K34c hydrochloride
Based on 1 Customer Validation
K34c hydrochloride is a potent and selective α5β1 integrin antagonist. By inhibiting α5β1 integrin, K34c hydrochloride reduces chemotherapy-induced premature senescence and promotes apoptosis. K34c hydrochloride can be used in glioblastoma research.
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- CAS No.: 2986315-25-5
- Formule: C26H30ClN3O4
- Masse moléculaire:483.99
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Stockage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
K34c (20 μM; 24 or 48 h) significantly induces U87MG cells apoptosis in combination with 1 μM Ellipticine (HY-15753)[1].
K34c (20 μM; 48 h) significantly decreases Temozolomide (HY-17364)-induced senescence in cells transfected with control non targeting siRNA without affecting significantly the residual senescence of cells transfected with siRNA specific for p53[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2986315-25-5
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Appearance Solid
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Masse moléculaire 483.99
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Formule C26H30ClN3O4
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SMILES
O=C(O)[C@H](CC1=CC=C(OCCCNC2=NC=CC=C2)C=C1)NC(C3=C(C)C=CC=C3C)=O.Cl
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvant et solubilité
DMSO : 125 mg/mL (258.27 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (270 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0662 mL | 10.3308 mL | 20.6616 mL | 51.6540 mL |
| 5 mM | 0.4132 mL | 2.0662 mL | 4.1323 mL | 10.3308 mL | |
| 10 mM | 0.2066 mL | 1.0331 mL | 2.0662 mL | 5.1654 mL | |
| 15 mM | 0.1377 mL | 0.6887 mL | 1.3774 mL | 3.4436 mL | |
| 20 mM | 0.1033 mL | 0.5165 mL | 1.0331 mL | 2.5827 mL | |
| 25 mM | 0.0826 mL | 0.4132 mL | 0.8265 mL | 2.0662 mL | |
| 30 mM | 0.0689 mL | 0.3444 mL | 0.6887 mL | 1.7218 mL | |
| 40 mM | 0.0517 mL | 0.2583 mL | 0.5165 mL | 1.2913 mL | |
| 50 mM | 0.0413 mL | 0.2066 mL | 0.4132 mL | 1.0331 mL | |
| 60 mM | 0.0344 mL | 0.1722 mL | 0.3444 mL | 0.8609 mL | |
| 80 mM | 0.0258 mL | 0.1291 mL | 0.2583 mL | 0.6457 mL | |
| 100 mM | 0.0207 mL | 0.1033 mL | 0.2066 mL | 0.5165 mL |
K34c hydrochloride Related Classifications
HY-150124A Related Classifications
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