12 Results for "

type A GABA receptors

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "type A GABA receptors" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-113413
CAS No.: 645-65-8
Purity:  99.56%
Synonyms: Imidazolyl-4-acetic acid
Imidazoleacetic acid (Imidazolyl-4-acetic acid) is a blood-brain barrier-permeable full agonist of the GABAA receptor. Imidazoleacetic acid forms via histamine oxidation in the mouse brain. Imidazoleacetic acid exerts multiple neurochemical and behavioral effects. Imidazoleacetic acid induces a range of centrally mediated effects, including analgesia, sedation, hypnosis, as well as reductions in blood pressure, body temperature, isolation-induced aggression and motor activity .
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Cat. No.: HY-121618
CAS No.: 546-80-5
Purity:  98.07%
α-Thujone is a monoterpene isolated from Thuja occidentalis essential oil with potent anti-tumor activities. α-Thujone is a reversible modulator of the GABA type A receptor and the IC50 for α-Thujone is 21 μM in suppressing the GABA-induced currents. α-Thujone induces ROS accumulation-dependent cytotoxicity, also induces cell apoptosis and autophagy. α-Thujone has antinociceptive, insecticidal, and anthelmintic activity, and can cross the blood-brain barrier .
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Cat. No.: HY-B0340
CAS No.: 77191-36-7
Synonyms: DM9384; DZL-221
Nefiracetam is a cognition-enhancing agent. Nefiracetam is an activator of nAChR, N-methyl-D-aspartate receptor (NMDAR), mGluR5, PKC, gamma-aminobutyric acid (GABA), and N/L-type Ca 2+ channels. Nefiracetam promotes neuroplasticity and enhances neuroprotection. Nefiracetam can be used in Alzheimer's disease, epilepsy, and cerebral ischemia research .
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Cat. No.: HY-W743398
CAS No.: 31868-18-5
Synonyms: CS-386
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

Mexazolam (CS-386) is an orally active benzodiazepine and anxiolytic. Benzodiazepines bind to specific BZD-type receptors on the GABA-chloride complex and potentiate the inhibitory effects of GABA .
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Cat. No.: HY-W050122
CAS No.: 7013-05-0
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

S-(+)-GABOB is an endogenous ligand with antiepileptic activity. S-(+)-GABOB is a metabolite of GABA and may function as a neurotransmitter. S-(+)-GABOB behaves as a full agonist when bound to the ρ(1) wild-type receptor. S-(+)-GABOB acts as a competitive antagonist in the ρ(1) T244S mutant receptor .
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Cat. No.: HY-A0198
CAS No.: 37115-32-5
Synonyms: U 41123
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

Adinazolam (U 41123) is a triazolobenzodiazepine. Adinazolam binds to peripheral-type benzodiazepine receptors which interact allosterically with GABA receptors. Adinazolam has dual anxiolytic and antidepressant activities .
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Cat. No.: HY-A0198A
CAS No.: 57938-82-6
Synonyms: U 41123F mesylate
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

Adinazolam (U 41123F) mesylate is a triazolobenzodiazepine. Adinazolam mesylate binds to peripheral-type benzodiazepine receptors which interact allosterically with GABA receptors. Adinazolam mesylate has dual anxiolytic and antidepressant activities .
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Cat. No.: HY-19006
CAS No.: 83910-34-3
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

ZK-91296 is a GABA receptor agonist with anxiolytic activity. ZK-91296 can reduce anxiety in animals without causing sedation. ZK-91296 may have pharmacological selectivity for interaction with specific types of benzodiazepine receptors .
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Cat. No.: HY-A0198S
Synonyms: U 41123-d5
Adinazolam-d5 (U 41123-d5) is a deuterium labeled Adinazolam (HY-A0198). Adinazolam is a triazolobenzodiazepine. Adinazolam binds to peripheral-type benzodiazepine receptors which interact allosterically with GABA receptors. Adinazolam has dual anxiolytic and antidepressant activities .
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Cat. No.: HY-B0340R
CAS No.: 77191-36-7
Synonyms: DM9384 (Standard); DZL-221 (Standard)
Nefiracetam (Standard) is a cognition-enhancing agent. Nefiracetam is an activator of nAChR, N-methyl-D-aspartate receptor (NMDAR), mGluR5, PKC, gamma-aminobutyric acid (GABA), and N/L-type Ca 2+ channels. Nefiracetam promotes neuroplasticity and enhances neuroprotection. Nefiracetam can be used in Alzheimer's disease, epilepsy, and cerebral ischemia research .
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Cat. No.: HY-121618R
CAS No.: 546-80-5
α-Thujone (Standard) is the analytical standard of α-Thujone. This product is intended for research and analytical applications. α-Thujone is a monoterpene isolated from Thuja occidentalis essential oil with potent anti-tumor activities. α-Thujone is a reversible modulator of the GABA type A receptor and the IC50 for α-Thujone is 21 μM in suppressing the GABA-induced currents. α-Thujone induces ROS accumulation-dependent cytotoxicity, also induces cell apoptosis and autophagy. α-Thujone has antinociceptive, insecticidal, and anthelmintic activity, and easily penetrates the blood-brain barrier .
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Cat. No.: HY-182511
CAS No.: 2188230-70-6
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

IUN-00433 (Compound 36) is a selective positive allosteric modulator of α4β1δ-type GABAA receptors, with an EC50 of 0.060 μM. IUN-00433 is applicable to research related to neurological disorders .
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