Val-Ala-PABC-Exatecan trifluoroacetate
Based on 1 publication(s) in Google Scholar
Val-Ala-PABC-Exatecan trifluoroacetate is a Drug-Linker Conjugates for ADC, consiting of a cleavable Tesirine linker (Val-Ala-PABC) and Exatecan (topoisomerase I inhibitor, HY-13631). Val-Ala-PABC-Exatecan trifluoroacetate can be used for ADC molecues synthesis, such as Mal-PEGn-amide-va-Exatecan.
For research use only. We do not sell to patients.
- Purity: 98.39%
- CAS No.: 2928571-45-1
- Formula: C42H44F4N6O10
- Molecular Weight:868.83
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Val-Ala-PABC-Exatecan trifluoroacetate
MoreAll Drug-Linker Conjugates for ADC Isoforms
MoreAll Topoisomerase Isoforms
More
Biological Activity
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Camptothecins |
Chemical Information
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CAS No. 2928571-45-1
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Appearance Solid
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Molecular Weight 868.83
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Formula C42H44F4N6O10
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Color Light yellow to yellow
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SMILES
CC[C@]1(C(OCC2=C1C=C3C4=NC5=CC(F)=C(C6=C5C([C@H](CC6)NC(OCC7=CC=C(C=C7)NC([C@@H](NC([C@H](C(C)C)N)=O)C)=O)=O)=C4CN3C2=O)C)=O)O.OC(C(F)(F)F)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (1)
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Journal Impact Factor
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Most Recent
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Res Sq
Development of a STEAP1-Targeted Prostate Cancer Specific Antibody Drug Conjugate Platform with Immunostimulatory Properties. [Abstract]2026 Apr 24:rs.3.rs-9194287. PMID: 42078873
Solvent & Solubility
DMSO : 50 mg/mL (57.55 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (279 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1510 mL | 5.7549 mL | 11.5097 mL | 28.7743 mL |
| 5 mM | 0.2302 mL | 1.1510 mL | 2.3019 mL | 5.7549 mL | |
| 10 mM | 0.1151 mL | 0.5755 mL | 1.1510 mL | 2.8774 mL | |
| 15 mM | 0.0767 mL | 0.3837 mL | 0.7673 mL | 1.9183 mL | |
| 20 mM | 0.0575 mL | 0.2877 mL | 0.5755 mL | 1.4387 mL | |
| 25 mM | 0.0460 mL | 0.2302 mL | 0.4604 mL | 1.1510 mL | |
| 30 mM | 0.0384 mL | 0.1918 mL | 0.3837 mL | 0.9591 mL | |
| 40 mM | 0.0288 mL | 0.1439 mL | 0.2877 mL | 0.7194 mL | |
| 50 mM | 0.0230 mL | 0.1151 mL | 0.2302 mL | 0.5755 mL |
Val-Ala-PABC-Exatecan trifluoroacetate Related Classifications
HY-147095A Related Classifications
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