1. Anti-infection
  2. HCV

Inarigivir soproxil (Synonyms: SB9200)

Cat. No.: HY-109035
Handling Instructions

Inarigivir soproxil is an agonist of innate immunity and shows potent antiviral activity against resistant hepatitis C virus (HCV) variants, with EC50s of 2.2, 1.0 μM for HCV 1a/1b genotype

For research use only. We do not sell to patients.

Inarigivir soproxil Chemical Structure

Inarigivir soproxil Chemical Structure

CAS No. : 942123-43-5

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 851 In-stock
Estimated Time of Arrival: December 31
5 mg USD 550 In-stock
Estimated Time of Arrival: December 31
10 mg USD 850 In-stock
Estimated Time of Arrival: December 31
25 mg USD 1750 In-stock
Estimated Time of Arrival: December 31
50 mg USD 2750 In-stock
Estimated Time of Arrival: December 31
100 mg USD 3950 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Inarigivir soproxil is an agonist of innate immunity and shows potent antiviral activity against resistant hepatitis C virus (HCV) variants, with EC50s of 2.2, 1.0 μM for HCV 1a/1b genotype

IC50 & Target

EC50: 2.2/1.0 μM (HCV 1a/1b)[1].

In Vitro

Inarigivir soproxil (SB 9200) is an oral modulator of innate immunity that is believed to act via the activation of the RIG-I and NOD2 pathways. SB 9200 has broad-spectrum antiviral activity against RNA viruses including hepatitis C virus (HCV), norovirus, respiratory syncytial virus and influenza and has demonstrated activity against hepatitis B virus (HBV). Inarigivir soproxil is shown to inhibit HCV replication and the range of inhibition is comparable between genotypes 1a and 1b. Inarigivir soproxil demonstrates pan-genotypic antiviral activity against HCV. Inarigivir soproxil is active against DAA-resistant HCV variants[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4212 mL 7.1061 mL 14.2122 mL
5 mM 0.2842 mL 1.4212 mL 2.8424 mL
10 mM 0.1421 mL 0.7106 mL 1.4212 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

703.62

Formula

C₂₅H₃₄N₇O₁₃PS

CAS No.

942123-43-5

SMILES

CO[[email protected]]1[[email protected]](N(C=CC2=O)C(N2)=O)O[[email protected]](CO)[[email protected]]1OP(OC[[email protected]]3O[[email protected]@H](N4C5=NC=NC(N)=C5N=C4)C[[email protected]@H]3O)(SCOC(OC(C)C)=O)=O

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Product Name:
Inarigivir soproxil
Cat. No.:
HY-109035
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Inarigivir soproxil

Cat. No.: HY-109035