structure elucidation

By Targets:	Amino Acid Derivatives (1) Bacterial (1) DNA Stain (2) Drug Intermediate (1) Drug Metabolite (1) Liposome (1) P2Y Receptor (1) Parasite (1) Phosphoramidites (2)
By Research Areas:	Cancer (1) Cardiovascular Disease (2) Infection (2) Metabolic Disease (1)
Oligonucleotides:	Phospholipids (1) Uracil (2) Phosphoramidites (2)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-142991

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol POPG	Liposome	Others
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol (POPG) is an anionic phosphatidylglycerol that often serves as a key component to co-construct model phospholipid bilayers with phosphatidylcholine (e.g., at a 3:1 POPC:POPG ratio) for investigating the structure and dynamics of transmembrane proteins. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol acts as a fundamental material for mimicking the physicochemical properties of biological membranes and enables the elucidation of membrane protein interaction mechanisms .

HY-103172

8-Aminoadenine	P2Y Receptor	Metabolic Disease
8-Aminoadenine is an adenine receptor 1 (rAde1R) inhibitor with a K_i of 6.51 μM in rat and 0.0341 μM in human. 8-Aminoadenine inhibits isoprenaline-induced cAMP accumulation and adenine uptake in astrocytoma cells expressing rAde1R. 8-Aminoadenine serves as a lead structure for the development of adenine receptor ligands to elucidate the functions of the adenine receptor family .

HY-D1409

DMTr-4'-F-U-CED-TBDMS phosphoramidite DMTr-4'-F-uridine-CED-TBDMS phosphoramidite	DNA Stain Phosphoramidites	Cardiovascular Disease
DMTr-4'-F-U-CED-TBDMS phosphoramidite (DMTr-4'-F-uridine-CED-TBDMS phosphoramidite), a dye reagent for oligonucleotide labeling, can be used for the research of applications in RNA therapeutics, RNA aptamers, and ribozymes for elucidating RNA structure. DMTr-4'-F-U-CED-TBDMS phosphoramidite represents a probe with wide utility for elucidation of RNA structure .

HY-N16580

(+)-Lariciresinol 9′-p-coumarate	Others	Cancer
(+)-Lariciresinol 9′-p-Coumarate is a type of lignan. (+)-Lariciresinol 9′-p-Coumarate exhibits inhibitory activity against leukemia and other tumor cell lines .

HY-N16542

n-Butylorsellinate	Parasite	Infection
N-Butylorsellinate is a butyl thicoline acid ester that can be found in fungi belonging to the Stereum genus. N-Butylorsellinate exhibits significant larvicide activity .

HY-N16836

Diplomorphanin A Farrerol 4',7-di-O-β-D-glucopyranoside	Others	Others
Diplomorphanin A (Farrerol 4',7-di-O-β-D-glucopyranoside) is a C-methylated flavonoid compound that can be found in Diplomorpha canescens. Diplomorpha canescens exhibits anti-tumor activity .

HY-D1408

DMTr-4'-Me-U-CED-TBDMS phosphoramidite DMTr-4'-Methyluridine-CED-TBDMS phosphoramidite	DNA Stain Phosphoramidites	Cardiovascular Disease
DMTr-4'-Me-U-CED-TBDMS phosphoramidite (DMTr-4'-Methyluridine-CED-TBDMS phosphoramidite), a dye reagent for oligonucleotide labeling, can be used for the research of applications in RNA therapeutics, RNA aptamers, and ribozymes for elucidating RNA structure. DMTr-4'-Me-U-CED-TBDMS phosphoramidite represents a probe with wide utility for elucidation of RNA structure .

HY-N12713

Flavoyadorinin A	Others	Others
Flavoyadorinin A is a type of flavonoid compound, and can be found in the Leaves of Viscum album Linnaeus var. coloratum Ohwi Epiphyting to Pyrus communis Linnaeus .

HY-N16533

4-(cis)-Acetyl-3,6,8-trihydroxy-3-methyldihydronaphthalenone	Others	Others
4-(cis)-Acetyl-3,6,8-trihydroxy-3-methyldihydronaphthalenone is a natural product that can be found in Senna siamea. 4-(cis)-Acetyl-3,6,8-trihydroxy-3-methyldihydronaphthalenone shows a very low affinity (K_i > 50 μM) in the adenosine A1 receptor binding test .

HY-125735

Sch725674	Bacterial	Infection
Sch725674 is a macrolide compound with antimicrobial activity against brewer's yeast and Candida albicans, with MICs of 8 and 32 μg/ml .

HY-35034

L-Isoleucic acid (2S,3S)-2-Hydroxy-3-methylpentanoic acid	Amino Acid Derivatives Drug Intermediate	Others
L-Isoleucic acid ((2S,3S)-2-Hydroxy-3-methylpentanoic acid) ((S)-isoleucic acid) is a non-proteinogenic amino acid derivative. L-Isoleucic acid can be used as a key synthetic building block to construct JBIR-39 .

HY-180463

Rubradirin aglycone	Drug Metabolite	Others
Rubradirin aglycone (Compound 7) is an aglycone of Rubradirin and can be obtained by mild acid hydrolysis of Rubradirin .

Cat. No.	Product Name

HY-L248

RNA Binding Bioactive Compound Library	854 compounds
The RNA-targeted bioactive compound library is a high-quality collection of small molecules specifically designed and curated to target RNA structures and functions. It is widely applied in cutting-edge drug discovery and life science research. Unlike traditional strategies that focus on protein targets, RNA-targeted compounds can directly modulate various functional RNA molecules by influencing their splicing, translation, stability, or structural conformation, thereby enabling precise intervention in key biological processes. In the field of drug development, these compounds provide a novel approach to addressing previously “undruggable” targets and have demonstrated significant potential in areas such as oncology, antiviral therapies, and neurodegenerative diseases. For example, by targeting disease-associated RNA structural domains or regulating the aberrant expression of non-coding RNAs, these compounds can effectively inhibit disease progression or restore normal cellular function. In mechanistic studies, RNA-targeted compounds serve as valuable chemical biology tools to elucidate the roles of RNA in gene expression regulation, cellular signaling pathways, and disease development. The MCE RNA-targeted bioactive compound library contains 854 compounds, sourced from databases such as TargetRX Atlas and R-BIND. The library features excellent structural diversity and biological activity, making it suitable for high-throughput screening (HTS), target validation, phenotypic screening, and lead compound discovery. It represents a valuable resource for RNA-related research and innovative drug development.

RNA Binding Bioactive Compound Library

854 compounds

The RNA-targeted bioactive compound library is a high-quality collection of small molecules specifically designed and curated to target RNA structures and functions. It is widely applied in cutting-edge drug discovery and life science research. Unlike traditional strategies that focus on protein targets, RNA-targeted compounds can directly modulate various functional RNA molecules by influencing their splicing, translation, stability, or structural conformation, thereby enabling precise intervention in key biological processes. In the field of drug development, these compounds provide a novel approach to addressing previously “undruggable” targets and have demonstrated significant potential in areas such as oncology, antiviral therapies, and neurodegenerative diseases. For example, by targeting disease-associated RNA structural domains or regulating the aberrant expression of non-coding RNAs, these compounds can effectively inhibit disease progression or restore normal cellular function. In mechanistic studies, RNA-targeted compounds serve as valuable chemical biology tools to elucidate the roles of RNA in gene expression regulation, cellular signaling pathways, and disease development.

The MCE RNA-targeted bioactive compound library contains 854 compounds, sourced from databases such as TargetRX Atlas and R-BIND. The library features excellent structural diversity and biological activity, making it suitable for high-throughput screening (HTS), target validation, phenotypic screening, and lead compound discovery. It represents a valuable resource for RNA-related research and innovative drug development.

Cat. No.	Product Name	Type

HY-D1409

DMTr-4'-F-U-CED-TBDMS phosphoramidite DMTr-4'-F-uridine-CED-TBDMS phosphoramidite	Fluorescent Dye
DMTr-4'-F-U-CED-TBDMS phosphoramidite (DMTr-4'-F-uridine-CED-TBDMS phosphoramidite), a dye reagent for oligonucleotide labeling, can be used for the research of applications in RNA therapeutics, RNA aptamers, and ribozymes for elucidating RNA structure. DMTr-4'-F-U-CED-TBDMS phosphoramidite represents a probe with wide utility for elucidation of RNA structure .

HY-D1408

DMTr-4'-Me-U-CED-TBDMS phosphoramidite DMTr-4'-Methyluridine-CED-TBDMS phosphoramidite	Fluorescent Dye
DMTr-4'-Me-U-CED-TBDMS phosphoramidite (DMTr-4'-Methyluridine-CED-TBDMS phosphoramidite), a dye reagent for oligonucleotide labeling, can be used for the research of applications in RNA therapeutics, RNA aptamers, and ribozymes for elucidating RNA structure. DMTr-4'-Me-U-CED-TBDMS phosphoramidite represents a probe with wide utility for elucidation of RNA structure .

Cat. No.	Product Name	Type

HY-142991

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol POPG	Biochemical Assay Reagents
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol (POPG) is an anionic phosphatidylglycerol that often serves as a key component to co-construct model phospholipid bilayers with phosphatidylcholine (e.g., at a 3:1 POPC:POPG ratio) for investigating the structure and dynamics of transmembrane proteins. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol acts as a fundamental material for mimicking the physicochemical properties of biological membranes and enables the elucidation of membrane protein interaction mechanisms .

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol

POPG

Biochemical Assay Reagents

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol (POPG) is an anionic phosphatidylglycerol that often serves as a key component to co-construct model phospholipid bilayers with phosphatidylcholine (e.g., at a 3:1 POPC:POPG ratio) for investigating the structure and dynamics of transmembrane proteins. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol acts as a fundamental material for mimicking the physicochemical properties of biological membranes and enables the elucidation of membrane protein interaction mechanisms .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N16580

(+)-Lariciresinol 9′-p-coumarate	Structural Classification Larix olgensis A. Henry Pinaceae Lignans Phenols Polyphenols Phenylpropanoids Plants Source Classification	Others
(+)-Lariciresinol 9′-p-Coumarate is a type of lignan. (+)-Lariciresinol 9′-p-Coumarate exhibits inhibitory activity against leukemia and other tumor cell lines .

HY-N16542

n-Butylorsellinate	Structural Classification Microorganisms Phenols Polyphenols Source Classification	Parasite
N-Butylorsellinate is a butyl thicoline acid ester that can be found in fungi belonging to the Stereum genus. N-Butylorsellinate exhibits significant larvicide activity .

HY-N16836

Diplomorphanin A Farrerol 4',7-di-O-β-D-glucopyranoside	Structural Classification Flavonoids Thymelaeaceae Plants Other Flavonoids Wikstroemia canescens (Wall.) Meisn. Source Classification	Others
Diplomorphanin A (Farrerol 4',7-di-O-β-D-glucopyranoside) is a C-methylated flavonoid compound that can be found in Diplomorpha canescens. Diplomorpha canescens exhibits anti-tumor activity .

HY-N12713

Flavoyadorinin A	Structural Classification Flavonols Flavonoids Plants Orixa japonica Thunb. Salicaceae Source Classification	Others
Flavoyadorinin A is a type of flavonoid compound, and can be found in the Leaves of Viscum album Linnaeus var. coloratum Ohwi Epiphyting to Pyrus communis Linnaeus .

HY-N16533

4-(cis)-Acetyl-3,6,8-trihydroxy-3-methyldihydronaphthalenone	Structural Classification Leguminosae Phenols Polyphenols Senna siamea (Lamarck) H. S. Irwin & Barneby Plants Source Classification	Others
4-(cis)-Acetyl-3,6,8-trihydroxy-3-methyldihydronaphthalenone is a natural product that can be found in Senna siamea. 4-(cis)-Acetyl-3,6,8-trihydroxy-3-methyldihydronaphthalenone shows a very low affinity (K_i > 50 μM) in the adenosine A1 receptor binding test .

HY-125735

Sch725674	Natural Products Microorganisms Source Classification	Bacterial
Sch725674 is a macrolide compound with antimicrobial activity against brewer's yeast and Candida albicans, with MICs of 8 and 32 μg/ml .

Cat. No.	Product Name		Classification

HY-142991

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol POPG		Phospholipids
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol (POPG) is an anionic phosphatidylglycerol that often serves as a key component to co-construct model phospholipid bilayers with phosphatidylcholine (e.g., at a 3:1 POPC:POPG ratio) for investigating the structure and dynamics of transmembrane proteins. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol acts as a fundamental material for mimicking the physicochemical properties of biological membranes and enables the elucidation of membrane protein interaction mechanisms .

HY-D1409

DMTr-4'-F-U-CED-TBDMS phosphoramidite DMTr-4'-F-uridine-CED-TBDMS phosphoramidite		Phosphoramidites Uracil
DMTr-4'-F-U-CED-TBDMS phosphoramidite (DMTr-4'-F-uridine-CED-TBDMS phosphoramidite), a dye reagent for oligonucleotide labeling, can be used for the research of applications in RNA therapeutics, RNA aptamers, and ribozymes for elucidating RNA structure. DMTr-4'-F-U-CED-TBDMS phosphoramidite represents a probe with wide utility for elucidation of RNA structure .

HY-D1408

DMTr-4'-Me-U-CED-TBDMS phosphoramidite DMTr-4'-Methyluridine-CED-TBDMS phosphoramidite		Phosphoramidites Uracil
DMTr-4'-Me-U-CED-TBDMS phosphoramidite (DMTr-4'-Methyluridine-CED-TBDMS phosphoramidite), a dye reagent for oligonucleotide labeling, can be used for the research of applications in RNA therapeutics, RNA aptamers, and ribozymes for elucidating RNA structure. DMTr-4'-Me-U-CED-TBDMS phosphoramidite represents a probe with wide utility for elucidation of RNA structure .

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
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structure elucidation

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

NaturalProducts

Oligonucleotides

Natural
Products