(αR,8aS)-GSK1614343

製品番号: HY-113906A 純度: 99.72%: Data Sheet SDS COA 取扱説明書
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(αR,8aS)-GSK1614343 is the isomer of GSK1614343 (HY-113906). GSK1614343 is the potent antagonist of growth hormone secretagogues type 1a (GHS1a) receptors.

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(αR,8aS)-GSK1614343 構造式

CAS 番号 : 1092476-84-0

容量	価格（税別）	在庫状況	数量

>無料サンプル (0.1 - 0.2 mg)		今すぐ申し込む
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 107	在庫あり	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 107	在庫あり	Estimated Time of Arrival: December 31
Solid
5 mg	$100	在庫あり	Estimated Time of Arrival: December 31
10 mg	$160	在庫あり	Estimated Time of Arrival: December 31
25 mg	$320	在庫あり	Estimated Time of Arrival: December 31
50 mg	$500	在庫あり	Estimated Time of Arrival: December 31
100 mg	$800	在庫あり	Estimated Time of Arrival: December 31
200 mg		お問い合わせ
500 mg		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 1 publication(s) in Google Scholar

Other Forms of (αR,8aS)-GSK1614343:

GSK1614343 お問い合わせ

GHSR アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

GHSR1a

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

(αR,8aS)-GSK1614343 is the isomer of GSK1614343 (HY-113906). GSK1614343 is the potent antagonist of growth hormone secretagogues type 1a (GHS1a) receptors^[1].

分子量

487.44

分子式

C₂₂H₂₃F₆N₅O

CAS 番号

1092476-84-0

Appearance

Solid

Color

White to off-white

SMILES

FC(F)(F)C1=CC(C(F)(F)F)=CC(NNC([C@@H](C2=CN=CC=C2)N3C[C@@]4([H])N(CCC4)CC3)=O)=C1

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

溶剤 & 溶解度

体外:

DMSO : 100 mg/mL (205.15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.0515 mL	10.2577 mL	20.5153 mL
5 mM	0.4103 mL	2.0515 mL	4.1031 mL
10 mM	0.2052 mL	1.0258 mL	2.0515 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

純度とドキュメンテーション

純度: 99.72%

Select Batch:

データシート (273 KB) SDS (252 KB)

COA (255 KB) HNMR (270 KB) RP-HPLC (261 KB) LCMS (103 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Perdonà E, et al. Pharmacological characterization of the ghrelin receptor antagonist, GSK1614343 in rat RC-4B/C cells natively expressing GHS type 1a receptors. Eur J Pharmacol. 2011;650(1):178-183. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.0515 mL	10.2577 mL	20.5153 mL	51.2884 mL
	5 mM	0.4103 mL	2.0515 mL	4.1031 mL	10.2577 mL
	10 mM	0.2052 mL	1.0258 mL	2.0515 mL	5.1288 mL
	15 mM	0.1368 mL	0.6838 mL	1.3677 mL	3.4192 mL
	20 mM	0.1026 mL	0.5129 mL	1.0258 mL	2.5644 mL
	25 mM	0.0821 mL	0.4103 mL	0.8206 mL	2.0515 mL
	30 mM	0.0684 mL	0.3419 mL	0.6838 mL	1.7096 mL
	40 mM	0.0513 mL	0.2564 mL	0.5129 mL	1.2822 mL
	50 mM	0.0410 mL	0.2052 mL	0.4103 mL	1.0258 mL
	60 mM	0.0342 mL	0.1710 mL	0.3419 mL	0.8548 mL
	80 mM	0.0256 mL	0.1282 mL	0.2564 mL	0.6411 mL
	100 mM	0.0205 mL	0.1026 mL	0.2052 mL	0.5129 mL