2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B0537R
    Pentamidine (Standard)
    		Inhibitor
    Pentamidine (Standard) is the analytical standard of Pentamidine. This product is intended for research and analytical applications. Pentamidine (MP-601205) is an antimicrobial agent and interferes with DNA biosynthetics. Pentamidine inhibits parasite Leishmania infantum with an IC50 of 2.5 μM. Pentamidine is a potent and selective protein tyrosine phosphatases (PTPases) and phosphatase of regenerating liver (PRL) inhibitor. Pentamidine has the potential for Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia treatment. Antitumor and antibacterial activities.
    Pentamidine (Standard)
  • HY-B0497CR
    Niclosamide olamine (Standard)
    		Inhibitor
    Crocin (Standard) is the analytical standard of Crocin. This product is intended for research and analytical applications. Crocin (Crocin I) is an orally active natural product that can be isolated from the stigma of Crocus sativus. Crocin inhibits tumor cell proliferation and promotes apoptosis through JAK pathway. Crocin has anti-inflammatory, antioxidant and antitumor activities .
    Niclosamide olamine (Standard)
  • HY-B0508R
    Ornidazole (Standard)
    		Inhibitor
    Ornidazole (Standard) is the analytical standard of Ornidazole. This product is intended for research and analytical applications. Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease.
    Ornidazole (Standard)
  • HY-171956
    Carmaphycin-17
    		Inhibitor
    Carmaphycin-17 (CP-17) is a selective 20S proteasome inhibitor with an EC50 of 217 ?nM. Carmaphycin-17 has potent antimicrobial activity against Trichomonas vaginalis. Carmaphycin-17 overcomes Metronidazole (HY-B0318) resistance and significantly reduces parasite burden upon topical treatment without any apparent adverse effects in vaginal trichomonad infection mice model. Carmaphycin-17 can be used for sexually transmitted disease like trichomoniasis research.
    Carmaphycin-17
  • HY-W742094
    Cycotiamine
    		Inhibitor
    Cycotiamine is an S-acylated thiamine derivative with antiplasmodial activity. Cycotiamine inhibits the proliferation of Plasmodium falciparum and Plasmodium knowlesi. Cycotiamine can be used in malaria-related research.
    Cycotiamine
  • HY-B0217R
    Nitazoxanide (Standard)
    		Inhibitor
    Nitazoxanide (Standard) is the analytical standard of Nitazoxanide. This product is intended for research and analytical applications. Nitazoxanide (NTZ), an anthelmintic agent, exhibits a broad spectrum of activities against a wide variety of helminths, protozoa, and enteric bacteria infecting animals and humans. Nitazoxanide inhibits Giardia lamblia trophozoite proliferation in axenic culture with an IC50 of 2.4 μM. Nitazoxanide can be used for the research of parasitic gastroenteritis. Nitazoxanide shows anti-Japanese encephalitis virus (JEV) activity in a mouse model.
    Nitazoxanide (Standard)
  • HY-169233
    MED6-189
    		Inhibitor
    MED6-189, a kalihinol analog, disrupts apicoplast function and vesicular trafficking in P. falciparum malaria (IC50 < 50 nM). MED6-189 targets the apicoplast, a nonphotosynthetic plastid found in most Apicomplexa parasites that is crucial for the synthesis of isoprenoids.
    MED6-189
  • HY-N13988
    Abierixin
    		Inhibitor
    Abierixin has good anti-coccidial activity and weak antibacterial and ionophore activity.
    Abierixin
  • HY-12936
    DDD100097
    		Inhibitor
    DDD100097 is a potent acyltransferase (TbNMT) inhibitor with an IC50 value of 2 nM. DDD100097 can significantly improve blood-brain barrier permeability. DDD100097 can be used in the study of African trypanosomiasis.
    DDD100097
  • HY-127028
    Tripynadine
    		Inhibitor
    Tripynadine is an anti-malarial compound with oral activity.
    Tripynadine
  • HY-175979
    HAT-IN-9
    		Inhibitor
    HAT-IN-9 (Compound 3F) is a selective proliferation inhibitor targeting Trypanosoma brucei. HAT-IN-9 inhibits the proliferation and division of Trypanosoma brucei. HAT-IN-9 is promising for research of African trypanosomiasis (HAT, i.e., sleeping sickness).
    HAT-IN-9
  • HY-W104379S
    Arprinocid-15N3
    Arprinocid-15N3 is 15N3-labeled Arprinocid (HY-W104379). Arprinocid is a purine analog with activity against murine Toxoplasma gondii.
    Arprinocid-<sup>15</sup>N<sub>3</sub>
  • HY-B1244R
    Dimetridazole (Standard)
    		Inhibitor
    Dimetridazole (Standard) is the analytical standard of Dimetridazole (HY-B1244). This product is intended for research and analytical applications. Dimetridazole is a nitroimidazole antibiotic. Dimetridazole inhibits protein synthesis in cultures of Campylobacter jejuni. Dimetridazole is genotoxic. Dimetridazole can be used in the research of protozoal and bacterial infections.
    Dimetridazole (Standard)
  • HY-125084
    NEU617
    		Inhibitor
    NEU617 is an anti-parasite agent. NEU617 inhibits the proliferation for the HAT (human African trypanosomiasis) pathogen (EC50: 42 nM for Trypanosoma brucei, 1.8 μM for T. cruzi). NEU617 is a derivative of Lapatinib (HY-50898).
    NEU617
  • HY-B1548R
    Benznidazole (Standard)
    		Inhibitor
    Benznidazole (Standard) is the analytical standard of Benznidazole. This product is intended for research and analytical applications. Benznidazole (Ro 07-1051) is an antiparasitic medication, with an IC50 of 20.35 μM for Colombian T. cruzi strains, and has been used in the treatment of Chagas disease.
    Benznidazole (Standard)
  • HY-W046346
    D44
    		Inhibitor
    D44 is a Plasmodium FKBP35 inhibitor that selectively inhibits the FKBD35 PPIase activity, with PPIase IC50 values of 132 nM and 125 nM for Plasmodium falciparum and Plasmodium vivax, respectively. D44 exhibits antiplasmodium activity and can be used in research related to infectious diseases.
    D44
  • HY-121273
    Diclofop
    		Inhibitor
    Diclofop (Dichlorfop acid) is an acetyl-CoA carboxylase (ACC) inhibitor. Diclofop is also the major metabolite of the herbicide Diclofop-methyl (HY-136367). Diclofop exhibits antimalarial activity with an IC50 of 210 μM against P. falciparum.
    Diclofop
  • HY-17596R
    Closantel (Standard)
    		Inhibitor
    Closantel (Standard) is the analytical standard of Closantel. This product is intended for research and analytical applications. Closantel is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel inhibits the O. volvulus L3 to L4 molt of developing.
    Closantel (Standard)
  • HY-133093
    Murayaquinone
    		Inhibitor
    Murayaquinone (PKF118-774) is a β-catenin/Tcf4 complex inhibitor with an IC50 of 2.4 μM. Murayaquinone is a nematicidal agent found in Streptomyces sp. AN140557.
    Murayaquinone
  • HY-78131CR
    Ibuprofen sodium (Standard)
    Ibuprofen (sodium) (Standard) is the analytical standard of Ibuprofen (sodium). This product is intended for research and analytical applications. Ibuprofen ((±)-Ibuprofen) sodium is an orally active, selective COX-1 inhibitor with an IC50 value of 13 μM. Ibuprofen sodium inhibits cell proliferation, angiogenesis, and induces cell apoptosis. Ibuprofen sodium is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. Ibuprofen sodium can be used in the research of pain, swelling, inflammation, infection, immunology, cancers.
    Ibuprofen sodium (Standard)
Parasite Isoform Comparison

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