HSP70-IN-9
HSP70-IN-9 is a Hsp70 inhibitor. HSP70-IN-9 activates Caspase-3 and -7. HSP70-IN-9 exerts anticancer effects against acute myeloid leukemia. HSP70-IN-9 can be used for the research of acute myeloid leukemia.
For research use only. We do not sell to patients.
- CAS No.: 1268273-85-3
- Formula: C23H26N6OS
- Molecular Weight:434.56
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Caspase Isoforms
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Biological Activity
|
Caspase 3 |
Caspase-7 |
HSP70 |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Kasumi 1 | IC50 |
20.8 μM
Compound: 27g
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Cytotoxicity against human Kasumi-1 cells after 72 hrs by alamar blue assay
Cytotoxicity against human Kasumi-1 cells after 72 hrs by alamar blue assay
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[PMID: 24548239] |
HSP70-IN-9 (Compound 27g) inhibits the growth of Kasumi-1 acute myeloid leukemia cells with an IC50 of 20.8 μM[1].
HSP70-IN-9 induces caspase-3,-7 activation in MOLM13 acute myeloid leukemia cells with an IC50 of 25.2 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1268273-85-3
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Appearance Solid
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Molecular Weight 434.56
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Formula C23H26N6OS
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Color White to light yellow
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SMILES
O=C(CN)NC1=CC(SC2=CN=C(N3CCN(CC3)C)N=C2C4=CC=CC=C4)=CC=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HSP70-IN-9 Related Classifications
HY-184106 Related Classifications
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