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United States

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Referencia número: HY-117248

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SR-3737

SR-3737 is a JNK3 and p38 inhibitor (IC₅₀: 12 and 3 nM).

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No. CAS: 1164153-37-0
Fòrmula: C₂₉H₂₅FN₄O₄
Peso molecular:512.53

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

SR-3737 Chemical Structure

No. CAS: 1164153-37-0

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

SR-3737 is a JNK3 and p38 inhibitor (IC₅₀: 12 and 3 nM)^[1].

Ver todos los productos específicos de isoformas JNK :

Ver todos los productos específicos de isoformas p38 MAPK :

Chemical Information

No. CAS 1164153-37-0
Peso molecular 512.53
Fòrmula C₂₉H₂₅FN₄O₄
SMILES

O=C(NC1=CC(OC)=C(OC)C(OC)=C1)C2=CC=CC(N3N=CC4=C3C=CC(NC5=CC=CC=C5F)=C4)=C2
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Kamenecka T, et al. Structure-activity relationships and X-ray structures describing the selectivity of aminopyrazole inhibitors for c-Jun N-terminal kinase 3 (JNK3) over p38. J Biol Chem. 2009 May 8;284(19):12853-61. [Content Brief]

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Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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SR-3737

Ver todos los productos específicos de isoformas JNK

Ver todos los productos específicos de isoformas p38 MAPK

Actividad biológica

Descripciòn

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

SR-3737 Related Classifications

HY-117248 Related Classifications

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