Cav 3.1 blocker 1
Cav 3.1 blocker 1 (compound 12) is a T-type calcium channel blocker with an IC50value of 160 nM for Cav3.1. Cav 3.1 blocker 1 weakly inhibits Cav 3.2 (IC50 of 5000 nM), and shows no inhibition on Cav 3.3 and Cav 1.2 (IC50 of >10000 nM).
For research use only. We do not sell to patients.
- CAS No.: 2158201-04-6
- Formula: C26H19F6N3O2
- Molecular Weight:519.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Calcium Channel Isoforms
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Biological Activity
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CaV3.1 160 nM (IC50) |
Cav3.2 5000 nM (IC50) |
CaV3.3 >10000 nM (IC50) |
CaV 1.2 >10000 nM (IC50) |
Chemical Information
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CAS No. 2158201-04-6
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Molecular Weight 519.44
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Formula C26H19F6N3O2
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SMILES
O=C(C1=NN(C(C2=CC=CC=C2)=C1C(F)F)C3=CC=C(C=C3)F)NCC4=C(OCC(F)(F)F)C=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)