2. Peptides
  3. G-{d-Arg}-GDSP

G-{d-Arg}-GDSP is an RGD peptide analogue that binds to the adhesion receptor of integrins and inhibits cellular fibronectin attachment as well as osteoclast resorption.

For research use only. We do not sell to patients.

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G-{d-Arg}-GDSP Chemical Structure

G-{d-Arg}-GDSP Chemical Structure

CAS No. : 111844-21-4

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G-{d-Arg}-GDSP Related Antibodies

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Description

G-{d-Arg}-GDSP is an RGD peptide analogue that binds to the adhesion receptor of integrins and inhibits cellular fibronectin attachment as well as osteoclast resorption[1].

In Vitro

G-{d-Arg}-GDSP (17-850 μM, 10 days) significantly inhibits osteoclastic resorption at 170 μM in 17-day-old fetal mouse metacarpals and inhibits 45Ca release in osteoclast precursor-dependent bone organ culture[1].
G-{d-Arg}-GDSP (170 μM, 4 days) shows inhibition of anchorage of periosteal TRAP+ precursors to the mineralized matrix and subsequent osteoclast formation compared with the control group[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

G-{d-Arg}-GDSP Related Antibodies
Molecular Weight

587.58

Formula

C22H37N9O10
CAS No.
Sequence Shortening

G-{d-Arg}-GDSP
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References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

G-{d-Arg}-GDSP111844-21-4OthersRGD peptideadhesion receptorfibronectin attachmentosteoclast resorptioInhibitorinhibitorinhibit

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