3'-O-Methylguanosine

Cat. No.: HY-W091784 Purity: 98.66%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

3'-O-Methylguanosine is a methylated nucleoside analogs and a RNA chain terminator. 3'-O-methylguanosine can inhibit early virus-specific RNA synthesis.

For research use only. We do not sell to patients.

3'-O-Methylguanosine Chemical Structure

CAS No. : 10300-27-3

Size	Price	Stock	Quantity
Free Sample (0.1 - 0.5 mg)		Apply Now
5 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 70	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 190	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 270	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

3'-O-Methylguanosine is a methylated nucleoside analogs and a RNA chain terminator. 3'-O-methylguanosine can inhibit early virus-specific RNA synthesis^[1].

IC₅₀ & Target

Human Endogenous Metabolite

Molecular Weight

297.27

Formula

C₁₁H₁₅N₅O₅

CAS No.

10300-27-3

Appearance

Solid

Color

White to off-white

SMILES

O[C@@H]1[C@H](OC)[C@@H](CO)O[C@H]1N2C=NC3=C2NC(N)=NC3=O

Structure Classification

Others

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : 25 mg/mL (84.10 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.3639 mL	16.8197 mL	33.6395 mL
5 mM	0.6728 mL	3.3639 mL	6.7279 mL
10 mM	0.3364 mL	1.6820 mL	3.3639 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.66%

Select Batch:

Data Sheet (273 KB) SDS (393 KB)

COA (250 KB) HNMR (253 KB) RP-HPLC (260 KB) LCMS (94 KB)

Handling Instructions (2659 KB)

References

[1]. B B Goswami, et al. Inhibition of vaccinia virus growth and virus-specific RNA synthesis by 3'-O-methyl adenosine and 3'-O-methyl guanosine. J Virol. 1983 Mar;45(3):1164-7. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.3639 mL	16.8197 mL	33.6395 mL	84.0986 mL
	5 mM	0.6728 mL	3.3639 mL	6.7279 mL	16.8197 mL
	10 mM	0.3364 mL	1.6820 mL	3.3639 mL	8.4099 mL
	15 mM	0.2243 mL	1.1213 mL	2.2426 mL	5.6066 mL
	20 mM	0.1682 mL	0.8410 mL	1.6820 mL	4.2049 mL
	25 mM	0.1346 mL	0.6728 mL	1.3456 mL	3.3639 mL
	30 mM	0.1121 mL	0.5607 mL	1.1213 mL	2.8033 mL
	40 mM	0.0841 mL	0.4205 mL	0.8410 mL	2.1025 mL
	50 mM	0.0673 mL	0.3364 mL	0.6728 mL	1.6820 mL
	60 mM	0.0561 mL	0.2803 mL	0.5607 mL	1.4016 mL
	80 mM	0.0420 mL	0.2102 mL	0.4205 mL	1.0512 mL