Integrin
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Integrin Ligands
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Integrin Related Products (383)
Related Products (383)
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Necrosulfonamide-d4
0 ImagesNecrosulfonamide-d4 is the deuterium labeled Necrosulfonamide (HY-100573). Necrosulfonamide is a MLKL and Gasdermin D (GSDMD) inhibitor, capable of separately inhibiting necroptosis and pyroptosis of cells. Necrosulfonamide does not affect the activation of upstream signals, but specifically inhibits the downstream executor oligomerization step. Necrosulfonamide reduces the expression of the key kinases NLRP3 and caspase-1 involved in necroptosis and pyroptosis, activate the Nrf2 pathway and the downstream antioxidant enzymes, and also downregulates a variety of inflammatory factors. Necrosulfonamide plays significant roles in various diseases such as neurodegenerative diseases (such as Parkinson’s disease), tissue damage and ischemia-reperfusion injury, inflammatory bowel disease, osteoarthritis and fracture repair, and hair loss by regulating two important programmed necrosis pathways.
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Anti-Mouse CD103 Antibody (M290)
0 ImagesCat. No.: HY-P990295Purity: 98.93%Anti-Mouse CD103 Antibody (M290) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse CD103. Anti-Mouse CD103 Antibody (M290) can neutralize CD103. Anti-Mouse CD103 Antibody (M290) can be used for the researches of cancer, inflammation, immunology and metabolic disease, such as B16.gp33 tumor, colitis and diabetes.
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13-Hydroxylupanine
0 ImagesCat. No.: HY-119926CAS No.: 15358-48-2Synonyms: Hydroxylupanine13-Hydroxylupanine (Hydroxylupanine) is the typical alkaloid profile of sweet lupins.13-Hydroxylupanine blocks ganglionic transmission, decreases cardiac contractility and contracts uterine smooth muscle.
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Egaptivon pegol sodium
0 ImagesCat. No.: HY-147079ASynonyms: ARC 1779 sodiumEgaptivon pegol sodium is an aptamer, which blocks binding of the von Willebrand Factor (VWF) to platelet GPIb receptors. Egaptivon pegol sodium has anti-thrombotic efficacy.
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K34c hydrochloride
0 ImagesCat. No.: HY-150124ACAS No.: 2986315-25-5
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AFP464 dihydrochloride
0 ImagesCat. No.: HY-16031BPurity: 99.45%Synonyms: NSC710464 dihydrochlorideAFP464 (NSC710464) dihydrochloride is a prodrug of Aminoflavone (HY-132974) and an agonist of the aryl hydrocarbon receptor (AhR). AFP464 dihydrochloride downregulates the expression of α6-integrin (α6-integrin), inhibits breast tumor growth, reduces the population of tumor-initiating cells, disrupts mammosphere structure, induces the formation of mucin lake clusters, triggers DNA damage, and exerts antiproliferative activity. AFP464 dihydrochloride is rapidly converted to Aminoflavone by nonspecific esterases in plasma and cell culture media. AFP464 dihydrochloride is applicable to research related to breast cancer.
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Egaptivon pegol
0 ImagesCat. No.: HY-147079CAS No.: 934868-74-3Synonyms: ARC 1779Egaptivon pegol (ARC1779) is an aptamer, which blocks binding of the von Willebrand Factor (VWF) to platelet GPIb receptors. Egaptivon pegol has anti-thrombotic efficacy.
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Cyclo(Gly-Arg-Gly-Asp-Ser-Pro)
0 ImagesSynonyms: c(GRGDSP)
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Anti-Mouse CD11a Antibody (FD441.8)
0 ImagesCat. No.: HY-P99120Anti-Mouse CD11a Antibody (FD441.8) is an anti-mouse CD11a IgG2b antibody inhibitor derived from the host Rat. Anti-Mouse CD11a Antibody (FD441.8) can neutralize CD11a also known as LFA-1α (lymphocyte function-associated antigen 1 alpha). Anti-Mouse CD11a Antibody (FD441.8) can be used for the researches of inflammation, immunology and cancer, such as transplant and leukemia.
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Anti-Mouse CD29 Antibody (KMI6)
0 ImagesCat. No.: HY-P990278Purity: 98.67%
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c(phg-isoDGR-(NMe)k)
0 ImagesCat. No.: HY-111413CAS No.: 1844830-65-4c(phg-isoDGR-(NMe)k) is a selective and potent α5β1-integrin ligand with an IC50 of 2.9 nM.
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Zalunfiban
0 ImagesCat. No.: HY-119350CAS No.: 1448313-27-6Synonyms: RUC-4Zalunfiban (RUC-4) is a potent, selective platelet αIIbβ3 antagonist (IC50=45 nM). Zalunfiban can be used for the research of myocardial infarction (MI).
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Fuzapladib sodium
0 ImagesSynonyms: IS-741 sodiumFuzapladib (IS-741) sodium, an orally active leukocyte-function-associated antigen type 1 (LFA-1) activation inhibitor, is a leukocyte adhesion molecule. Fuzapladib sodium is also a phospholipase A2 (PLA2) inhibitor. Fuzapladib sodium exerts anti-inflammatory effects by inhibiting leukocyte migration into the inflammatory site.
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12(S)-HETrE
0 Images12(S)-HETrE is a fatty acid metabolite that inhibits platelet aggregation. 12(S)-HETrE can be used in thrombosis-related research.
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Sigvotatug (Biotinylated)
0 ImagesCat. No.: HY-P990764BSigvotatug (Biotinylated) is a biotinylated derivative of Sigvotatug (HY-P990764). Sigvotatug (Biotinylated) is a humanized IgG1 κ monoclonal antibody inhibitor against ITGB6. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
