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Results for "

teratogenicity and toxicity

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Aryl Hydrocarbon Receptor (1) Biochemical Assay Reagents (4) DNA/RNA Synthesis (1) Environmental Pollutants (3) Isotope-Labeled Compounds (3) Progesterone Receptor (3) Reference Standards (2)
By Research Areas:	Cancer (4) Endocrinology (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-Y1275

N-Methylpyrrolidone NMP; 1-Methyl-2-pyrrolidinone	Environmental Pollutants Biochemical Assay Reagents	Cancer
N-Methylpyrrolidone (1-Methyl-2-pyrrolidinone), a five-membered cyclic amide, is an orally active organic polar solvent with teratogenicity and toxicity. N-Methylpyrrolidone is low in acute toxicity with a LD₅₀ value of 3914 mg/kg in rats and of 4050 mg/kg in mice. N-Methylpyrrolidone is extensively used in the manufacture of adhesives, paints, fuels, and pharmaceuticals .

HY-W088065

Sodium formate	Environmental Pollutants DNA/RNA Synthesis	Others
Sodium formate acts as a key promoter for heterogeneous nucleation of ZIF crystals and thin film synthesis. It is also recognized as a GRAS substance by the FDA, and serves as a cosmetic preservative and food additive. Sodium formate has low acute oral toxicity (acute oral LD₅₀=7410 mg/kg and acute intravenous LD₅₀=807 mg/kg in mice), with no heritable or carcinogenic effects, but exhibits embryonic developmental toxicity and teratogenicity at high concentrations. Sodium formate may cause moderate irritation to rabbit eyes, is relatively safe to the skin, and does not induce tumor formation in rats in vivo. Sodium formate is rapidly absorbed and oxidized to carbon dioxide in vivo, and forms DNA adducts in specific metabolic deficiency models or upon high-dose exposure .

HY-75308

Azetidine-2-carboxylic acid 1 Publications Verification	Others	Cancer
Azetidine-2-carboxylic acid is a non proteinogenic amino acid homologue of proline. Found in common beets. Azetidine-2-carboxylic acid can be misincorporated into proteins in place of proline in many species, including humans. Toxic and teratogenic agent .

HY-B0742

Hydroxyprogesterone caproate Maximum Cited Publications 6 Publications Verification 17α-Hydroxyprogesterone hexanoate; 17α-Hydroxyprogesterone caproate	Progesterone Receptor	Endocrinology
Hydroxyprogesterone caproate (17α-Hydroxyprogesterone hexanoate; 17α-Hydroxyprogesterone caproate) is a progesterone receptor (progesterone receptor) ligand and steroid hormone transcription inhibitor. Hydroxyprogesterone caproate downregulates estrogen receptors in target tissues and activates their metabolic pathways, and exhibits equivalent affinity for progesterone receptor A and progesterone receptor B. Hydroxyprogesterone caproate shows no consistent teratogenicity or developmental toxicity in rat, mouse and monkey models, but induces resorption or abortion in rhesus monkeys at human-equivalent doses. Hydroxyprogesterone caproate promotes the production of TNF-α in lipopolysaccharide-stimulated whole blood from non-pregnant women. Hydroxyprogesterone caproate can be used in scientific research related to preterm birth .

HY-131551

Drometrizole	Environmental Pollutants Biochemical Assay Reagents	Others
Drometrizole is an orally active UV absorber and can be used in cosmetic research. Drometrizole has low acute toxicity, no teratogenicity and carcinogenicity .

HY-Y1275S

N-Methylpyrrolidone-d9 NMP-d₉; 1-Methyl-2-pyrrolidinone-d₉	Isotope-Labeled Compounds Biochemical Assay Reagents	Cancer
N-Methylpyrrolidone-d₉ (NMP-d₉) is deuterium labeled N-Methylpyrrolidone. N-Methylpyrrolidone (1-Methyl-2-pyrrolidinone), a five-membered cyclic amide, is an orally active organic polar solvent with teratogenicity and toxicity. N-Methylpyrrolidone is low in acute toxicity with a LD₅₀ value of 3914 mg/kg in rats and of 4050 mg/kg in mice. N-Methylpyrrolidone is extensively used in the manufacture of adhesives, paints, fuels, and pharmaceuticals .

HY-B0742R

Hydroxyprogesterone caproate (Standard) Maximum Cited Publications 6 Publications Verification 17α-Hydroxyprogesterone hexanoate(Standard); 17α-Hydroxyprogesterone caproate (Standard)	Reference Standards Progesterone Receptor	Others
Hydroxyprogesterone caproate (Standard) is the analytical standard of Hydroxyprogesterone caproate. This product is intended for research and analytical applications. Hydroxyprogesterone caproate (17α-Hydroxyprogesterone hexanoate; 17α-Hydroxyprogesterone caproate) is a progesterone receptor (progesterone receptor) ligand and steroid hormone transcription inhibitor. Hydroxyprogesterone caproate downregulates estrogen receptors in target tissues and activates their metabolic pathways, and exhibits equivalent affinity for progesterone receptor A and progesterone receptor B. Hydroxyprogesterone caproate shows no consistent teratogenicity or developmental toxicity in rat, mouse and monkey models, but induces resorption or abortion in rhesus monkeys at human-equivalent doses. Hydroxyprogesterone caproate promotes the production of TNF-α in lipopolysaccharide-stimulated whole blood from non-pregnant women. Hydroxyprogesterone caproate can be used in scientific research related to preterm birth .

HY-131551R

Drometrizole (Standard)	Biochemical Assay Reagents Reference Standards	Others
Drometrizole (Standard) is the analytical standard of Drometrizole (HY-131551). This product is intended for research and analytical applications. Drometrizole is an orally active UV absorber and can be used in cosmetic research. Drometrizole has low acute toxicity, no teratogenicity and carcinogenicity .

HY-170514

1,2,3,7,8,9-Hexachlorodibenzofuran	Aryl Hydrocarbon Receptor	Others
1,2,3,7,8,9-Hexachlorodibenzofuran is a polychlorinated dibenzofuran homologue. 1,2,3,7,8,9-Hexachlorodibenzofuran can interact with AhR. 1,2,3,7,8, 9-hexachlorodibenzofuran is highly toxic, teratogenic, carcinogenic and mutagenic .

HY-W746440

Azetidine-2-carboxylic acid-d4 D,L-Azetidine-2-carboxylic acid-d₄	Isotope-Labeled Compounds	Cancer
Azetidine-2-carboxylic acid-d₄ (D,L-Azetidine-2-carboxylic acid-d₄) is the deuterium labeled Azetidine-2-carboxylic acid (HY-75308). Azetidine-2-carboxylic acid is a non proteinogenic amino acid homologue of proline. Found in common beets. Azetidine-2-carboxylic acid can be misincorporated into proteins in place of proline in many species, including humans. Toxic and teratogenic agent .

HY-B0742S1

Hydroxyprogesterone caproate-d8 17α-Hydroxyprogesterone hexanoate-d₈; 17α-Hydroxyprogesterone caproate-d₈	Isotope-Labeled Compounds Progesterone Receptor	Others
Hydroxyprogesterone caproate-d₈ (17α-Hydroxyprogesterone hexanoate-d₈) is the deuterium labeled Hydroxyprogesterone caproate (HY-B0742). Hydroxyprogesterone caproate (17α-Hydroxyprogesterone hexanoate; 17α-Hydroxyprogesterone caproate) is a progesterone receptor (progesterone receptor) ligand and steroid hormone transcription inhibitor. Hydroxyprogesterone caproate downregulates estrogen receptors in target tissues and activates their metabolic pathways, and exhibits equivalent affinity for progesterone receptor A and progesterone receptor B. Hydroxyprogesterone caproate shows no consistent teratogenicity or developmental toxicity in rat, mouse and monkey models, but induces resorption or abortion in rhesus monkeys at human-equivalent doses. Hydroxyprogesterone caproate promotes the production of TNF-α in lipopolysaccharide-stimulated whole blood from non-pregnant women. Hydroxyprogesterone caproate can be used in scientific research related to preterm birth .

Cat. No.	Product Name	Type

HY-Y1275

N-Methylpyrrolidone NMP; 1-Methyl-2-pyrrolidinone	Biochemical Assay Reagents
N-Methylpyrrolidone (1-Methyl-2-pyrrolidinone), a five-membered cyclic amide, is an orally active organic polar solvent with teratogenicity and toxicity. N-Methylpyrrolidone is low in acute toxicity with a LD₅₀ value of 3914 mg/kg in rats and of 4050 mg/kg in mice. N-Methylpyrrolidone is extensively used in the manufacture of adhesives, paints, fuels, and pharmaceuticals .

HY-W088065

Sodium formate	Biochemical Assay Reagents
Sodium formate acts as a key promoter for heterogeneous nucleation of ZIF crystals and thin film synthesis. It is also recognized as a GRAS substance by the FDA, and serves as a cosmetic preservative and food additive. Sodium formate has low acute oral toxicity (acute oral LD₅₀=7410 mg/kg and acute intravenous LD₅₀=807 mg/kg in mice), with no heritable or carcinogenic effects, but exhibits embryonic developmental toxicity and teratogenicity at high concentrations. Sodium formate may cause moderate irritation to rabbit eyes, is relatively safe to the skin, and does not induce tumor formation in rats in vivo. Sodium formate is rapidly absorbed and oxidized to carbon dioxide in vivo, and forms DNA adducts in specific metabolic deficiency models or upon high-dose exposure .

Sodium formate

Biochemical Assay Reagents

Sodium formate acts as a key promoter for heterogeneous nucleation of ZIF crystals and thin film synthesis. It is also recognized as a GRAS substance by the FDA, and serves as a cosmetic preservative and food additive. Sodium formate has low acute oral toxicity (acute oral LD₅₀=7410 mg/kg and acute intravenous LD₅₀=807 mg/kg in mice), with no heritable or carcinogenic effects, but exhibits embryonic developmental toxicity and teratogenicity at high concentrations. Sodium formate may cause moderate irritation to rabbit eyes, is relatively safe to the skin, and does not induce tumor formation in rats in vivo. Sodium formate is rapidly absorbed and oxidized to carbon dioxide in vivo, and forms DNA adducts in specific metabolic deficiency models or upon high-dose exposure .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-75308

Azetidine-2-carboxylic acid 1 Publications Verification	Classification of Application Fields Amino acids Beta vulgaris Linn. Plants Disease Research Fields Cancer Source Classification Chenopodiaceae	Others
Azetidine-2-carboxylic acid is a non proteinogenic amino acid homologue of proline. Found in common beets. Azetidine-2-carboxylic acid can be misincorporated into proteins in place of proline in many species, including humans. Toxic and teratogenic agent .

Cat. No.	Product Name	Chemical Structure

HY-Y1275S

N-Methylpyrrolidone-d9
N-Methylpyrrolidone-d₉ (NMP-d₉) is deuterium labeled N-Methylpyrrolidone. N-Methylpyrrolidone (1-Methyl-2-pyrrolidinone), a five-membered cyclic amide, is an orally active organic polar solvent with teratogenicity and toxicity. N-Methylpyrrolidone is low in acute toxicity with a LD₅₀ value of 3914 mg/kg in rats and of 4050 mg/kg in mice. N-Methylpyrrolidone is extensively used in the manufacture of adhesives, paints, fuels, and pharmaceuticals .

N-Methylpyrrolidone-d9

N-Methylpyrrolidone-d₉ (NMP-d₉) is deuterium labeled N-Methylpyrrolidone. N-Methylpyrrolidone (1-Methyl-2-pyrrolidinone), a five-membered cyclic amide, is an orally active organic polar solvent with teratogenicity and toxicity. N-Methylpyrrolidone is low in acute toxicity with a LD₅₀ value of 3914 mg/kg in rats and of 4050 mg/kg in mice. N-Methylpyrrolidone is extensively used in the manufacture of adhesives, paints, fuels, and pharmaceuticals .

HY-W746440

Azetidine-2-carboxylic acid-d4
Azetidine-2-carboxylic acid-d₄ (D,L-Azetidine-2-carboxylic acid-d₄) is the deuterium labeled Azetidine-2-carboxylic acid (HY-75308). Azetidine-2-carboxylic acid is a non proteinogenic amino acid homologue of proline. Found in common beets. Azetidine-2-carboxylic acid can be misincorporated into proteins in place of proline in many species, including humans. Toxic and teratogenic agent .

HY-B0742S1

Hydroxyprogesterone caproate-d8
Hydroxyprogesterone caproate-d₈ (17α-Hydroxyprogesterone hexanoate-d₈) is the deuterium labeled Hydroxyprogesterone caproate (HY-B0742). Hydroxyprogesterone caproate (17α-Hydroxyprogesterone hexanoate; 17α-Hydroxyprogesterone caproate) is a progesterone receptor (progesterone receptor) ligand and steroid hormone transcription inhibitor. Hydroxyprogesterone caproate downregulates estrogen receptors in target tissues and activates their metabolic pathways, and exhibits equivalent affinity for progesterone receptor A and progesterone receptor B. Hydroxyprogesterone caproate shows no consistent teratogenicity or developmental toxicity in rat, mouse and monkey models, but induces resorption or abortion in rhesus monkeys at human-equivalent doses. Hydroxyprogesterone caproate promotes the production of TNF-α in lipopolysaccharide-stimulated whole blood from non-pregnant women. Hydroxyprogesterone caproate can be used in scientific research related to preterm birth .

Hydroxyprogesterone caproate-d8

Hydroxyprogesterone caproate-d₈ (17α-Hydroxyprogesterone hexanoate-d₈) is the deuterium labeled Hydroxyprogesterone caproate (HY-B0742). Hydroxyprogesterone caproate (17α-Hydroxyprogesterone hexanoate; 17α-Hydroxyprogesterone caproate) is a progesterone receptor (progesterone receptor) ligand and steroid hormone transcription inhibitor. Hydroxyprogesterone caproate downregulates estrogen receptors in target tissues and activates their metabolic pathways, and exhibits equivalent affinity for progesterone receptor A and progesterone receptor B. Hydroxyprogesterone caproate shows no consistent teratogenicity or developmental toxicity in rat, mouse and monkey models, but induces resorption or abortion in rhesus monkeys at human-equivalent doses. Hydroxyprogesterone caproate promotes the production of TNF-α in lipopolysaccharide-stimulated whole blood from non-pregnant women. Hydroxyprogesterone caproate can be used in scientific research related to preterm birth .

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teratogenicity and toxicity

Inhibitors & Agonists

Biochemical Assay Reagents

NaturalProducts

Isotope-Labeled Compounds

Natural
Products