Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
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Parasite Related Products (2477)
Related Products (2477)
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Related Compound Screening Libraries (1)
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Parasite Isoform Comparison
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3-Aminobutanoic acid (Standard)
0 ImagesCat. No.: HY-W008833RCAS No.: 541-48-03-Aminobutanoic acid is a β-amino acid. 3-Aminobutanoic acid can protect plant against a challenge infection with P. infestans. 3-Aminobutanoic acid has various levels of susceptibility for the pathogen.
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Chaparrinone
0 ImagesCat. No.: HY-N12151CAS No.: 22611-34-3Chaparrinone is a quassinoid that can be isolated from the root of Eurycoma harmandiana. Chaparrinone has antimalarial and cytotoxic activities against Plasmodium falciparum and P-388 cells (IC50: 0.037 and 0.34 μg/mL respectively).
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Paromomycin
0 ImagesParomomycin (Aminosidine) is an orally active broad-spectrum aminoglycoside aminocyclitol. Paromomycin is produced by Streptomyces riomosus var. Paromomycinus. Paromomycin binding induces local conformational changes in the 16S rRNA A-site. Paromomycin exhibits inhibitory activity against C. parvum. Paromomycin can be used in research related to leishmaniasis, amoebiasis and cryptosporidiosis.
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Erythrinasinate B
0 ImagesCat. No.: HY-N3160CAS No.: 101959-37-9Synonyms: Octacosyl (E)-ferulateOctacosyl (E)-ferulate (Erythrinasinate B) (Compound 1) is an antiplasmodial compound. Octacosyl (E)-ferulate can be isolated from Erythrina.
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Proguanil (Standard)
0 ImagesProguanil (Standard) is the analytical standard of Proguanil. This product is intended for research and analytical applications. Proguanil, an antimalarial proagent, is metabolized to the active metabolite Cycloguanil (HY-12784). Proguanil is a dihydrofolate reductase (DHFR) inhibitor.
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Floxacrine
0 ImagesCat. No.: HY-123314CAS No.: 53966-34-0Synonyms: HOE-991Floxacrine (HOE-991) is a dihydroacridinedione derivative with antimalarial activity. Floxacrine can be used to study its activity against different Plasmodium species.
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Isazofos
0 ImagesCat. No.: HY-W341259CAS No.: 42509-80-8Isazofos is a broad-spectrum organophosphate insecticide-nematicide that controls numerous pests of turf, such as nematode Radopholus similis. Isazofos is also effective in the control of rice gall midge.
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SLU-10906
0 ImagesCat. No.: HY-170777CAS No.: 3065121-94-7
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Closantel sodium (Standard)
0 ImagesClosantel (sodium) (Standard) is the analytical standard of Closantel (sodium). This product is intended for research and analytical applications. Closantel sodium is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel sodium is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel sodium inhibits the O. volvulus L3 to L4 molt of developing.
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Chloroquinoxaline sulfonamide (Standard)
0 ImagesChloroquinoxaline sulfonamide (Standard) is the analytical standard of Chloroquinoxaline sulfonamide. This product is intended for research and analytical applications. Chloroquinoxaline sulfonamide (Chloroquinoxaline), a structural analogue of sulfaquinoxaline, is a topoisomerase II alpha/beta poison. Chloroquinoxaline sulfonamide is used to control coccidiosis in poultry, rabbit, sheep, and cattle. Antitumor activity.
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Niranthin (Standard)
0 ImagesCat. No.: HY-N6054RCAS No.: 50656-77-4Niranthin (Standard) is the analytical standard of Niranthin. This product is intended for research and analytical applications. Niranthin, a lignan with a wide spectrum of pharmacological activities. Niranthin is a potent and non-competitive inhibitor of heterodimeric type IB topoisomerase of L. donovani. Niranthin can be used for the research of drug-resistant leishmaniasis research.
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Lupeol acetate (Standard)
0 ImagesCat. No.: HY-126114RCAS No.: 1617-68-1Lupeol acetate (Standard) is the analytical standard of Lupeol acetate. This product is intended for research and analytical applications. Lupeol acetate is a derivative of Lupeol. Lupeol acetate is an anti-inflammatory, antibacterial, anti-trypanosomic and anticancer agent with oral activity. Lupeol acetate significantly improves the symptoms of rheumatoid arthritis by down-regulating the expression of inflammatory cytokines and osteoclast production. Lupeol acetate inhibits spermatogenesis in male rats and eventually led to infertility.
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Pentadecane (Standard)
0 ImagesPentadecane (Standard) is the analytical standard of Pentadecane (HY-N7926). This product is intended for research and analytical applications. Pentadecane is an orally active natural plant volatile alkane with anti-inflammatory, analgesic, antipyretic and anti-leishmanial activities. Pentadecane presents IC50 values of 65.3 μM, 60.5 μM and 194.8 μM against Leishmania infantum promastigotes, amastigotes and intracellular amastigotes, respectively. Pentadecane downregulates the mRNA expression of TNF-α and IL-12 and inhibits the release of inflammatory mediators. Pentadecane arrests the cell cycle of Leishmania infantum and induces apoptosis. Pentadecane can be applied to the research of inflammation and leishmaniasis.
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Atherosperminine hydrochloride
0 ImagesCat. No.: HY-N7648ACAS No.: 54749-97-2Synonyms: Atherospermine hydrochlorideAtherosperminine (Atherospermine) hydrochloride is a phosphodiesterase inhibitor. Atherosperminine hydrochloride inhibits growth of chloroquine-resistant Plasmodium falciparum. Atherosperminine hydrochloride scavenges DPPH free radicals, exhibits ferric reducing power, and chelates metal ions. Atherosperminine hydrochloride can be used for the research of malaria.
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Lemidosul
0 ImagesCat. No.: HY-160985CAS No.: 88041-40-1Lemidosul is an anti-trypanosomiasis compound that can be further optimized for its performance as an anti-trypanosomiasis drug by means of a computer-aided drug design (CADD) approach.
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Isopentaquine
0 ImagesIsopentaquine is an orally active antimalarial agent. Isopentaquine induces mild morphological changes in the exoerythrocytic stage of Plasmodium fallax, with a ED50 of 6.7 mg/L. Isopentaquine causes degenerative changes in the development of Plasmodium oocysts in infected mosquitoes. Isopentaquine reduces the infectivity of Plasmodium falciparum gametocytes. Isopentaquine impairs sympathetic cardiovascular reflexes. Isopentaquine decreases the recurrence rate and total disease duration of Plasmodium vivax infection. Isopentaquine can be used in malaria-related research.
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Atherosperminine
0 ImagesAtherosperminine (Atherospermine) is a phosphodiesterase inhibitor. Atherosperminine inhibits growth of chloroquine-resistant Plasmodium falciparum. Atherosperminine scavenges DPPH free radicals, exhibits ferric reducing power, and chelates metal ions. Atherosperminine can be used for the research of malaria.
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Kikumycin A
0 ImagesCat. No.: HY-124431CAS No.: 37913-77-2Kikumycin A is an antibiotic, which can be generated from Streptomyces. Kikumycin A exhibits antibacterial activity against Gram-positive and Gram-negative bacteria. Kikumycin A exhibits antitrichomonal activity, with MIC of 25 μg/mL for Trichomonas foetus.
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Rubiadin (Standard)
0 ImagesRubiadin (Standard) is the analytical standard of Rubiadin (HY-N0444). This product is intended for research and analytical applications. Rubiadin is an orally active free radical scavenger that inhibits the activation of the NF-κB pathway. Rubiadin inhibits osteoclast formation, bone resorption, lipid peroxidation, HBV DNA replication and cancer cell proliferation; reduces pro-inflammatory cytokine levels; induces cancer cell apoptosis; and possesses antifungal, antimalarial, antibacterial and anticonvulsant activities. Rubiadin can be used in the research of osteoporosis, acute inflammation, chronic inflammation, carbon tetrachloride-induced liver injury, Alzheimer's disease, breast cancer, iron overload disorders, hepatitis B virus infection, colon cancer, liver cancer, T-lymphocytic leukemia, cervical cancer, diabetic nephropathy, epileptic seizures, fungal infections, malaria and bacterial infections.
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HDAC1-IN-15
0 ImagesCat. No.: HY-187346CAS No.: 3055432-86-2HDAC1-IN-15 is a HDAC1 inhibitor with activity against hHDAC1, PfHDAC1 and HDAC8. HDAC1-IN-15 inhibits the proliferation of asexual blood-stage Plasmodium falciparum and reduces the survival rate of stage IV-V gametocytes of Plasmodium falciparum. HDAC1-IN-15 is applicable to malaria-related research.
