Calcium Channel
Ca2+ channels; Ca channels
Calcium channel is an ion channel which displays selective permeability to calcium ions. It is sometimes synonymous as voltage-dependent calcium channel, although there are also ligand-gated calcium channels. Voltage-gated calcium (CaV) channels catalyse rapid, highly selective influx of Ca2+ into cells despite a 70-fold higher extracellular concentration of Na+. Some calcium channel blockers have the added benefit of slowing your heart rate, which can further reduce blood pressure, relieve chest pain (angina) and control an irregular heartbeat.
Calcium Channel Isoform Specific Products
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Calcium Channel Inhibitors
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Calcium Channel Agonists
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Calcium Channel Antagonists
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Calcium Channel Activators
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Calcium Channel Modulators
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Calcium Channel Chemical
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Calcium Channel Inducers
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Calcium Channel Controls
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Calcium Channel Ligands
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Calcium Channel Related Products (1237)
Related Products (1237)
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Antibodies (29)
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Related Compound Screening Libraries (1)
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Calcium Channel Isoform Comparison
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Amlodipine hydrochloride
0 ImagesCat. No.: HY-B0317FCAS No.: 246852-07-3Amlodipine hydrochloride is a biologically active drug used to lower blood pressure and prevent chest pain. Amlodipine hydrochloride has shown synergistic effects with antimicrobial drugs in in vitro studies, especially against carbene peptide-resistant Acinetobacter baumannii. Amlodipine hydrochloride can be used in combination with other antibiotics to enhance the inhibitory effect against resistant bacteria. The use of amlodipine hydrochloride helps reduce the dosage requirements of the drug, reduce toxic effects, and delay the emergence of drug resistance.
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Lomerizine dihydrochloride (Standard)
0 ImagesSynonyms: KB-2796 (Standard)Lomerizine dihydrochloride (Standard) is the analytical standard of Lomerizine dihydrochloride. This product is intended for research and analytical applications. Lomerizine dihydrochloride is an antagonist of L- and T-type voltagegated calcium channels.
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Lomerizine-d4
0 ImagesCat. No.: HY-B0768SLomerizine-d4 is the deuterium labeled Lomerizine (HY-B0768). Lomerizine is an antagonist of L- and T-type voltagegated calcium channels.
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DHP-218
0 ImagesCat. No.: HY-106766CAS No.: 102097-78-9DHP-218 is a vasodilatory calcium antagonist with pronounced and long-lasting antihypertensive effects .
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Amlodipine (Standard)
0 ImagesAmlodipine (Standard) is the analytical standard of Amlodipine. This product is intended for research and analytical applications. Amlodipine, an antianginal agent and an orally active dihydropyridine calcium channel blocker, works by blocking the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium. Amlodipine can be used for the research of high blood pressure and cancer.
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Falipamil
0 ImagesCat. No.: HY-106682CAS No.: 77862-92-1Synonyms: AQ-A 39Falipamil (AQ-A 39), a calcium channel blocker, is a bradycardic agent. The bradycardic effect results from a reduction in the diastolic depolarization rate and a prolongation of the action potential duration.
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Clevidipine (Standard)
0 ImagesClevidipine (Standard) is the analytical standard of Clevidipine. This product is intended for research and analytical applications. Clevidipine is a short-acting dihydropyridine calcium channel antagonist (IC50= 7.1 nM, V(H) = -40 mV ).
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Cav 3.1 blocker 1
0 ImagesCat. No.: HY-156889CAS No.: 2158201-04-6Cav 3.1 blocker 1 (compound 12) is a T-type calcium channel blocker with an IC50value of 160 nM for Cav3.1. Cav 3.1 blocker 1 weakly inhibits Cav 3.2 (IC50 of 5000 nM), and shows no inhibition on Cav 3.3 and Cav 1.2 (IC50 of >10000 nM).
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Drotaverine hydrochloride (Standard)
0 ImagesDrotaverine (hydrochloride) (Standard) is the analytical standard of Drotaverine (hydrochloride). This product is intended for research and analytical applications. Drotaverine hydrochloride is a type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor and an L-type voltage-dependent calcium channel (L-VDCC) blocker, blocks the degradation of 3',5'-cyclic adenosine monophosphate. Drotaverine (hydrochloride) exhibits in vivo antispasmodic efficacy without anticholinergic effects.
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SIM-6080
0 ImagesCat. No.: HY-19083CAS No.: 118790-68-4SIM-6080 is a calcium antagonist and inhibits the proliferation of rat aortic myocytes and reduces aortic atherosclerosis in rabbits.
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TTA-Q6 (Standard)
0 ImagesCat. No.: HY-10388RCAS No.: 910484-28-5TTA-Q6 (Standard) is the analytical standard of TTA-Q6 (HY-10388). This product is intended for research and analytical applications. TTA-Q6 is a selective T-type Ca2+ channel antagonist, which can be used in the research of neurological disease.
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Flordipine
0 ImagesCat. No.: HY-121019CAS No.: 77590-96-6Floripine is an orally active calcium antagonist with anti hypertensive activity.
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Riodipine
0 ImagesCat. No.: HY-118492CAS No.: 71653-63-9Synonyms: Foridon; PP-1466Riodipine (PP-1466) is a vasodilator. Riodipine can be used for the research of antihypertensive.
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Fostedil
0 ImagesCat. No.: HY-106239CAS No.: 75889-62-2Synonyms: KB 944Fostedil (KB 944) is a calcium antagonist that can be used in the research of heart diseases such as angina pectoris.
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Amlodipine-1,1,2,2-d4 maleate
0 ImagesAmlodipine-1,1,2,2-d4 (maleate) is the deuterium labeled Amlodipine. Amlodipine, an antianginal agent and an orally active dihydropyridine calcium channel blocker, works by blocking the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium. Amlodipine can be used for the research of high blood pressure and cancer.
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TTA-A2 (Standard)
0 ImagesCat. No.: HY-111828RCAS No.: 953778-63-7TTA-A2 (Standard) is the analytical standard of TTA-A2 (HY-111828). This product is intended for research and analytical applications. TTA-A2 is a potent, selective and orally active t-type voltage gated calcium channel antagonist with reduced pregnane X receptor (PXR) activation. TTA-A2 is equally potent against the Cav3.1 (a1G) and Cav3.2 (a1H) channels with IC50 values of 89 nM and 92 nM, respectively, at -80 and -100 mV holding potentials. TTA-A2 can be used for the research of a variety of human neurological diseases, including sleep disorders and epilepsy.
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EO-122
0 ImagesCat. No.: HY-107186CAS No.: 23581-62-6EO-122 is a potent antagonist of calcium channel and sodium channel potentially for the research of arrhythmia.
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Diltiazem-d5 hydrochloride
0 ImagesCat. No.: HY-14656S3CAS No.: 2012598-70-6Synonyms: CRD-401-d5 hydrochlorideDiltiazem-d5 (CRD-401-d5) hydrochloride is deuterium-labeled Diltiazem (hydrochloride) (HY-14656).
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AJG049 free base
0 ImagesCat. No.: HY-167203CAS No.: 195991-49-2AJG049 free base is a calcium channel (Ca2+ channel) antagonist. AJG049 free base regulates vascular relaxation, reduces cardiac load, and improves cardiac perfusion by binding to the binding site of L-type calcium channels, specifically Diltiazem (HY-B0632). AJG049 free base can be used in cardiovascular disease research.
