γ-glutamyltransferase, Porcine kidney
Based on 1 publication(s) in Google Scholar
γ-glutamyltransferase, Porcine kidney (GGT, Porcine kidney) is an enzyme located on the outer surface of the cell membrane. γ-glutamyltransferase, Porcine kidney maintains the physiological concentration of cytoplasmic glutathione and the cell's defense against oxidative stress by cleaving extracellular glutathione and increasing the availability of amino acids. γ-glutamyltransferase, Porcine kidney is used for pancreatic cancer research.
For research use only. We do not sell to patients.
- CAS No.: 9046-27-9
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) γ-glutamyltransferase, Porcine kidney
MoreAll Endogenous Metabolite Isoforms
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Biological Activity
Description
In Vitro
Iso-peptide hydrolysis
1 μg of tubulin was incubated with 1 U of γ-glutamyltransferase and 10 mM Gly-Gly peptide in 65 μL of 50 mM Tris/Cl, pH 8.0 (containing 150 mM NaCl) at 37 °C for 22 h.
γ-glutamyltransferase, Porcine kidney co-incubated with GSAO serves as a positive control to demonstrate the conversion of GSAO to GCAO[3].
γ-glutamyltransferase, Porcine kidney shows properties similar to those of the renal enzyme in LLC-PK1 cells, and its activity increases with cell density[4].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
EC Number
2.3.2.2
Enzyme Activity
≥20 U/mg soild
Unit Definition
One unit is defined as the amount of enzyme that will release 1.0 μmol of p-nitroaniline from L-γglutamyl-β-nitroaniline per minute at 25°C and pH 8.5
Chemical Information
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CAS No. 9046-27-9
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Appearance Solid
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Color White to off-white
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SMILES
[g-glutamyltransferase, Porcine kidney]
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Synonyms
GGT, Porcine kidney
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Anal Chem
2025 Jul 22;97(28):15393-15401. PMID: 40557718
Purity & Documentation
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Data Sheet (269 KB)
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SDS (557 KB)
- English - EN (557 KB)
- Français - FR (557 KB)
- Deutsch - DE (557 KB)
- Norwegian - NO (557 KB)
- Español - ES (557 KB)
- Swedish - SV (557 KB)
- Italian - IT (557 KB)
- Korean - KR (557 KB)
- Portuguese - PT (557 KB)
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Handling Instructions (2659 KB)
References
[1]. Whitfield JB. Gamma glutamyl transferase. Crit Rev Clin Lab Sci. 2001 Aug;38(4):263-355. [Content Brief]
[3]. Ramsay EE, et al. Employing pancreatic tumor γ-glutamyltransferase for therapeutic delivery. Mol Pharm. 2014 May 5;11(5):1500-11. [Content Brief]
[4]. Sepúlveda FV, et al. The development of gamma-glutamyltransferase in a pig renal-epithelial-cell line in vitro. Relationship to amino acid transport. Biochem J. 1982 Nov 15;208(2):509-12. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
γ-glutamyltransferase, Porcine kidney Related Classifications
HY-P2997 Related Classifications
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