5-HT1A agonist 1
5-HT1A agonist 1 (Compound Ex.37) is a highly selective 5-HT1a receptor agonist (EC50=0.18 nM). 5-HT1A agonist 1 mimicks serotonin binding to the receptor, promotes postsynaptic membrane hyperpolarization, inhibits neuronal hyperexcitability, and reduces the release of anxiety-related neurotransmitters. 5-HT1A agonist 1 is promising for research of neuropsychiatric diseases.
For research use only. We do not sell to patients.
- CAS No.: 2410053-15-3
- Formula: C22H27N5O2
- Molecular Weight:393.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All 5-HT Receptor Isoforms
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Biological Activity
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5-HT1A Receptor 0.18 nM (EC50) |
Chemical Information
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CAS No. 2410053-15-3
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Molecular Weight 393.48
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Formula C22H27N5O2
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SMILES
CC1=C2C(CCN(CCN3CCC(C4=NOC5=C4C=CC=C5)CC3)C2=O)=NN1C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)