1. Membrane Transporter/Ion Channel
    Neuronal Signaling
    Autophagy
  2. nAChR
    Autophagy
  3. Cisatracurium besylate

Cisatracurium besylate  (Synonyms: 51W89)

Cat. No.: HY-13596 Purity: ≥98.0%
COA Handling Instructions

Cisatracurium besylate (51W89) is a nondepolarizing neuromuscular blocking agent, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission.

For research use only. We do not sell to patients.

Cisatracurium besylate Chemical Structure

Cisatracurium besylate Chemical Structure

CAS No. : 96946-42-8

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Solution
10 mM * 1 mL in Water USD 88 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 88 In-stock
Estimated Time of Arrival: December 31
Solid
25 mg USD 80 In-stock
Estimated Time of Arrival: December 31
50 mg USD 140 In-stock
Estimated Time of Arrival: December 31
100 mg USD 230 In-stock
Estimated Time of Arrival: December 31
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Description

Cisatracurium besylate (51W89) is a nondepolarizing neuromuscular blocking agent, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission.

IC50 & Target

AChR alpha-2[1][2].

In Vitro

Cisatracurium Besylate (51W89) is a neuromuscular-blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs, used adjunctively in anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. It is a bisbenzyltetrahydroisoquinolinium agent with an intermediate duration of action. Cisatracurium Besylate (51W89) is one of the ten isomers of the parent molecule, atracurium. Moreover, cisatracurium represents approximately 15% of the atracurium mixture [1, 2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1243.48

Formula

C65H82N2O18S2

CAS No.
SMILES

O=C(OCCCCCOC(CC[[email protected]+]1(C)[[email protected]](CC2=CC=C(OC)C(OC)=C2)C3=C(C=C(OC)C(OC)=C3)CC1)=O)CC[[email protected]+]4(C)[[email protected]](CC5=CC=C(OC)C(OC)=C5)C6=C(C=C(OC)C(OC)=C6)CC4.O=S(C7=CC=CC=C7)([O-])=O.O=S(C8=CC=CC=C8)([O-])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : ≥ 50 mg/mL (40.21 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8042 mL 4.0210 mL 8.0419 mL
5 mM 0.1608 mL 0.8042 mL 1.6084 mL
10 mM 0.0804 mL 0.4021 mL 0.8042 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (80.42 mM); Clear solution; Need ultrasonic

*All of the co-solvents are available by MCE.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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Product Name:
Cisatracurium besylate
Cat. No.:
HY-13596
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