1. Anti-infection
  2. Influenza Virus
  3. 2'-Deoxy-2'-fluorocytidine

2'-Deoxy-2'-fluorocytidine 

Cat. No.: HY-W012009 Purity: 99.09%
Handling Instructions

2'-Deoxy-2'-fluorocytidine, an nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. 2′-deoxy-2′-fluorocytidine can act synergistically with T705 to increase the potency of both compounds antiviral effects on CCHFV replication.

For research use only. We do not sell to patients.

2'-Deoxy-2'-fluorocytidine Chemical Structure

2'-Deoxy-2'-fluorocytidine Chemical Structure

CAS No. : 10212-20-1

Size Price Stock Quantity
10 mM * 1 mL in Water USD 55 In-stock
Estimated Time of Arrival: December 31
100 mg USD 50 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

2'-Deoxy-2'-fluorocytidine, an nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. 2′-deoxy-2′-fluorocytidine can act synergistically with T705 to increase the potency of both compounds antiviral effects on CCHFV replication[1].

In Vitro

2'-Deoxy-2'-fluorocytidine has antiviral activities, showing 50% effective concentrations (EC50) of 61 nM and 31 nM against CCHFV and CCHFV/ZsG in Huh7 cells, respectively. And it shows a 50% cytotoxicity concentration (CC50) of >50.0 μM in Huh7 cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

245.21

Formula

C₉H₁₂FN₃O₄

CAS No.

10212-20-1

SMILES
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

H2O : 5 mg/mL (20.39 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.0781 mL 20.3907 mL 40.7814 mL
5 mM 0.8156 mL 4.0781 mL 8.1563 mL
10 mM 0.4078 mL 2.0391 mL 4.0781 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Keywords:

2'-Deoxy-2'-fluorocytidineInfluenza VirusAntiviral,CCHFVCrimean-Congo hemorrhagic fevernucleoside analogInhibitorinhibitorinhibit

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Product Name:
2'-Deoxy-2'-fluorocytidine
Cat. No.:
HY-W012009
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