α-Triglycidyl isocyanurate
α-Triglycidyl isocyanurate (Teroxirone) is an antitumor compound with activity to inhibit DNA replication. α-Triglycidyl isocyanurate exerts its anticancer effect by alkylating and cross-linking DNA. α-Triglycidyl isocyanurate is relatively stable in fresh human plasma and whole blood, showing good biocompatibility. The metabolism of α-Triglycidyl isocyanurate mainly occurs in rat liver and is metabolized through an NADPH-independent pathway. The cytotoxicity of α-Triglycidyl isocyanurate can be partially restored under specific conditions, suggesting the complexity of its metabolic pathway.
For research use only. We do not sell to patients.
- CAS No.: 59653-73-5
- Formula: C12H15N3O6
- Molecular Weight:297.26
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Endogenous Metabolite Isoforms
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Biological Activity
Chemical Information
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CAS No. 59653-73-5
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Molecular Weight 297.26
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Formula C12H15N3O6
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SMILES
O=C(N(C(N(C1=O)C[C@H]2CO2)=O)C[C@@H]3CO3)N1C[C@@H]4CO4
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Synonyms
Teroxirone
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)