Vonoprazan Fumarate (Standard)
Based on 1 Customer Validation
Vonoprazan (Fumarate) (Standard) is the analytical standard of Vonoprazan (Fumarate). This product is intended for research and analytical applications. Vonoprazan Fumarate (TAK-438), a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB), with antisecretory activity. Vonoprazan Fumarate inhibits H+,K+-ATPase activity in porcine gastric microsomes with an IC50 of 19 nM at pH 6.5. Vonoprazan Fumarate is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease.
For research use only. We do not sell to patients.
- CAS No.: 881681-01-2
- Formula: C21H20FN3O6S
- Molecular Weight:461.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
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HY-15295
Vonoprazan Fumarate
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HY-17507
Pantoprazole
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HY-17421
Tenatoprazole
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HY-17507R
Pantoprazole (Standard)
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HY-N6771
Cyclopiazonic acid
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HY-B0572
Zinc Pyrithione
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HY-101664
Ilaprazole
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HY-13662C
(S)-Lansoprazole
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HY-17421R
Tenatoprazole (Standard)
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HY-B0572R
Zinc Pyrithione (Standard)
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HY-N6771R
Cyclopiazonic acid (Standard)
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HY-101664R
Ilaprazole (Standard)
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 881681-01-2
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Appearance Solid
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Molecular Weight 461.46
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Formula C21H20FN3O6S
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Color White to off-white
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SMILES
OC(/C=C/C(O)=O)=O.O=S(N1C(C2=C(C=CC=C2)F)=CC(CNC)=C1)(C3=CN=CC=C3)=O
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Synonyms
TAK-438 (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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SDS (420 KB)
- English - EN (420 KB)
- Français - FR (420 KB)
- Deutsch - DE (420 KB)
- Norwegian - NO (420 KB)
- Español - ES (420 KB)
- Swedish - SV (420 KB)
- Italian - IT (420 KB)
- Korean - KR (420 KB)
- Portuguese - PT (420 KB)
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Handling Instructions (2659 KB)
References
[1]. Arikawa Y, et al. Discovery of a novel pyrrole derivative 1-[5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine fumarate (TAK-438) as a potassium-competitive acid blocker (P-CAB). J Med Chem, 2012, 55(9), 4446-4456. [Content Brief]
[2]. Hori Y, et al. 1-[5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine monofumarate (TAK-438), a novel and potent potassium-competitive acid blocker for the treatment of acid-related diseases. J Pharmacol Exp Ther, 2010, 335(1), 231-238. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Vonoprazan Fumarate (Standard) Related Classifications
HY-15295R Related Classifications
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