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Cat. No.: HY-167886

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GA 0113

GA 0113 is a potent and orally active angiotensin II (Ang II) AT1-receptor antagonist. GA 0113 inhibits the Ang II (HY-13948)-induced pressor response with ID₅₀ of 0.032 mg/kg and dose-dependently increases plasma renin activity for 48 h.

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CAS No.: 200639-61-8
Formule: C₂₇H₂₄F₃N₅O₂S
Masse moléculaire:539.57

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

GA 0113 Chemical Structure

CAS No.: 200639-61-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

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Chemical Information

CAS No. 200639-61-8
Masse moléculaire 539.57
Formule C₂₇H₂₄F₃N₅O₂S
SMILES

O=S(NC1=C(C2=NC3=C(C=C2)C=C(CN4C5=NC(C)=CC(C)=C5N=C4CC)C=C3)C=CC=C1)(C(F)(F)F)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Ebisu H, et al. Pharmacologic profiles of GA0113, a novel quinoline derivative angiotensin II AT1-receptor antagonist. J Cardiovasc Pharmacol. 1999 Oct;34(4):526-32. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Activité biologique
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Chemical Information
Pureté et documentation
Références

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GA 0113

Voir tous les produits spécifiques à Isoform Angiotensin Receptor