2. Signaling Pathways
  3. Cytoskeleton
  4. Integrin
  5. Integrin Isoform
  6. Integrin Ligand

Integrin Ligand

Integrin Ligands (16):

Cat. No. Product Name Effect Purity
  • HY-P1897A
    Fibronectin sctive fragment control acetate
    		Ligand 99.19%
    Fibronectin active fragment control acetate is an active peptide fragment of fibronectin. Fibronectin is a glycoprotein interacting with integrins. Fibronectin active fragment control acetate can be used as a control for Gly-Arg-Gly-Asp-Ser (HY-P0295).
  • HY-P990764
    Sigvotatug
    		Ligand 99.67%
    Sigvotatug (SGN-B6A antibody) is a human IgG1 κ monoclonal antibody against ITGB6. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001). Sigvotatug can be used as an ADC antibody to synthesize ADC Sigvotatug vedotin (HY-164957).
  • HY-P5098
    E(c(RGDfK))2
    		Ligand 99.82%
    E (c (RGDfK)) 2 is a αvβ3 integrin ligand and tumor-targeting agent. E (c (RGDfK)) 2 binds to αvβ3 integrin, mediates receptor-mediated endocytosis of conjugated payloads, and inhibits integrin-dependent cell adhesion to fibrinogen. E (c (RGDfK)) 2 inhibits the proliferation of cancer cells and endothelial cells. E (c (RGDfK)) 2 preferentially accumulates in orthotopic mouse breast tumors and human ovarian cancer xenograft tumors. E (c (RGDfK)) 2 can be used in research related to glioblastoma, lung cancer, breast adenocarcinoma and ovarian cancer.
  • HY-P990764B
    Sigvotatug (Biotinylated)
    		Ligand ≥99.0%
    Sigvotatug (Biotinylated) is a biotinylated derivative of Sigvotatug (HY-P990764). Sigvotatug (Biotinylated) is a humanized IgG1 κ monoclonal antibody inhibitor against ITGB6. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
  • HY-177580
    GP1 precursor
    		Ligand
    GP1 precursor has high affinity to GPIIb/IIIa receptors of activated platelets. GP1 precursor can be radiolabeled with [18F] and used as a PET Tracer for visualizing active platelet aggregation at the molecular level. GP1 precursor can be used for the detection of Thrombi.
  • HY-P11708
    Relitegatide
    		Ligand
    Relitegatide is a cyclic peptide with selectivity for the αvβ6 integrin. Relitegatide can be used for the synthesis of Relitegatide brexetan (HY-P11276).
  • HY-176300
    RGD-DA6
    		Ligand
    RGD-DA6 is an αvβ3-targeted ligand. RGD-DA6 consists of RGDfK (an integrin αvβ3-targeted RGD peptide), DOTADG, d-Glu, Lys, AMBA, and IPBA. RGD-DA6 can be radiolabeled as an αvβ3-targeted radioligand and used for high-contrast tumor imaging and enhanced anticancer efficacy.
  • HY-185469
    Tris-ανβ6 integrin ligand-3
    		Ligand
    Tris-ανβ6 integrin ligand-3 (the ligand part of Compound 203) is a Tris-ανβ6 integrin ligand.
  • HY-P3530
    G-{d-Arg}-GDSP
    		Ligand
    G-{d-Arg}-GDSP is an RGD peptide analogue that binds to the adhesion receptor of integrins and inhibits cellular fibronectin attachment as well as osteoclast resorption.
  • HY-185468
    Tris-ανβ6 integrin ligand-2
    		Ligand
    Tris-ανβ6 integrin ligand-2 (the ligand part of Compound 151) is a Tris-ανβ6 integrin ligand.
  • HY-P2153
    Maraciclatide
    		Ligand
    Maraciclatide is a synthetic molecule that binds with high affinity to αvβ3 and αvβ5 integrins via the RGD peptide. Maraciclatide can be used to detect bone metastasis, breast tumors, vascular disease and rheumatoid arthritis in animal models. Maraciclatide can be studied in research on angiogenesis and inflammation.
  • HY-185466
    ανβ6 Integrin ligand-2
    		Ligand
    ανβ6 Integrin ligand-2 is a ανβ6 integrin ligand.
  • HY-P1654A
    A20FMDV2-Cys
    		Ligand
    A20FMDV2-Cys is a cysteine-containing 20-mer peptide that targets integrin αvβ6 with high affinity. A20FMDV2-Cys can be used for targeted liposome modification to enhance liver and bile duct targeting. A20FMDV2-Cys is applicable for research in drug delivery.
  • HY-185467
    Tris-ανβ6 integrin ligand-1
    		Ligand
    Tris-ανβ6 integrin ligand-1 (the ligand part of Compound 150) is a Tris-ανβ6 integrin ligand.
  • HY-P1897
    Fibronectin active fragment control
    		Ligand
    Fibronectin active fragment control is an active peptide fragment of fibronectin. Fibronectin is a glycoprotein interacting with integrins. Fibronectin active fragment control can be used as a control for Gly-Arg-Gly-Asp-Ser (HY-P0295).
  • HY-185470
    L123Z358
    		Ligand
    L123Z358 is a ligand of αvβ6 integrin. L123Z358 can be conjugated with siRNA to achieve targeted drug delivery to muscle tissue.