Thalidomide-NH-C9-NH2 hydrochloride

Cat. No.: HY-156159 Purity: 99.85%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Thalidomide-NH-C9-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein.Thalidomide-NH-C9-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Thalidomide-NH-C9-NH2 hydrochloride 화학구조

CAS No. : 2305936-77-8

사이즈	재고	수량
5 mg	해외재고보유	Estimated Time of Arrival: December 31
10 mg	해외재고보유	Estimated Time of Arrival: December 31
25 mg	해외재고보유	Estimated Time of Arrival: December 31
50 mg	해외재고보유	Estimated Time of Arrival: December 31
100 mg	견적 받기
200 mg	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 publication(s) in Google Scholar

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von Hippel-Lindau (VHL) MDM2 Cereblon cIAP1 Aryl Hydrocarbon Receptor TRIM21

Biological Activity
순도&문서
References
고객리뷰

제품 설명

IC₅₀ & Target

Cereblon

분자량

450.96

화학식

C₂₂H₃₁ClN₄O₄

CAS No.

2305936-77-8

Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCCCCCCCCN)=CC=C3)=O)=O.Cl

선적

Room temperature in continental US; may vary elsewhere.

보관

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

순도&문서

Purity: 99.85%

Select Batch:

Data Sheet (268 KB) SDS (418 KB)

COA (249 KB) HNMR (218 KB) LCMS (96 KB)

Handling Instructions (2659 KB)

References

[1]. Fischer ES, et al. Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide. Nature. 2014 Aug 7;512(7512):49-53. [Content Brief] [Content Brief]