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Cat. No.: HY-186293

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3-Lauroylcatechin

3-Lauroylcatechin is a DPPH free radical scavenger. 3-Lauroylcatechin inhibits the activities of mammalian DNA polymerase α and β. 3-Lauroylcatechin can be used in studies related to colon cancer.

For research use only. We do not sell to patients.

CAS No.: 662144-62-9
Formula: C₂₇H₃₆O₇
Molecular Weight:472.57

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

3-Lauroylcatechin Chemical Structure

CAS No.: 662144-62-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
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Biological Activity

Description

All DNA/RNA Synthesis Isoforms :

In Vitro

3-Lauroylcatechin possesses DPPH radical-scavenging activity^[1].
3-Lauroylcatechin (Compound 5) inhibits the activities of DNA polymerase α and DNA polymerase β^[2].
3-Lauroylcatechin (25 μM; 24-72 h) inhibits the growth of colon cancer cell line HCT116 and human umbilical vein endothelial cell line HUVEC, with stronger activity against HUVEC^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay^[2]

Cell Line:

human colon carcinoma HCT116 cells, human umbilical vein endothelial HUVECs
Concentration:

25 μM
Incubation Time:

24 h (HCT116 cells); 72 h (HUVECs)
Result:

Exhibited stronger growth inhibitory potency than shorter acyl-chain catechin derivatives (compounds 2, 3, 4) but weaker potency than longer acyl-chain derivatives (compounds 6, 7, 8).

Chemical Information

CAS No. 662144-62-9
Molecular Weight 472.57
Formula C₂₇H₃₆O₇
SMILES

CCCCCCCCCCCC(O[C@@H]1[C@@H](C2=CC(O)=C(C=C2)O)OC3=CC(O)=CC(O)=C3C1)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Saito K, et al. Synthesis and characterization of lipophilic catechins[J].

[2]. Mizushina Y, et al. Acylated catechin derivatives: inhibitors of DNA polymerase and angiogenesis. Front Biosci (Elite Ed). 2011 Jun 1;3(4):1337-48. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References

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3-Lauroylcatechin

All DNA/RNA Synthesis Isoforms