1. Metabolic Enzyme/Protease Anti-infection
  2. Drug Metabolite Antibiotic
  3. 3-Desacetyl Cefotaxime lactone

3-Desacetyl Cefotaxime lactone 

Cat. No.: HY-135394 Purity: 97.02%
COA Handling Instructions

3-Desacetyl Cefotaxime lactone is the active metabolite of Cefotaxime. Cefotaxime sodium salt is a third-generation cephalosporin antibiotic.

For research use only. We do not sell to patients.

3-Desacetyl Cefotaxime lactone Chemical Structure

3-Desacetyl Cefotaxime lactone Chemical Structure

CAS No. : 66340-33-8

Size Price Stock Quantity
5 mg USD 150 In-stock
10 mg USD 230 In-stock
50 mg   Get quote  
100 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

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Description

3-Desacetyl Cefotaxime lactone is the active metabolite of Cefotaxime. Cefotaxime sodium salt is a third-generation cephalosporin antibiotic.

IC50 & Target

β-lactam

 

Molecular Weight

395.41

Formula

C14H13N5O5S2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C1N2[C@@](SCC3=C2C(OC3)=O)([H])[C@@H]1NC(/C(C4=CSC(N)=N4)=N\OC)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (316.13 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5290 mL 12.6451 mL 25.2902 mL
5 mM 0.5058 mL 2.5290 mL 5.0580 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5290 mL 12.6451 mL 25.2902 mL 63.2255 mL
5 mM 0.5058 mL 2.5290 mL 5.0580 mL 12.6451 mL
10 mM 0.2529 mL 1.2645 mL 2.5290 mL 6.3226 mL
15 mM 0.1686 mL 0.8430 mL 1.6860 mL 4.2150 mL
20 mM 0.1265 mL 0.6323 mL 1.2645 mL 3.1613 mL
25 mM 0.1012 mL 0.5058 mL 1.0116 mL 2.5290 mL
30 mM 0.0843 mL 0.4215 mL 0.8430 mL 2.1075 mL
40 mM 0.0632 mL 0.3161 mL 0.6323 mL 1.5806 mL
50 mM 0.0506 mL 0.2529 mL 0.5058 mL 1.2645 mL
60 mM 0.0422 mL 0.2108 mL 0.4215 mL 1.0538 mL
80 mM 0.0316 mL 0.1581 mL 0.3161 mL 0.7903 mL
100 mM 0.0253 mL 0.1265 mL 0.2529 mL 0.6323 mL
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3-Desacetyl Cefotaxime lactone Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
3-Desacetyl Cefotaxime lactone
Cat. No.:
HY-135394
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