9046-27-9
Chemical Structure
γ-glutamyltransferase, Porcine kidney
Synonym(s): GGT, Porcine kidney
- CAS No.: 9046-27-9
- Formula:N/A
- Molecular Weight:N/A
InChIKey: VNWKTOKETHGBQD-UHFFFAOYSA-N
SMILES: [g-glutamyltransferase, Porcine kidney]
Biological Activity: γ-glutamyltransferase, Porcine kidney (GGT, Porcine kidney) is an enzyme located on the outer surface of the cell membrane. γ-glutamyltransferase, Porcine kidney maintains the physiological concentration of cytoplasmic glutathione and the cell's defense against oxidative stress by cleaving extracellular glutathione and increasing the availability of amino acids. γ-glutamyltransferase, Porcine kidney is used for pancreatic cancer research[1][2][3][4].
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γ-glutamyltransferase, Porcine kidney | γ-glutamyltransferase, Porcine kidney (GGT, Porcine kidney) is an enzyme located on the outer surface of the cell membrane. γ-glutamyltransferase, Porcine kidney maintains the physiological concentration of cytoplasmic glutathione and the cell's defense against oxidative stress by cleaving extracellular glutathione and increasing the availability of amino acids. γ-glutamyltransferase, Porcine kidney is used for pancreatic cancer research. | |||||||||||||||||||||
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γ-glutamyltransferase, Human | γ-glutamyltransferase, Human participates in glutathione metabolism. Serum γ-glutamyltransferase activity is identified as a predictor of atherosclerotic complications, and has prognostic value for cardiovascular diseases and stroke. γ-glutamyltransferase also serves as a biomarker for carcinogenesis and tumor progression. | |||||||||||||||||||||
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- [1]. Whitfield JB. Gamma glutamyl transferase. Crit Rev Clin Lab Sci. 2001 Aug;38(4):263-355. [Content Brief]
- [2]. G Ndrepepa, et al. "Gamma-glutamyl transferase and cardiovascular disease." Annals of translational medicine 4.24 (2016).
- [3]. Ramsay EE, et al. Employing pancreatic tumor γ-glutamyltransferase for therapeutic delivery. Mol Pharm. 2014 May 5;11(5):1500-11. [Content Brief]
- [4]. Sepúlveda FV, et al. The development of gamma-glutamyltransferase in a pig renal-epithelial-cell line in vitro. Relationship to amino acid transport. Biochem J. 1982 Nov 15;208(2):509-12. [Content Brief]