4-Desmethyl-2-methyl celecoxib
4-Desmethyl-2-methyl celecoxib (Compound 1g) is an orally active and selective Cyclooxygenase-2 (COX-2) inhibitor with an IC50 value of 0.069 μM. 4-Desmethyl-2-methyl celecoxib shows anti-inflammatory, analgesic, and antipyretic activities. 4-Desmethyl-2-methyl celecoxib can reduces the synthesis of prostaglandins. 4-Desmethyl-2-methyl celecoxib is promising for research of inflammatory diseases and pain-related diseases, such as rheumatoid arthritis and osteoarthritis.
For research use only. We do not sell to patients.
- CAS No.: 170569-99-0
- Formula: C17H14F3N3O2S
- Molecular Weight:381.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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COX-2 0.069 μM (IC50) |
Chemical Information
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CAS No. 170569-99-0
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Molecular Weight 381.37
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Formula C17H14F3N3O2S
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SMILES
O=S(C1=CC=C(N2N=C(C(F)(F)F)C=C2C3=CC=CC=C3C)C=C1)(N)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
4-Desmethyl-2-methyl celecoxib Related Classifications
HY-Z7640 Related Classifications
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