Angiotensin Receptor
Angiotensin receptors are a class of G protein-coupled receptors with angiotensin II as their ligands. They are important in the renin-angiotensin system: they are responsible for the signal transduction of the vasoconstricting stimulus of the main effector hormone, angiotensin II. The AT1 and AT2 receptors have a similar affinity for angiotensin II, which is their main ligand. The AT1 receptor is the best elucidated angiotensin receptor. AT2 receptors are more plentiful in the fetus and neonate. Other poorly characterized subtypes include the AT3 and AT4 receptors.
Angiotensin Receptor Isoform Specific Products
All Product Categories
-
Angiotensin Receptor Inhibitors
(34)
View all products
-
Angiotensin Receptor Agonists
(24)
View all products
-
Angiotensin Receptor Antagonists
(164)
View all products
-
Angiotensin Receptor Activators
(33)
View all products
-
Angiotensin Receptor Modulators
(3)
View all products
-
Angiotensin Receptor Chemicals
(2)
View all products
-
Angiotensin Receptor Ligands
(2)
View all products
-
Angiotensin Receptor Related Products (300)
Related Products (300)
-
Antibodies (7)
-
Angiotensin Receptor Isoform Comparison
-
Elisartan
0 ImagesCat. No.: HY-19214CAS No.: 149968-26-3Synonyms: HN 65021Elisartan is an orally active non-peptide pro-agent of angiotensin II AT1 receptor antagonist HN-12206, and shows anti-hypertension activities.
-
CGP48369
0 ImagesCat. No.: HY-101706CAS No.: 135689-23-5CGP48369 is a nonpeptidic angiotensin II receptor antagonist, used for anti-hypertensive research.
-
L-159282
0 ImagesCat. No.: HY-19191CAS No.: 157263-00-8Synonyms: MK 996L-159282 is a highly potent, orally active, nonpeptide angiotensin II receptor antagonist, with anti-hypertensive activity.
-
L162389
0 ImagesL162389 is a potent antagonist of angiotensin AT1 receptor with Ki of 28 nM.
-
A-81282
0 ImagesCat. No.: HY-101823ACAS No.: 141872-46-0Synonyms: Abbott 81282A-81282 (Abbott 81282) is an antagonist of angiotensin II's AT1 receptor, with a pA2 value of 9.64 at the AT1 receptor in rabbit aorta. A-81282 also demonstrates significant inhibitory action on the binding of [125i]_Sar1_lle8_Angiotensin_ll to rat liver membranes, with a pKI value of 8.505. A-81282 has antihypertensive activity and can effectively lower blood pressure in renal artery-ligated rats.
-
AT2 receptor ligand-1
0 ImagesCat. No.: HY-162125CAS No.: 3027141-86-9AT2 receptor ligand-1(compound 14) is a potent angiotensin AT2 receptor ligand with the Ki 4.9 nM. AT2 receptor ligand-1 shows high stability in microsomes of the sulfonamide ligands.
-
PD 123319 ditrifluoroacetate (Standard)
0 ImagesCat. No.: HY-10259ARCAS No.: 136676-91-0PD 123319 ditrifluoroacetate (Standard) is the analytical standard of PD 123319 ditrifluoroacetate (HY-10259A). This product is intended for research and analytical applications. PD 123319 ditrifluoroacetate is a potent, selective AT2 angiotensin II receptor antagonist with IC50 of 34 nM.
-
Nepitrin (Standard)
0 ImagesNepitrin (Standard) (Nepetin-7-glucoside (Standard)) is the analytical standard of Nepitrin (HY-N5010). This product is intended for research and analytical applications. Nepitrin (Nepetin-7-glucoside) is an orally active bradykinin and angiotensin antagonist isolated from Scrophularia striata. Nepitrin antagonizes the spasmogenic effects of Bradykinin and Angiotensin, thereby inhibiting inflammatory mediator pathways. Nepitrin is applicable to arthritis-related research.
-
2-(Aminomethyl)-4-methylphenol hydrochloride
0 ImagesSynonyms: 5-Methyl-2-HOBA hydrochloride2-(Aminomethyl)-4-methylphenol (5-methyl-2-HOBA) hydrochloride is an isoketal scavenger that attenuates the hypertensive response to angiotensin II.
-
ZD 7155hydrochloride (Standard)
0 ImagesCat. No.: HY-102093RCAS No.: 146709-78-6ZD 7155(hydrochloride) (Standard) is the analytical standard of ZD 7155(hydrochloride). This product is intended for research and analytical applications. ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist.
-
KR-31080
0 ImagesCat. No.: HY-167853CAS No.: 174800-22-7Synonyms: SK-1080KR-31080 is an derivative of imidazo [4,5-b] pyridine. KR-31080 inhibits angiotensin II receptor. KR-31080 inhibits the NO production in LPS-stimulated BV-2 cells at a concentration of 2 μm with inhibition of 8.3%.
-
Olmesartan lactone impurity (Standard)
0 ImagesCat. No.: HY-131276RCAS No.: 849206-43-5Olmesartan lactone impurity (Standard) is the analytical standard of Olmesartan lactone impurity. This product is intended for research and analytical applications. Olmesartan lactone impurity is a cyclic ester impurity of Olmesartan. Olmesartan is an angiotensin II receptor (AT1R) antagonist and has the potential for high blood pressure study.
-
Olmesartan impurity
0 ImagesCat. No.: HY-133775CAS No.: 154709-18-9Olmesartan impurity is an Olmesartan impurity. Olmesartan (RNH-6270) is an angiotensin II receptor (AT1R) antagonist has the potential for high blood pressure study.
-
GA 0113
0 ImagesCat. No.: HY-167886CAS No.: 200639-61-8
-
Azilsartan medoxomil (Standard)
0 ImagesSynonyms: TAK-491 (Standard)Azilsartan medoxomil (Standard) is the analytical standard of Azilsartan medoxomil (HY-14736). This product is intended for research and analytical applications. Azilsartan medoxomil (TAK 491), a prodrug form of Azilsartan (HY-14914), is an orally active angiotensin II receptor type 1 antagonist. Azilsartan medoxomil can be used for the study of essential hypertension.
-
RG 13647
0 ImagesCat. No.: HY-120238CAS No.: 145543-03-9RG 13647 is an AT2-selective ligand. RG 13647 is an analog of PD 123177 (HY-121767). RG 13647 shows weak activity in competing for [125I]angiotensin II binding with an IC50 value of 100 μM. RG 13647 can be used for research of cardiovascular disease.
-
Perindopril arginine
0 ImagesPerindopril arginine is an angiotensin-converting enzyme inhibitor with hypotensive activity. Perindopril arginine is used to inhibit hypertension to lower blood pressure. Perindopril arginine, when used in combination with indapamide and amlodipine, can effectively lower blood pressure and provide better target organ protection.
-
L162441
0 ImagesCat. No.: HY-U00245CAS No.: 154512-46-6L162441 is an Angiotensin type 1 receptor antagonist.
-
LY285434
0 ImagesCat. No.: HY-U00202CAS No.: 159748-08-0LY285434 is a suitable angiotensin II receptor antagonist.
-
A81988
0 ImagesCat. No.: HY-U00188CAS No.: 141887-34-5Synonyms: Abbott81988A81988 is a potent, competitive, non-peptidic antagonist of angiotensin AT1 receptors.
