2. Signaling Pathways
  3. Apoptosis
  4. IAP
  5. cIAP-1 Isoform
  6. cIAP-1 Antagonist

cIAP-1 Antagonist

cIAP-1 Antagonists (6):

Cat. No. Product Name Effect Purity
  • HY-12600
    AZD5582
    		Antagonist 98.11%
    AZD5582 is an antagonist of the inhibitor of apoptosis proteins (IAPs), which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively.
  • HY-15989
    SM-164
    		Antagonist 99.65%
    SM-164 is a cell-permeable Smac mimetic compound.
  • HY-15454
    Xevinapant
    		Antagonist 99.94%
    Xevinapant (AT-406) is a potent and orally bioavailable Smac mimetic and an antagonist of IAPs, and it binds to XIAP, cIAP1, and cIAP2 proteins with Ki of 66.4, 1.9, and 5.1 nM, respectively.
  • HY-15989A
    SM-164 Hydrochloride
    		Antagonist 99.0%
    SM-164 Hydrochloride is a cell-permeable Smac mimetic compound.
  • HY-13208
    Xevinapant hydrochloride
    		Antagonist 98.80%
    Xevinapant (AT-406) hydrochloride is a potent and orally bioavailable Smac mimetic and an antagonist of the inhibitor of apoptosis proteins (IAPs).
  • HY-110346
    AZD5582 dihydrochloride
    		Antagonist 98.67%
    AZD5582 dihydrochloride is an antagonist of the inhibitor of apoptosis proteins (IAPs), which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively.