1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite

3-Methyl-2-oxobutanoic acid 

Cat. No.: HY-W006057 Purity: >97.0%
Handling Instructions

3-Methyl-2-oxobutanoic acid is a precursor of pantothenic acid in Escherichia coli.

For research use only. We do not sell to patients.

3-Methyl-2-oxobutanoic acid Chemical Structure

3-Methyl-2-oxobutanoic acid Chemical Structure

CAS No. : 759-05-7

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 77 In-stock
Estimated Time of Arrival: December 31
100 mg USD 70 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

3-Methyl-2-oxobutanoic acid is a precursor of pantothenic acid in Escherichia coli.

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

3-Methyl-2-oxobutanoic acid (alpha-Ketoisovaleric acid) is a precursor of pantothenic acid in Escherichia coli[1]. 3-Methyl-2-oxobutanoic acid (alpha-Ketoisovaleric acid) enhances alpha-ketoisocaproic acid and alpha-keto-beta-methyl-n-valeric acid, but diminishes the corresponding amino acids, and causes an early decline of ornithine along with a late augmentation of plasma arginine[2].

In Vivo

3-Methyl-2-oxobutanoic acid (alpha-Ketoisovaleric acid) induces convulsions through GABAergic and glutamatergic mechanisms in rats[3].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 8.6118 mL 43.0589 mL 86.1178 mL
5 mM 1.7224 mL 8.6118 mL 17.2236 mL
10 mM 0.8612 mL 4.3059 mL 8.6118 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

116.12

Formula

C₅H₈O₃

CAS No.

759-05-7

SMILES

CC(C)C(C(O)=O)=O

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Product Name:
3-Methyl-2-oxobutanoic acid
Cat. No.:
HY-W006057
Quantity:

3-Methyl-2-oxobutanoic acid

Cat. No.: HY-W006057