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  4. Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium

Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium 

Cat. No.: HY-139722
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Tenofovir-C3-O-C12-trimethylsilylacetylene (ammonium) exhibits substantially longer t1/2 values than tenofovir in human liver microsomes, potent anti-HIV activity in vitro, and enhances pharmacokinetic properties in vivo. Tenofovir-C3-O-C12-trimethylsilylacetylene (ammonium) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium

Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium 화학구조

CAS No. : 2611373-74-9

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Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium Related Antibodies

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제품 설명

Tenofovir-C3-O-C12-trimethylsilylacetylene (ammonium) exhibits substantially longer t1/2 values than tenofovir in human liver microsomes, potent anti-HIV activity in vitro, and enhances pharmacokinetic properties in vivo. Tenofovir-C3-O-C12-trimethylsilylacetylene (ammonium) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cellular Effect
Cell Line Type Value Description References
HEK-293T CC50
> 100 μM
Compound: 23
Cytotoxicity against HEK293T cells assessed as reduction in cell viability measured after 48 hrs by CellTiter 96 Aqueous One Solution reagent based cell proliferation assay
Cytotoxicity against HEK293T cells assessed as reduction in cell viability measured after 48 hrs by CellTiter 96 Aqueous One Solution reagent based cell proliferation assay
[PMID: 34459598]
분자량

626.84

화학식

C29H55N6O5PSi
CAS No.
SMILES

C[Si](C)(C)C#CCCCCCCCCCCCCOCCCOP(CO[C@H](C)CN1C2=NC=NC(N)=C2N=C1)([O-])=O.[NH4+]
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
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Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tenofovir-C3-O-C12-trimethylsilylacetylene2611373-74-9HIVHuman immunodeficiency virusInhibitorinhibitorinhibit

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Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium
Cat. No.:
HY-139722
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