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Cat. No.: HY-118492

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Riodipine

Name: Riodipine
Brand: MedChemExpress
SKU: HY-118492
Availability: PreOrder

(Synonyms: Foridon; PP-1466)

Riodipine (PP-1466) is a vasodilator. Riodipine can be used for the research of antihypertensive.

For research use only. We do not sell to patients.

CAS No.: 71653-63-9
Formula: C₁₈H₁₉F₂NO₅
Molecular Weight:367.34

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Riodipine Chemical Structure

CAS No.: 71653-63-9

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
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Biological Activity

Description

Riodipine (PP-1466) is a vasodilator. Riodipine can be used for the research of antihypertensive^[1].

IC₅₀ & Target

Riodipine;Foridon;PP 1466;PP1466;PP-1466

All Calcium Channel Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	EC₅₀	1.6 μM Compound: Riodipine	Activation of human PXR expressed in human HepG2 (DPX-2) cells assessed as induction of CYP3A4 after 24 hrs by luminescent analysis Activation of human PXR expressed in human HepG2 (DPX-2) cells assessed as induction of CYP3A4 after 24 hrs by luminescent analysis	[PMID: 20966043]
HepG2	EC₅₀	1.8 μM Compound: Riodipine	Activation of rat PXR expressed in human HepG2 cells after 24 hrs by luciferase reporter gene based luminescent analysis Activation of rat PXR expressed in human HepG2 cells after 24 hrs by luciferase reporter gene based luminescent analysis	[PMID: 20966043]
HepG2	EC₅₀	4 μM Compound: Riodipine	Activation of human PXR expressed in human HepG2 (DPX-2) cells after 24 hrs by luciferase reporter gene based luminescent analysis Activation of human PXR expressed in human HepG2 (DPX-2) cells after 24 hrs by luciferase reporter gene based luminescent analysis	[PMID: 20966043]

Chemical Information

CAS No. 71653-63-9
Molecular Weight 367.34
Formula C₁₈H₁₉F₂NO₅
SMILES

O=C(OC)C1=C(NC(C)=C(C1C2=CC=CC=C2OC(F)F)C(OC)=O)C
Synonyms

Foridon; PP-1466
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Inoue, Y. et al. Absorption, distribution, metabolism and excretion of 2,6-dimethyl-3,5-dimethoxycarbonyl-4-(o-difluoromethoxyphenyl)-1,4-dihydropyridine (PP-1466) in rats. Arzneimittel-Forschung. Volume: 35. Issue: 5. Pages: 813-18. Journal; Article. 1985.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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Riodipine

All Calcium Channel Isoforms