K34c hydrochloride
Based on 1 Customer Validation
K34c hydrochloride is a potent and selective α5β1 integrin antagonist. By inhibiting α5β1 integrin, K34c hydrochloride reduces chemotherapy-induced premature senescence and promotes apoptosis. K34c hydrochloride can be used in glioblastoma research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2986315-25-5
- 分子式: C26H30ClN3O4
- 分子量:483.99
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保管条件:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
体外実験
K34c (20 μM; 24 or 48 h) significantly induces U87MG cells apoptosis in combination with 1 μM Ellipticine (HY-15753)[1].
K34c (20 μM; 48 h) significantly decreases Temozolomide (HY-17364)-induced senescence in cells transfected with control non targeting siRNA without affecting significantly the residual senescence of cells transfected with siRNA specific for p53[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2986315-25-5
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性状 Solid
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分子量 483.99
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分子式 C26H30ClN3O4
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SMILES
O=C(O)[C@H](CC1=CC=C(OCCCNC2=NC=CC=C2)C=C1)NC(C3=C(C)C=CC=C3C)=O.Cl
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
体外:
DMSO : 125 mg/mL (258.27 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (270 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0662 mL | 10.3308 mL | 20.6616 mL | 51.6540 mL |
| 5 mM | 0.4132 mL | 2.0662 mL | 4.1323 mL | 10.3308 mL | |
| 10 mM | 0.2066 mL | 1.0331 mL | 2.0662 mL | 5.1654 mL | |
| 15 mM | 0.1377 mL | 0.6887 mL | 1.3774 mL | 3.4436 mL | |
| 20 mM | 0.1033 mL | 0.5165 mL | 1.0331 mL | 2.5827 mL | |
| 25 mM | 0.0826 mL | 0.4132 mL | 0.8265 mL | 2.0662 mL | |
| 30 mM | 0.0689 mL | 0.3444 mL | 0.6887 mL | 1.7218 mL | |
| 40 mM | 0.0517 mL | 0.2583 mL | 0.5165 mL | 1.2913 mL | |
| 50 mM | 0.0413 mL | 0.2066 mL | 0.4132 mL | 1.0331 mL | |
| 60 mM | 0.0344 mL | 0.1722 mL | 0.3444 mL | 0.8609 mL | |
| 80 mM | 0.0258 mL | 0.1291 mL | 0.2583 mL | 0.6457 mL | |
| 100 mM | 0.0207 mL | 0.1033 mL | 0.2066 mL | 0.5165 mL |
K34c hydrochloride 関連分類
HY-150124A 関連分類
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