28128-33-8
28128-33-8
Chemical Structure
8-Aminoadenine
- CAS No.: 28128-33-8
- Formula:C5H6N6
- Molecular Weight:150.14
IUPAC Name: 9H-purine-6,8-diamine
InChIKey: PFUVOLUPRFCPMN-UHFFFAOYSA-N
SMILES: NC1=C2N=C(N)NC2=NC=N1
Biological Activity: 8-Aminoadenine is an adenine receptor 1 (rAde1R) inhibitor with a Ki of 6.51 μM in rat and 0.0341 μM in human. 8-Aminoadenine inhibits isoprenaline-induced cAMP accumulation and adenine uptake in astrocytoma cells expressing rAde1R. 8-Aminoadenine serves as a lead structure for the development of adenine receptor ligands to elucidate the functions of the adenine receptor family[1].
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8-Aminoadenine | 98.34% | 8-Aminoadenine is an adenine receptor 1 (rAde1R) inhibitor with a Ki of 6.51 μM in rat and 0.0341 μM in human. 8-Aminoadenine inhibits isoprenaline-induced cAMP accumulation and adenine uptake in astrocytoma cells expressing rAde1R. 8-Aminoadenine serves as a lead structure for the development of adenine receptor ligands to elucidate the functions of the adenine receptor family. | ||||||||||||||||||||
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References
Keywords
