α-Thujone (Standard)
α-Thujone (Standard) is the analytical standard of α-Thujone. This product is intended for research and analytical applications. α-Thujone is a monoterpene isolated from Thuja occidentalis essential oil with potent anti-tumor activities. α-Thujone is a reversible modulator of the GABA type A receptor and the IC50 for α-Thujone is 21 μM in suppressing the GABA-induced currents. α-Thujone induces ROS accumulation-dependent cytotoxicity, also induces cell apoptosis and autophagy. α-Thujone has antinociceptive, insecticidal, and anthelmintic activity, and easily penetrates the blood-brain barrier.
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- CAS No.: 546-80-5
- Formule: C10H16O
- Masse moléculaire:152.24
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Pureté et documentation
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Help & FAQs
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HY-121618
α-ThujoneGABA Receptor Modulator -
HY-B0355
Ginkgolide AGABA Antagonist -
HY-N0110
Palmatine chlorideIDO-1/NS2B-NS3 Inhibitor -
HY-B0355R
Ginkgolide A (Standard) -
HY-N1401
20(R)-Ginsenoside Rh2Anti-tumor/Anti-viral/Anti-inflammatory Agent -
HY-107198
(2S)-6-PrenylnaringeninGABAA PAM -
HY-N0110R
Palmatine chloride (Standard)IDO-1/NS2B-NS3 Inhibitor -
HY-N1401R
20(R)-Ginsenoside Rh2 (Standard)Standard of 20(R)-Ginsenoside Rh2
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 546-80-5
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Masse moléculaire 152.24
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Formule C10H16O
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SMILES
O=C1C[C@]2(C(C)C)C[C@]2([H])[C@H]1C
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Agus HH, et al. Involvement of Pca1 in ROS-mediated apoptotic cell death induced by alpha-thujone in the fission yeast (Schizosaccharomyces pombe). FEMS Yeast Res. 2020 Apr 29. pii: foaa022. [Content Brief]
[2]. Pudełek M, et al. Therapeutic potential of monoterpene α-thujone, the main compound of Thuja occidentalis L. essential oil, against malignant glioblastoma multiforme cells in vitro. Fitoterapia. 2019 Apr;134:172-181. [Content Brief]
[3]. Höld KM, et al. Alpha-thujone (the active component of absinthe): gamma-aminobutyric acid type A receptor modulation and metabolic detoxification. Proc Natl Acad Sci U S A. 2000 Apr 11;97(8):3826-31. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
α-Thujone (Standard) Related Classifications
HY-121618R Related Classifications
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