9 Results for "

stomach carcinoma

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "stomach carcinoma" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-12204
CAS No.: 4382-63-2
Purity:  99.80%
Target:  

Autophagy

PFK-015, a derivative of 3PO, is a specific PFKFB3 inhibitor. PFK-015 inhibits recombinant PFKFB3 with an IC50 value of 110 nM and inhibits PFKFB3 activity in cancer cells with an IC50 value of 20 nM. PFK-015 can be used for the research of multiple cancers such as lung cancer, stomach cancer, colon cancer and esophageal squamous cell carcinoma (ESCC) .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W854385A
Synonyms: SLeA sodium
Research Areas:  

Cancer

Sialyl Lewis A (SLeA) sodium is a tumor-associated carbohydrate antigen, also known as carbohydrate antigen 19-9 (CA19-9), that binds to E-selectin (ELAM-1) and selectins to mediate cell-endothelium adhesion. Sialyl Lewis A sodium promotes cancer cell-vascular endothelium adhesion, and its surface presence correlates with increased tumorigenicity and invasiveness in cancer cells. Sialyl Lewis A sodium shows elevated expression in human adenocarcinomas of the colon, pancreas, and stomach, with expression levels linked to tumor progression and poor prognosis in colorectal and gastric carcinomas. Sialyl Lewis A sodium can be used for the research of cancers, such as colon, pancreas, stomach, and squamous lung cancer .
loading...
    loading...
Cat. No.: HY-104004
CAS No.: 120173-57-1
Purity:  98.11%
Synonyms: Fmoc-Ser-(GalNAc(Ac)3-alpha-D)-OH; Fmoc-Ser[GalNAc(Ac)3-α-D]-OH; Fmoc-Ser(Ac3AcNH-α-Gal)-OH
Research Areas:  

Cancer

Fmoc-Ser (O-α-D-GalNAc (OAc) 3)-OH (Fmoc-Ser-(GalNAc(Ac)3-alpha-D)-OH) is a protected glycosylated amino acid and Tn antigen. Fmoc-Ser (O-α-D-GalNAc (OAc) 3)-OH serves as a building block in the solid-phase synthesis of Tn-based cancer vaccine constructs. Fmoc-Ser (O-α-D-GalNAc (OAc) 3)-OH supports solid-phase peptide synthesis .
loading...
    loading...
Cat. No.: HY-W854385
CAS No.: 92448-22-1
Synonyms: SLeA
Research Areas:  

Cancer

Sialyl Lewis A (SLeA) is a tumor-associated carbohydrate antigen, also known as carbohydrate antigen 19-9 (CA19-9), that binds to E-selectin (ELAM-1) and selectins to mediate cell-endothelium adhesion. Sialyl Lewis A promotes cancer cell-vascular endothelium adhesion, and its surface presence correlates with increased tumorigenicity and invasiveness in cancer cells. Sialyl Lewis A shows elevated expression in human adenocarcinomas of the colon, pancreas, and stomach, with expression levels linked to tumor progression and poor prognosis in colorectal and gastric carcinomas. Sialyl Lewis A can be used for the research of cancers, such as colon, pancreas, stomach, and squamous lung cancer .
loading...
    loading...
Cat. No.: HY-N15141
CAS No.: 672-76-4
γ-Thujaplicin is a Hinokitiol (HY-B2230)-related compound that can be isolated from the wood of Thujopsis dolabrata. γ-Thujaplicin shows strong cytotoxic activities against human stomach cancer cell lines KATO-III and Ehrlich’s ascites carcinoma. γ-Thujaplicin exhibits potent and broad-spectrum antifungal activity on wood-rotting fungi, and insecticidal activity on the noxious insects. γ-Thujaplicin can be used for cancer and infection research and pest management .
loading...
    loading...
Cat. No.: HY-N21864
CAS No.: 1303438-53-0
Cathayanon J is a flavanone natural product with 2R configuration, which is found in the stem bark of Morus cathayana. Cathayanon J exhibits weak cytotoxicity against A549, Bel 7402, BGC-823, HCT-8 and A2780 human cancer cells, with IC50 values of 4.67, 5.95, 6.70, 5.86 and 5.79 μg/mL, respectively. Cathayanon J can be used in cancer-related research .
loading...
    loading...
Cat. No.: HY-N20646
CAS No.: 64703-85-1
Synonyms: Xiecaoiridoidside C
Kanokoside A (Xiecaoiridoidside C) is an iridoid glycoside that can be found in the roots of Centranthus longiflorus ssp. longiflorus, as well as the roots and rhizomes of Valeriana amurensis. Kanokoside A exhibits weak cytotoxicity against gastric cancer, liver cancer and breast cancer cells .
loading...
    loading...
Cat. No.: HY-N15140
CAS No.: 1946-74-3
α-Thujaplicin, the isomer of Hinokitiol (HY-B2230), is an antimicrobial agent. α-Thujaplicin can be isolated from Aomori Hiba (Thujopsis dolabrata SIEB. et ZUCC. var. hondai MAKINO). α-Thujaplicin shows inhibition of Carboxypeptidase A (IC50: 32.4 μM). α-Thujaplicin shows rather strong antifungal activity against seven kinds of plant-pathogenic fungi, their MICs being in the range of 12.0-50.0 μg/mL. α-Thujaplicin shows clear antibacterial activity against Legionella pneumophila SG 1 and L. pneumophila SG 3, and their MICs are in the range of 12.5-50 μg/mL. α-Thujaplicin shows antibacterial activity against Enterococcus faecalis IFO-12965 with a MIC of 1.56 μg/mL. α-Thujaplicin shows germination inhibition toward the seed of Echinochloa utilis Ohwi et Yabuno. α-thujaplicin inhibits lymphocytic leukemia, stomach cancer, Ehrlich’s ascites carcinoma .
loading...
    loading...
Cat. No.: HY-P992367

Target:  

TROP2

Research Areas:  

Cancer

hIMB1636 is a humanized monoclonal antibody targeting Trop2. By binding to the conformational Trop2 epitope, hIMB1636 regulates related signaling pathways, triggers lysosomal endocytosis, and further induces apoptosis, cell cycle arrest, and antibody-dependent cellular cytotoxicity. hIMB1636 effectively inhibits tumor cell proliferation, migration and in vivo tumor growth, and also exerts bystander killing effect and mediates long-term retention. hIMB1636 can be conjugated with NOTA/DOTA for radiolabeling to enable immuno-PET imaging, or prepared as hIMB1636-LDP-AE to significantly inhibit the growth of breast cancer and lung cancer xenografts .
loading...
    loading...