5,6,7,8-Tetrahydro-8-deazahomofolic acid
5,6,7,8-Tetrahydro-8-deazahomofolic acid is a potential thymidylate synthase (TS) inhibitor with inhibitory activity against other folate-related enzymes. 5,6,7,8-Tetrahydro-8-deazahomofolic acid showed mild growth inhibition against enterococci, lactic acid bacteria, and L1210 cells in culture. 5,6,7,8-Tetrahydro-8-deazahomofolic acid also showed weak inhibition against thymidylate synthase, dihydrofolate reductase, glycyl-ribonucleoside aminotransferase, and aminoimidazole-carboxyacyl-ribonucleoside aminotransferase. 5,6,7,8-Tetrahydro-8-deazahomofolic acid showed low substrate activity for thymidylate synthase.
For research use only. We do not sell to patients.
- CAS No.: 111113-75-8
- Formula: C21H26N6O6
- Molecular Weight:458.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
Description
Chemical Information
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CAS No. 111113-75-8
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Molecular Weight 458.47
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Formula C21H26N6O6
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SMILES
O=C1C2=C(NC(N)=N1)CC[C@@H](N2)CCNC3=CC=C(C=C3)C(N[C@H](C(O)=O)CCC(O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
5,6,7,8-Tetrahydro-8-deazahomofolic acid Related Classifications
HY-117247 Related Classifications
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