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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
structure elucidation
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "structure elucidation" in MCE Product Catalog:
Cat. No.: HY-142991
CAS No.: 185435-28-3
Synonyms: POPG
Target:
Research Areas:
8-Aminoadenine is an adenine receptor 1 (rAde1R) inhibitor with a Ki of 6.51 μM in rat and 0.0341 μM in human. 8-Aminoadenine inhibits isoprenaline-induced cAMP accumulation and adenine uptake in astrocytoma cells expressing rAde1R. 8-Aminoadenine serves as a lead structure for the development of adenine receptor ligands to elucidate the functions of the adenine receptor family .
Cat. No.: HY-D1409
Synonyms: DMTr-4'-F-uridine-CED-TBDMS phosphoramidite
Cat. No.: HY-N16542
CAS No.: 31489-30-2
Category:
Target:
Cat. No.: HY-N16580
CAS No.: 864452-88-0
Target:
Cat. No.: HY-N16836
CAS No.: 1559076-44-6
Synonyms: Farrerol 4',7-di-O-β-D-glucopyranoside
Target:
Cat. No.: HY-D1408
CAS No.: 1260508-74-4
Synonyms: DMTr-4'-Methyluridine-CED-TBDMS phosphoramidite
Cat. No.: HY-N12713
CAS No.: 20486-38-8
Category:
Flavonols Flavonoids Plants Orixa japonica Thunb. Salicaceae
Target:
Cat. No.: HY-N16533
CAS No.: 263368-92-9
Target:
Cat. No.: HY-125735
CAS No.: 877061-66-0
Category:
Target:
Cat. No.: HY-35034
CAS No.: 51576-04-6
Synonyms: (2S,3S)-2-Hydroxy-3-methylpentanoic acid
Research Areas:
L-Isoleucic acid ((2S,3S)-2-Hydroxy-3-methylpentanoic acid) ((S)-isoleucic acid) is a non-proteinogenic amino acid derivative. L-Isoleucic acid can be used as a key synthetic building block to construct JBIR-39 .
Cat. No.: HY-180463
CAS No.: 69282-19-5
Target:
Research Areas:
Rubradirin aglycone (Compound 7) is an aglycone of Rubradirin and can be obtained by mild acid hydrolysis of Rubradirin .
Cat. No.: HY-L248
858 compounds
The RNA-targeted bioactive compound library is a high-quality collection of small molecules specifically designed and curated to target RNA structures and functions. It is widely applied in cutting-edge drug discovery and life science research. Unlike traditional strategies that focus on protein targets, RNA-targeted compounds can directly modulate various functional RNA molecules by influencing their splicing, translation, stability, or structural conformation, thereby enabling precise intervention in key biological processes. In the field of drug development, these compounds provide a novel approach to addressing previously “undruggable” targets and have demonstrated significant potential in areas such as oncology, antiviral therapies, and neurodegenerative diseases. For example, by targeting disease-associated RNA structural domains or regulating the aberrant expression of non-coding RNAs, these compounds can effectively inhibit disease progression or restore normal cellular function. In mechanistic studies, RNA-targeted compounds serve as valuable chemical biology tools to elucidate the roles of RNA in gene expression regulation, cellular signaling pathways, and disease development.
The MCE RNA-targeted bioactive compound library contains 858 compounds, sourced from databases such as TargetRX Atlas and R-BIND. The library features excellent structural diversity and biological activity, making it suitable for high-throughput screening (HTS), target validation, phenotypic screening, and lead compound discovery. It represents a valuable resource for RNA-related research and innovative drug development.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
