). This product is intended for research and analytical applications. Bisabolol oxide A is a bisabolane-type sesquiterpenoid found in the flowers of Matricaria chamomilla. Bisabolol oxide A contributes to the antispasmodic effect of chamomile preparations .
|
-
- HY-N6662S
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
(+)-Longifolene- 13C,d2 is the 13C- and deuterium labeled (+)-Longifolene (HY-N6662). (+)-Longifolene is a sesquiterpenoid and a metabolite in rabbits. (+)-Longifolen is converted to primary, secondary or tertiary alcohols in rabbits, among which the primary alcohol is predominant .
|
-
- HY-N2805
-
|
|
Bacterial
|
Infection
|
|
9-Oxonerolidol is a farnesane-type sesquiterpenoid with anti-pathogens activity. 9-Oxonerolidol can be isolated from Chiliadenus lopadusanus. 9-Oxonerolidol acts as a post-infectional inhibitor from plants, and inhibits Gram+ and Gram? bacteria resistant to the antibiotic .
|
-
- HY-N9018
-
|
|
Others
|
Others
|
|
4-(6-Methyl-4-oxohept-5-en-2-yl)cyclohex-2-en-1-one is a Sesquiterpenoids product that can be isolated from the rhizomes of Curcuma longa .
|
-
- HY-125932A
-
|
|
Serotonin Transporter
|
Neurological Disease
|
|
9β-Debilon is a sesquiterpenoid compound found in Nardostachys chinensis and may possess SERT regulatory activity. Structurally, 9β-Debilon is a diastereomer of Debilon (HY-125932). 9β-Debilon holds potential for research into neurological disorders .
|
-
- HY-E71235
-
|
|
Biochemical Assay Reagents
|
Others
|
|
α-Guaiene synthase (EC 4.2.3.87) requires Mg2+. α-Guaiene synthase (EC 4.2.3.87) can produce trace amounts of α-Guaiene, (-)-patchouliol, Δ-guaiene, and at least ten other sesquiterpenoid compounds.
|
-
- HY-N17540
-
|
|
NO Synthase
|
Inflammation/Immunology
|
|
8-Epiasterolide is a sesquiterpenoid compound isolated from the rhizomes of Atractylodes japonica Koidzumi. 8-Epiasterolide inhibits NO production in LPS (HY-D1056)-treated RAW 264.7 cells. 8-Epiasterolide can be used in the study of inflammatory diseases .
|
-
- HY-E71327
-
|
|
Biochemical Assay Reagents
|
Others
|
|
β-Santalene synthase (EC 4.2.3.83) synthesizes a mixture of sesquiterpenoids from (2E,6E)-farnesyl diphosphate. As well as (-)-β-Santalene (+)-α-santalene and (-)-exo-α-bergamotene are formed with traces of (+)-epi-β-Santalene.
|
-
- HY-E71249
-
|
|
Biochemical Assay Reagents
|
Others
|
|
α-Santalene synthase (EC 4.2.3.82) synthesizes a mixture of sesquiterpenoids from (2E,6E)-farnesyl diphosphate. As well as (+)-α-santalene, (-)-β-Santalene and (-)-exo-α-bergamotene are formed with traces of (+)-epi-β-Santalene.
|
-
- HY-114604
-
|
|
Bacterial
|
Others
|
|
Propioxatin B is a tricyclic sesquiterpenoid compound isolated from the root of vetiver grass. It has anti-tuberculosis activity and inhibitory effects on a variety of drug-resistant mutants of Mycobacterium tuberculosis. In computer simulation docking studies, it showed binding affinity with bacterial DNA gyrase and has a certain safety in vivo.
|
-
- HY-N8936
-
|
|
Others
|
Inflammation/Immunology
|
|
Narchinol B (Compound 4) is a sesquiter penoid
compound. Narchinol B has anti-inflammatory effects. Narchinol B works by
inhibiting proinflammatory mediators, including prostaglandin E2 (PGE2),
inducible nitric oxide synthase (iNOS), and cyclooxygenase-2 (COX-2) proteins,
as well as proinflammatory cytokines, such as interleukin-1b, IL-6, and tumor
necrosis factor-α (TNF-α). Narchinol B significantly inhibits LPS-induced
overproduction of NO in BV2 cells (IC50=2.43 μM)
.
|
-
- HY-N12535
-
|
|
Others
|
Cancer
|
|
Tagitinin C is a sesquiterpenoid compound isolated from the Tithonia diversifolia. Tagitinin C has anticancer activity and can inhibit the proliferation of human glioblastoma U373 cells with an IC50 of 6.1 μg/mL. Tagitinin C can induce U373 cell death and be used in glioblastoma research .
|
-
- HY-N2790
-
|
9,13α-Epidioxy-8(14)-abieten-18-oic acid
|
Others
|
Others
|
|
9α,13α-Epidioxyabiet-8(14)-en-18-oic acid (9,13α-Epidioxy-8(14)-abieten-18-oic acid) is a Sesquiterpenoids product that can be isolated from the rhizomes of Carpesium abrotanoides .
|
-
- HY-N9119
-
-
- HY-N8413
-
|
|
Toll-like Receptor (TLR)
Reactive Oxygen Species (ROS)
NF-κB
|
Inflammation/Immunology
|
|
Chlojaponilactone B is a lindenane-type sesquiterpenoid with anti-inflammatory properties. Chlojaponilactone B suppresses inflammatory responses by inhibiting TLR4 and subsequently decreasing reactive oxygen species (ROS) generation, downregulating the NF-κB, thus reducing the expression of the pro-inflammatory cytokines iNOS, NO, COX-2, IL-6 and TNF-α .
|
-
- HY-N8284
-
-
- HY-103524
-
|
(-)-Valerenic Acid
|
GABA Receptor
5-HT Receptor
|
Neurological Disease
|
|
Valerenic acid ((-)-Valerenic Acid), a sesquiterpenoid, is an orally active positive allosteric modulator of GABAA receptors. Valerenic acid is also a partial agonist of the 5-HT5a receptor. Valerenic acid mediates anxiolytic activity via GABAA receptors containing the β3 subunit. Valerenic acid also exhibits potent antioxidant properties .
|
-
- HY-N10750
-
|
|
Others
|
Others
|
|
1α, 2α-Diacetoxy-8β-isobutanoyloxy-9α-benzoyloxy-15-β-(β-furancarbonyloxy)-4β, 6β-dihydroxy-β-dihydroagarofuran (compound 7) is an eudesmane-type sesquiterpenoid that can be founfd in the the root bark of Pseudolarix kaempferi .
|
-
- HY-N18101
-
|
|
Others
|
Endocrinology
|
|
Corymbolone is an eudesmane-type sesquiterpene ketol found in the rhizomes of Cyperus corymbosus. Corymbolone can be used in research on gynecological diseases .
|
-
- HY-N15582
-
|
|
Apoptosis
|
Inflammation/Immunology
Cancer
|
|
Perezone is a sesquiterpenoid benzoquinone found in the roots of Acourtia species. Perezone inhibits the activity of leukemia cell line K-562 and human glioma cell line U-251 (IC50: 6.83 μM). Perezone increases the expression of caspase 3, 8, and 9 genes associated with apoptosis. Perezone has antioxidant and anti-inflammatory activities .
|
-
- HY-N1614
-
|
|
Others
|
Others
|
|
1 α-hydroxytorilin (compound 3) is a sesquiterpenoid. 1 α-hydroxytorilin can be isolated from Torilis japonica. 1α-hydroxytorilin has cytotoxicity against human A549, SK-OV-3, SK-MEL-2, and HCT15 tumor cells with ED50 values of 20.52, 18.24, 17.48, 42.54 μg/mL, respectively .
|
-
- HY-103524R
-
|
(-)-Valerenic Acid (Standard)
|
5-HT Receptor
GABA Receptor
Reference Standards
|
Neurological Disease
|
|
Valerenic acid (Standard) is the analytical standard of Valerenic acid. This product is intended for research and analytical applications. Valerenic acid ((-)-Valerenic Acid), a sesquiterpenoid, is an orally active positive allosteric modulator of GABAA receptors. Valerenic acid is also a partial agonist of the 5-HT5a receptor. Valerenic acid mediates anxiolytic activity via GABAA receptors containing the β3 subunit. Valerenic acid also exhibits potent antioxidant properties .
|
-
- HY-N0202
-
|
Asterolide
|
ERK
Apoptosis
p38 MAPK
Akt
Src
STAT
|
Cardiovascular Disease
Neurological Disease
Inflammation/Immunology
Cancer
|
|
Atractylenolide II (Asterolide) is a sesquiterpenoid compound. Atractylenolide II can induce G1 phase cell cycle arrest and apoptosis in B16 melanoma cells. Atractylenolide II is an orally effective anticancer agent that can exert anti-melanoma effects by inhibiting the STAT3 signaling pathway. In addition, Atractylenolide II has been shown to ameliorate myocardial fibrosis, oxidative stress, and neuroprotective activity .
|
-
- HY-121239
-
|
|
NF-κB
|
Neurological Disease
Inflammation/Immunology
Cancer
|
|
Lemnalol is a potent agent for neuropathic pain. Lemnalol possesses potent anti-inflammatory, analgesic and anti-tumor activities. Lemnalol has the capacity to attenuate hyperalgesia and allodynia by modulation of neuroinflammatory processes in neuropathy. Lemnalol modulates LPS-induced alterations of left atrial (LA) calcium homeostasis and blocks the NF-κB pathways, which may contribute to the attenuation of lipopolysaccharide (LPS)-induced arrhythmogenesis and neuropathic pain. Lemnalolis a ylangene-type sesquiterpenoid compound, isolated from Lemnalia cervicorni .
|
-
- HY-N7872
-
|
|
NO Synthase
|
Inflammation/Immunology
|
|
Ac-wilforsinine N (Compound 11) is a natural product. Ac-wilforsinine N can be isolated from the dried root of Tripterygium wilfordii. Ac-wilforsinine N is inactive against NO production in cells. Ac-wilforsinine N can be used in the research of inflammatory diseases .
|
-
- HY-W006454R
-
|
1,5,6-Trihydropyridin-2-one (Standard)
|
Others
Reference Standards
|
Others
|
|
5,6-Dihydropyridin-2(1H)-one (Standard) is the analytical standard of 5,6-Dihydropyridin-2(1H)-one (HY-W006454). This product is intended for research and analytical applications. 5,6-Dihydropyridin-2(1H)-one (1,5,6-Trihydropyridin-2-one) is a Sesquiterpenoids product that can be isolated from the leaves of Alpinia intermedia .
|
-
- HY-N0202R
-
|
Asterolide (Standard)
|
ERK
Reference Standards
Apoptosis
p38 MAPK
Src
Akt
STAT
|
Cardiovascular Disease
Neurological Disease
Inflammation/Immunology
Cancer
|
|
Atractylenolide II (Standard) is the analytical standard of Atractylenolide II. This product is intended for research and analytical applications. Atractylenolide II (Asterolide) is a sesquiterpenoid compound. Atractylenolide II can induce G1 phase cell cycle arrest and apoptosis in B16 melanoma cells. Atractylenolide II is an orally effective anticancer agent that can exert anti-melanoma effects by inhibiting the STAT3 signaling pathway. In addition, Atractylenolide II has been shown to ameliorate myocardial fibrosis, oxidative stress, and neuroprotective activity .
|
-
- HY-N1870
-
|
|
Bacterial
|
Others
|
|
1β-Hydroxy-4(15),5E,10(14)-germacratriene (compound 17) is a sesquiterpenoids that can be isolated from Chrysanthemum indicum.1β-Hydroxy-4(15),5E,10(14)-germacratriene significantly reduces PEDV nucleocapsid and spike protein synthesis.1β-Hydroxy-4(15),5E,10(14)-germacratriene shows various biological properties, such as antibacterial, antioxidant, and anti-inflammatory .
|
-
- HY-N16692
-
|
|
Bacterial
|
Infection
|
|
Shizukolidol is an antimicrobial agent that can be isolated from polyfollicles of Magnolia vovidessi. Shizukolidol shows antibacterial activity against Chryseobacterium sp. Shizukolidol can be used for the research of bacterial infection .
|
-
- HY-N3980
-
Guaiol
1 Publications Verification
Champacol; Guaiac alcohol
|
Autophagy
RAD51
|
Infection
Cardiovascular Disease
Inflammation/Immunology
Cancer
|
|
Guaiol is a sesquiterpenoid alcohol with oral activity found in various traditional Chinese medicines, exhibiting biological activities such as anti-proliferative, autophagy-promoting, insecticidal, anti-anxiety, anti-inflammatory, diuretic, and blood pressure-lowering effects. Guaiol induces apoptosis in non-small cell lung cancer cells by regulating the stability of RAD51 through autophagy modulation. Guaiol can also act directly on parasites, inhibiting their growth by affecting the kinetoplast, mitochondrial matrix and plasma membrane of the promastigotes. Guaiol kills amastigotes at an IC50 of 0.01 µg/mL. Guaiol can be used in research related to cancer, infections, cardiovascular diseases, and inflammatory conditions [4]
|
-
- HY-N3980R
-
|
Champacol (Standard); Guaiac alcohol (Standard)
|
Reference Standards
Autophagy
RAD51
|
Infection
Cardiovascular Disease
Inflammation/Immunology
Cancer
|
|
Guaiol (Standard) is the analytical standard of Guaiol. This product is intended for research and analytical applications. Guaiol is a sesquiterpenoid alcohol with oral activity found in various traditional Chinese medicines, exhibiting biological activities such as anti-proliferative, autophagy-promoting, insecticidal, anti-anxiety, anti-inflammatory, diuretic, and blood pressure-lowering effects. Guaiol induces apoptosis in non-small cell lung cancer cells by regulating the stability of RAD51 through autophagy modulation. Guaiol can also act directly on parasites, inhibiting their growth by affecting the kinetoplast, mitochondrial matrix and plasma membrane of the promastigotes. Guaiol kills amastigotes at an IC50 of 0.01 µg/mL. Guaiol can be used in research related to cancer, infections, cardiovascular diseases, and inflammatory conditions [4]
|
-
- HY-N7282
-
-
- HY-121388
-
|
(+)-Ledol
|
Fungal
|
Infection
|
|
Ledol ((+)-Ledol) is an antifungal agent isolated from the volatile oil components of Rhododendron tomentosum. Ledol also acts as an expectorant and antitussive, while it can cause adverse reactions such as dizziness, nausea and vomiting .
|
-
- HY-N2423B
-
|
(E/Z)-Allyl-glucosinolate free base; (E/Z)-2-Propenyl-glucosinolate free base
|
NF-κB
p38 MAPK
Apoptosis
|
Cardiovascular Disease
Infection
Inflammation/Immunology
Cancer
|
|
(E/Z)-Sinigrin ((E/Z)-Allyl-glucosinolate; (E/Z)-2-Propenyl-glucosinolate) free base is an orally active aliphatic thioglucoside anti-leukemia compound. Allyl isothiocyanate, produced by the hydrolysis of (E/Z)-sinigrin free base by myrosinase, has an IC50 of 2.71 μM against HL60 leukemia cells. The hydrolysis products of (E/Z)-sinigrin free base can further activate apoptosis pathways, inhibit NF-κB and MAPK signaling pathways, and induce phase II metabolic enzyme activity, thus exhibiting anti-cancer, anti-inflammatory, antibacterial, antioxidant, and wound healing activities. (E/Z)-Sinigrin free base can be used in research on cancer, inflammation-related diseases (such as atherosclerosis), and infectious diseases. (E/Z)-Sinigrin free base can be naturally extracted from the seeds of Brassica nigra, Brassica juncea, and other Brassicaceae plants such as broccoli and Brussels sprouts. Methyl pechueloate is a guaiane-type sesquiterpene ester compound and a potential precursor of xerantholide. It is useful in the structural elucidation and biosynthetic pathway studies of sesquiterpenoids. Methyl pechueloate can be naturally extracted from the aerial parts of Pechuel-Loeschea leibnitziae (Kuntze) O. Hoffm .
|
-
- HY-N0353R
-
|
(+)-Curdione (Standard)
|
Reference Standards
Ferroptosis
Apoptosis
Reactive Oxygen Species (ROS)
Autophagy
Glutathione Peroxidase
Keap1-Nrf2
Heme Oxygenase (HO)
TGF-β Receptor
Indoleamine 2,3-Dioxygenase (IDO)
|
Others
|
|
Curdione (Standard) is the analytical standard of Curdione. This product is intended for research and analytical applications. Curdione ((+)-Curdione) is an orally active sesquiterpenoid. Curdione inhibits platelet aggregation. Curdione induces ferroptosis in colorectal cancer via m6A methylation mediated by METTL14 and YTHDF2. Curdione inhibits ferroptosis in Isoproterenol (HY-B0468)-induced myocardial infarction by regulating the Keap1/Trx1/GPX4 signaling pathway, suppressing oxidative stress (ROS) and apoptosis. Curdione ameliorates Doxorubicin (HY-15142)-induced cardiotoxicity by inhibiting oxidative stress (ROS) and activating the Nrf2/HO-1 pathway. Curdione ameliorates sepsis-induced lung injury by inhibiting platelet-mediated neutrophil extracellular trap formation. Curdione ameliorates Bleomycin (HY-17565A)-induced pulmonary fibrosis by inhibiting TGF-β-induced fibroblast-to-myofibroblast differentiation. Curdione exhibits neuroprotective effects against focal cerebral ischemia-reperfusion injury in rats. Curdione exerts antiproliferative effects against human uterine leiomyosarcoma by targeting IDO1. Curdione protects vascular endothelial cells and atherosclerosis by regulating DNMT1-mediated ERBB4 promoter methylation. Curdione inhibits inducible prostaglandin E2 production (IC50 = 1.1 μM) and cyclooxygenase 2 expression .
|
-
- HY-N0353
-
|
(+)-Curdione
|
Ferroptosis
Apoptosis
Reactive Oxygen Species (ROS)
Autophagy
Glutathione Peroxidase
Keap1-Nrf2
Heme Oxygenase (HO)
TGF-β Receptor
Indoleamine 2,3-Dioxygenase (IDO)
|
Cardiovascular Disease
Neurological Disease
Cancer
|
|
Curdione ((+)-Curdione) is an orally active sesquiterpenoid. Curdione inhibits platelet aggregation. Curdione induces ferroptosis in colorectal cancer via m6A methylation mediated by METTL14 and YTHDF2. Curdione inhibits ferroptosis in Isoproterenol (HY-B0468)-induced myocardial infarction by regulating the Keap1/Trx1/GPX4 signaling pathway, suppressing oxidative stress (ROS) and apoptosis. Curdione ameliorates Doxorubicin (HY-15142)-induced cardiotoxicity by inhibiting oxidative stress (ROS) and activating the Nrf2/HO-1 pathway. Curdione ameliorates sepsis-induced lung injury by inhibiting platelet-mediated neutrophil extracellular trap formation. Curdione ameliorates Bleomycin (HY-17565A)-induced pulmonary fibrosis by inhibiting TGF-β-induced fibroblast-to-myofibroblast differentiation. Curdione exhibits neuroprotective effects against focal cerebral ischemia-reperfusion injury in rats. Curdione exerts antiproliferative effects against human uterine leiomyosarcoma by targeting IDO1. Curdione protects vascular endothelial cells and atherosclerosis by regulating DNMT1-mediated ERBB4 promoter methylation. Curdione inhibits inducible prostaglandin E2 production (IC50 = 1.1 μM) and cyclooxygenase 2 expression .
|
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| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
- HY-N8657
-
-
- HY-N3581
-
-
- HY-N9074
-
-
- HY-N8843
-
-
- HY-N3830
-
-
- HY-N3982
-
-
- HY-N3582
-
-
- HY-N8778
-
-
- HY-N9221
-
-
- HY-N3273
-
-
- HY-N8795
-
-
- HY-N9122
-
-
- HY-N9486
-
-
- HY-N3576
-
-
- HY-N3645
-
-
- HY-N10163
-
-
- HY-138229
-
-
- HY-N15479
-
|
|
Microorganisms
Terpenoids
Sesquiterpenes
Source Classification
|
Bacterial
|
|
Nanangenine F is a drimane sesquiterpenoid with weak antibacterial and anticancer activities. Nanangenine F inhibits Bacillus subtilis (ATCC 6633) with an IC50 of 78 µg/mL. Nanangenine F inhibits NS-1, DU-145, MCF-7 and human fibroblast NFF cells with IC50s of 49 µg/mL, 95 µg/mL, 49 µg/mL, and 84 µg/mL, respectively .
|
-
- HY-N17608
-
-
- HY-N3537
-
-
- HY-N9209
-
-
- HY-N3840
-
-
- HY-N7336
-
-
- HY-N4040
-
-
- HY-N3723
-
-
- HY-N1139
-
-
- HY-N3538
-
-
- HY-N2856
-
-
- HY-126205
-
-
- HY-N3499
-
-
- HY-133196
-
-
- HY-N1169
-
-
- HY-N9053
-
-
- HY-N3038
-
-
- HY-N1194A
-
-
- HY-N1883
-
-
- HY-N3580
-
-
- HY-N15313
-
-
- HY-133219A
-
-
- HY-N1194
-
-
- HY-N3539
-
-
- HY-N9287
-
-
- HY-N1315
-
-
- HY-N3578
-
-
- HY-N1095
-
-
- HY-N7337
-
-
- HY-N1587
-
-
- HY-N3833
-
-
- HY-N2804
-
-
- HY-N1174
-
-
- HY-N2904
-
-
- HY-N1144
-
-
- HY-N9270
-
-
- HY-N8953
-
-
- HY-N1840
-
-
- HY-N2846
-
-
- HY-119528
-
-
- HY-N1042
-
-
- HY-N8403
-
-
- HY-N9268
-
-
- HY-N1007
-
-
- HY-N1862
-
-
- HY-N9214
-
-
- HY-N9198
-
-
- HY-N2771
-
-
- HY-N8959
-
-
- HY-N8958
-
-
- HY-N2781
-
-
- HY-N1015
-
-
- HY-N9103
-
-
- HY-N1573
-
-
- HY-N8689
-
-
- HY-N3589
-
-
- HY-N1617
-
-
- HY-N3338
-
-
- HY-N13889
-
-
- HY-N1892
-
-
- HY-N12024
-
-
- HY-N2718
-
-
- HY-N3166
-
-
- HY-N2667
-
-
- HY-N3644
-
-
- HY-N9201
-
-
- HY-N3135
-
-
- HY-N2793
-
-
- HY-N2766
-
-
- HY-N1001
-
-
- HY-N17654
-
-
- HY-N9260
-
-
- HY-N3829
-
-
- HY-N3161
-
-
- HY-N1627
-
-
- HY-N7353
-
-
- HY-N2783
-
-
- HY-N3834
-
-
- HY-N1615
-
-
- HY-N9114
-
-
- HY-N15372
-
-
- HY-N1572
-
-
- HY-N16737
-
-
- HY-N9169
-
-
- HY-N6662
-
-
- HY-N12452
-
-
- HY-N16743
-
-
- HY-N9079
-
-
- HY-N9094
-
-
- HY-N9180
-
-
- HY-N16744
-
-
- HY-N9145
-
-
- HY-N3590
-
-
- HY-N8117
-
-
- HY-N0999
-
-
- HY-N1869
-
-
- HY-N9162
-
-
- HY-N3304
-
-
- HY-N8951
-
-
- HY-N8940
-
-
- HY-N2691
-
-
- HY-N3783
-
-
- HY-N1831
-
-
- HY-N1556
-
-
- HY-N1806
-
-
- HY-N2767
-
-
- HY-N9306
-
-
- HY-N3804
-
-
- HY-N2803
-
-
- HY-N8756
-
-
- HY-N12335
-
-
- HY-N12136
-
-
- HY-N11989
-
-
- HY-N1805
-
-
- HY-N8776
-
-
- HY-N12452A
-
-
- HY-N1759
-
-
- HY-N9137
-
-
- HY-N2694
-
-
- HY-N17500
-
-
- HY-N9282
-
-
- HY-N8946
-
-
- HY-N8667
-
-
- HY-N0974
-
-
- HY-N1810
-
-
- HY-N1807
-
-
- HY-N1024
-
-
- HY-N9091
-
-
- HY-N1024A
-
-
- HY-N19883
-
-
- HY-N18056
-
-
- HY-N1897
-
-
- HY-W854294
-
-
- HY-N1896
-
-
- HY-N9278
-
-
- HY-N9078
-
-
- HY-N2850
-
-
- HY-119635
-
-
- HY-N1837
-
-
- HY-N1885
-
-
- HY-N9040
-
-
- HY-W006454
-
-
- HY-182490
-
-
- HY-N9175
-
-
- HY-N10913
-
-
- HY-N8881
-
-
- HY-N18354
-
-
- HY-N18084
-
-
- HY-N16856
-
-
- HY-N8830
-
-
- HY-N17022
-
-
- HY-W750970
-
-
- HY-N9187
-
-
- HY-N8117R
-
-
- HY-N2805
-
-
- HY-N9018
-
-
- HY-125932A
-
-
- HY-N17540
-
-
- HY-114604
-
|
|
Natural Products
Microorganisms
Source Classification
|
Bacterial
|
|
Propioxatin B is a tricyclic sesquiterpenoid compound isolated from the root of vetiver grass. It has anti-tuberculosis activity and inhibitory effects on a variety of drug-resistant mutants of Mycobacterium tuberculosis. In computer simulation docking studies, it showed binding affinity with bacterial DNA gyrase and has a certain safety in vivo.
|
-
- HY-N8936
-
|
|
Terpenoids
Sesquiterpenes
Nardostachys jatamansi (D. Don) DC.
Plants
Valerianaceae
Source Classification
|
Others
|
|
Narchinol B (Compound 4) is a sesquiter penoid
compound. Narchinol B has anti-inflammatory effects. Narchinol B works by
inhibiting proinflammatory mediators, including prostaglandin E2 (PGE2),
inducible nitric oxide synthase (iNOS), and cyclooxygenase-2 (COX-2) proteins,
as well as proinflammatory cytokines, such as interleukin-1b, IL-6, and tumor
necrosis factor-α (TNF-α). Narchinol B significantly inhibits LPS-induced
overproduction of NO in BV2 cells (IC50=2.43 μM)
.
|
-
- HY-N12535
-
-
- HY-N2790
-
-
- HY-N9119
-
-
- HY-N8413
-
-
- HY-N8284
-
-
- HY-N10750
-
-
- HY-N18101
-
-
- HY-N15582
-
-
- HY-N1614
-
-
- HY-N0202
-
-
- HY-121239
-
|
|
Structural Classification
Natural Products
Animals
Source Classification
|
NF-κB
|
|
Lemnalol is a potent agent for neuropathic pain. Lemnalol possesses potent anti-inflammatory, analgesic and anti-tumor activities. Lemnalol has the capacity to attenuate hyperalgesia and allodynia by modulation of neuroinflammatory processes in neuropathy. Lemnalol modulates LPS-induced alterations of left atrial (LA) calcium homeostasis and blocks the NF-κB pathways, which may contribute to the attenuation of lipopolysaccharide (LPS)-induced arrhythmogenesis and neuropathic pain. Lemnalolis a ylangene-type sesquiterpenoid compound, isolated from Lemnalia cervicorni .
|
-
- HY-N7872
-
-
- HY-W006454R
-
-
- HY-N0202R
-
-
- HY-N1870
-
|
|
Terpenoids
Sesquiterpenes
Erythrina abyssinica Lam.
Plants
Compositae
Source Classification
|
Bacterial
|
|
1β-Hydroxy-4(15),5E,10(14)-germacratriene (compound 17) is a sesquiterpenoids that can be isolated from Chrysanthemum indicum.1β-Hydroxy-4(15),5E,10(14)-germacratriene significantly reduces PEDV nucleocapsid and spike protein synthesis.1β-Hydroxy-4(15),5E,10(14)-germacratriene shows various biological properties, such as antibacterial, antioxidant, and anti-inflammatory .
|
-
- HY-N16692
-
-
- HY-N3980
-
Guaiol
1 Publications Verification
Champacol; Guaiac alcohol
|
Infection
Structural Classification
Classification of Application Fields
Terpenoids
Sesquiterpenes
Distemonanthus benthamianus Baill.
Plants
Compositae
Disease Research Fields
Source Classification
|
Autophagy
RAD51
|
|
Guaiol is a sesquiterpenoid alcohol with oral activity found in various traditional Chinese medicines, exhibiting biological activities such as anti-proliferative, autophagy-promoting, insecticidal, anti-anxiety, anti-inflammatory, diuretic, and blood pressure-lowering effects. Guaiol induces apoptosis in non-small cell lung cancer cells by regulating the stability of RAD51 through autophagy modulation. Guaiol can also act directly on parasites, inhibiting their growth by affecting the kinetoplast, mitochondrial matrix and plasma membrane of the promastigotes. Guaiol kills amastigotes at an IC50 of 0.01 µg/mL. Guaiol can be used in research related to cancer, infections, cardiovascular diseases, and inflammatory conditions [4]
|
-
- HY-N3980R
-
|
Champacol (Standard); Guaiac alcohol (Standard)
|
Structural Classification
Natural Products
Distemonanthus benthamianus Baill.
Plants
Compositae
Source Classification
|
Reference Standards
Autophagy
RAD51
|
|
Guaiol (Standard) is the analytical standard of Guaiol. This product is intended for research and analytical applications. Guaiol is a sesquiterpenoid alcohol with oral activity found in various traditional Chinese medicines, exhibiting biological activities such as anti-proliferative, autophagy-promoting, insecticidal, anti-anxiety, anti-inflammatory, diuretic, and blood pressure-lowering effects. Guaiol induces apoptosis in non-small cell lung cancer cells by regulating the stability of RAD51 through autophagy modulation. Guaiol can also act directly on parasites, inhibiting their growth by affecting the kinetoplast, mitochondrial matrix and plasma membrane of the promastigotes. Guaiol kills amastigotes at an IC50 of 0.01 µg/mL. Guaiol can be used in research related to cancer, infections, cardiovascular diseases, and inflammatory conditions [4]
|
-
- HY-N7282
-
-
- HY-121388
-
-
- HY-N2423B
-
|
(E/Z)-Allyl-glucosinolate free base; (E/Z)-2-Propenyl-glucosinolate free base
|
Structural Classification
Glucosinolates
Plants
Brassicaceae
Source Classification
Mutarda nigra (L.) Bernh.
|
NF-κB
p38 MAPK
Apoptosis
|
|
(E/Z)-Sinigrin ((E/Z)-Allyl-glucosinolate; (E/Z)-2-Propenyl-glucosinolate) free base is an orally active aliphatic thioglucoside anti-leukemia compound. Allyl isothiocyanate, produced by the hydrolysis of (E/Z)-sinigrin free base by myrosinase, has an IC50 of 2.71 μM against HL60 leukemia cells. The hydrolysis products of (E/Z)-sinigrin free base can further activate apoptosis pathways, inhibit NF-κB and MAPK signaling pathways, and induce phase II metabolic enzyme activity, thus exhibiting anti-cancer, anti-inflammatory, antibacterial, antioxidant, and wound healing activities. (E/Z)-Sinigrin free base can be used in research on cancer, inflammation-related diseases (such as atherosclerosis), and infectious diseases. (E/Z)-Sinigrin free base can be naturally extracted from the seeds of Brassica nigra, Brassica juncea, and other Brassicaceae plants such as broccoli and Brussels sprouts. Methyl pechueloate is a guaiane-type sesquiterpene ester compound and a potential precursor of xerantholide. It is useful in the structural elucidation and biosynthetic pathway studies of sesquiterpenoids. Methyl pechueloate can be naturally extracted from the aerial parts of Pechuel-Loeschea leibnitziae (Kuntze) O. Hoffm .
|
-
- HY-N0353R
-
|
(+)-Curdione (Standard)
|
Structural Classification
Terpenoids
Sesquiterpenes
Curcuma phaeocaulis Valeton
Plants
Source Classification
Zingiberaceae
|
Reference Standards
Ferroptosis
Apoptosis
Reactive Oxygen Species (ROS)
Autophagy
Glutathione Peroxidase
Keap1-Nrf2
Heme Oxygenase (HO)
TGF-β Receptor
Indoleamine 2,3-Dioxygenase (IDO)
|
|
Curdione (Standard) is the analytical standard of Curdione. This product is intended for research and analytical applications. Curdione ((+)-Curdione) is an orally active sesquiterpenoid. Curdione inhibits platelet aggregation. Curdione induces ferroptosis in colorectal cancer via m6A methylation mediated by METTL14 and YTHDF2. Curdione inhibits ferroptosis in Isoproterenol (HY-B0468)-induced myocardial infarction by regulating the Keap1/Trx1/GPX4 signaling pathway, suppressing oxidative stress (ROS) and apoptosis. Curdione ameliorates Doxorubicin (HY-15142)-induced cardiotoxicity by inhibiting oxidative stress (ROS) and activating the Nrf2/HO-1 pathway. Curdione ameliorates sepsis-induced lung injury by inhibiting platelet-mediated neutrophil extracellular trap formation. Curdione ameliorates Bleomycin (HY-17565A)-induced pulmonary fibrosis by inhibiting TGF-β-induced fibroblast-to-myofibroblast differentiation. Curdione exhibits neuroprotective effects against focal cerebral ischemia-reperfusion injury in rats. Curdione exerts antiproliferative effects against human uterine leiomyosarcoma by targeting IDO1. Curdione protects vascular endothelial cells and atherosclerosis by regulating DNMT1-mediated ERBB4 promoter methylation. Curdione inhibits inducible prostaglandin E2 production (IC50 = 1.1 μM) and cyclooxygenase 2 expression .
|
-
- HY-N0353
-
-
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-N6662S
-
|
|
|
(+)-Longifolene- 13C,d2 is the 13C- and deuterium labeled (+)-Longifolene (HY-N6662). (+)-Longifolene is a sesquiterpenoid and a metabolite in rabbits. (+)-Longifolen is converted to primary, secondary or tertiary alcohols in rabbits, among which the primary alcohol is predominant .
|
-
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![Naphtho[1,2-b]furan, 2-propenoic acid deriv.](http://file.medchemexpress.com/product_pic/hy-n2767.gif)
