Cathayanon J
Cathayanon J is a flavanone natural product with 2R configuration, which is found in the stem bark of Morus cathayana. Cathayanon J exhibits weak cytotoxicity against A549, Bel 7402, BGC-823, HCT-8 and A2780 human cancer cells, with IC50 values of 4.67, 5.95, 6.70, 5.86 and 5.79 μg/mL, respectively. Cathayanon J can be used in cancer-related research.
For research use only. We do not sell to patients.
- CAS No.: 1303438-53-0
- Formula: C30H36O5
- Molecular Weight:476.60
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
4.67 μg/mL
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Cytotoxicity against human lung carcinoma A549 cells assessed by MTT assay following 4-day incubation.
Cytotoxicity against human lung carcinoma A549 cells assessed by MTT assay following 4-day incubation.
|
10286020.2010.489817 |
| Bel-7402 | IC50 |
5.95 μg/mL
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Cytotoxicity against human liver carcinoma Bel7402 cells assessed by MTT assay following 4-day incubation.
Cytotoxicity against human liver carcinoma Bel7402 cells assessed by MTT assay following 4-day incubation.
|
10286020.2010.489817 |
| BGC-823 | IC50 |
6.70 μg/mL
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Cytotoxicity against human stomach carcinoma BGC-823 cells assessed by MTT assay following 4-day incubation.
Cytotoxicity against human stomach carcinoma BGC-823 cells assessed by MTT assay following 4-day incubation.
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10286020.2010.489817 |
| HCT-8 | IC50 |
5.86 μg/mL
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Cytotoxicity against human colon carcinoma HCT-8 cells assessed by MTT assay following 4-day incubation.
Cytotoxicity against human colon carcinoma HCT-8 cells assessed by MTT assay following 4-day incubation.
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10286020.2010.489817 |
| A2780 | IC50 |
5.79 μg/mL
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Cytotoxicity against human ovarian carcinoma A2780 cells assessed by MTT assay following 4-day incubation.
Cytotoxicity against human ovarian carcinoma A2780 cells assessed by MTT assay following 4-day incubation.
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10286020.2010.489817 |
Cathayanon J (0.1-10.0 μg/mL; 4 days) exhibits cytotoxicity against human cancer cell lines A549, Bel 7402, BGC-823, HCT-8 and A2780, with IC50 values of 4.67, 5.95, 6.70, 5.86 and 5.79 μg/mL, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:human lung carcinoma (A549), human liver carcinoma (Bel7402), human stomach carcinoma (BGC-823), human colon carcinoma (HCT-8), human ovarian carcinoma (A2780)
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Concentration:0.1, 1.0, 10.0 μg/mL
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Incubation Time:4 days
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Result:Exhibited weak cytotoxic activity against human lung carcinoma (A549) cell line with an IC50 value of 4.67 μg/mL.
Exhibited weak cytotoxic activity against human liver carcinoma (Bel7402) cell line with an IC50 value of 5.95 μg/mL.
Exhibited weak cytotoxic activity against human stomach carcinoma (BGC-823) cell line with an IC50 value of 6.70 μg/mL.
Exhibited weak cytotoxic activity against human colon carcinoma (HCT-8) cell line with an IC50 value of 5.86 μg/mL.
Exhibited weak cytotoxic activity against human ovarian carcinoma (A2780) cell line with an IC50 value of 5.79 μg/mL.
Chemical Information
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CAS No. 1303438-53-0
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Molecular Weight 476.60
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Formula C30H36O5
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SMILES
O=C1C2=C(O)C=C(O)C=C2O[C@@H](C3=CC(C/C=C(C)/CC/C=C(C)\C)=C(C(C/C=C(C)\C)=C3)O)C1
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Cathayanon J Related Classifications
HY-N21864 Related Classifications
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