4-Methyl-5-thiazoleethanol
Based on 1 Customer Validation
4-Methyl-5-thiazoleethanol is a natural sulfur-containing flavor compound with the aroma of beef and nuts. In addition, the composite material prepared by modifying graphene oxide with 4-Methyl-5-thiazoleethanol through a one-step esterification reaction can selectively adsorb copper ions (Cu2+) in aqueous solutions.
For research use only. We do not sell to patients.
- Purity: 99.53%
- CAS No.: 137-00-8
- Formula: C6H9NOS
- Molecular Weight:143.21
-
Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
4-Methyl-5-thiazoleethanol can be found in dog food, and there is a significant positive correlation between it and dog food intake. 4-Methyl-5-thiazoleethanol can increase the first-choice rate and consumption rate of dog food, and it is crucial for enhancing the overall preferred aroma and palatability of dog food[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 137-00-8
-
Appearance Liquid (Density: 1.196 g/cm3)
-
Molecular Weight 143.21
-
Formula C6H9NOS
-
Color Light yellow to yellow
-
SMILES
C1=NC(=C(S1)CCO)C
-
Structure Classification
-
Initial Source
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (698.28 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (17.46 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (17.46 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
-
-
-
-
Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
-
%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
-
%+
-
+%Tween-80 + +
-
%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
-
Data Sheet (291 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.9828 mL | 34.9138 mL | 69.8275 mL | 174.5688 mL |
| 5 mM | 1.3966 mL | 6.9828 mL | 13.9655 mL | 34.9138 mL | |
| 10 mM | 0.6983 mL | 3.4914 mL | 6.9828 mL | 17.4569 mL | |
| 15 mM | 0.4655 mL | 2.3276 mL | 4.6552 mL | 11.6379 mL | |
| 20 mM | 0.3491 mL | 1.7457 mL | 3.4914 mL | 8.7284 mL | |
| 25 mM | 0.2793 mL | 1.3966 mL | 2.7931 mL | 6.9828 mL | |
| 30 mM | 0.2328 mL | 1.1638 mL | 2.3276 mL | 5.8190 mL | |
| 40 mM | 0.1746 mL | 0.8728 mL | 1.7457 mL | 4.3642 mL | |
| 50 mM | 0.1397 mL | 0.6983 mL | 1.3966 mL | 3.4914 mL | |
| 60 mM | 0.1164 mL | 0.5819 mL | 1.1638 mL | 2.9095 mL | |
| 80 mM | 0.0873 mL | 0.4364 mL | 0.8728 mL | 2.1821 mL | |
| 100 mM | 0.0698 mL | 0.3491 mL | 0.6983 mL | 1.7457 mL |
4-Methyl-5-thiazoleethanol Related Classifications
HY-W015695 Related Classifications
Powered by Bioz