Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
All Product Categories
-
Isotope-Labeled Compounds Related Products (11099)
Related Products (11099)
-
Evogliptin-d9
0 ImagesCat. No.: HY-117985SSynonyms: DA-1229-d9Evogliptin-d9 (DA-1229-d9) is deuterium labeled Evogliptin. Evogliptin (DA-1229) is an orally active DPP4 inhibitor with significant and sustained hypoglycaemic effects in mouse models. Evogliptin also inhibits the production of inflammatory and fibrotic signals in hepatocytes by inducing autophagy. Evogliptin can be used in studies of type 2 diabetes, osteoporosis, renal impairment and chronic liver inflammation.
-
9-Phenylcarbazole-d13
0 ImagesCat. No.: HY-33672SCAS No.: 2847910-31-8Synonyms: N-Phenylcarbazole-d139-Phenylcarbazole-d13 (N-Phenylcarbazole-d13) is the deuterium labeled 9-Phenylcarbazole (HY-33672).
-
10α-Methoxy-9,10-dihydrolysergol-d3
0 ImagesCat. No.: HY-W654262Synonyms: ((6aR,9R,10aS)-10a-Methoxy-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methanol (Nicergoline Impurity)-d310α-Methoxy-9,10-dihydrolysergol-d3 is deuterium labeled ((6aR,9R,10aS)-10a-Methoxy-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methanol (Nicergoline Impurity).
-
Elagolix-d6 sodium
0 ImagesCat. No.: HY-W751574Synonyms: NBI-56418-d6 sodiumElagolix-d6 (sodium) (NBI-56418-d6 (sodium)) is deuterium labeled Elagolix sodium. Elagolix sodium is a highly effective, selective, oral-active, short-term, non-peptide gonadotropin-releasing hormone receptor (GnRH receptor) antagonist (KD = 54 pM) and NFAT inhibitor, which can be used to study pain related to endometriosis. .
-
Thiamphenicol-d3-1
0 ImagesSynonyms: Thiophenicol-d3-1; Dextrosulphenidol-d3-1Thiamphenicol-d3-1 (Thiophenicol-d3-1; Dextrosulphenidol-d3-1) is the deuterium-labeled Thiamphenicol (HY-B0479). Thiamphenicol (Thiophenicol), a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria).
-
Maltose monohydrate-13C
0 ImagesCat. No.: HY-N2024AS2Maltose monohydrate-13C is the 13C labeled isotope of Maltose monohydrate. Maltose monohydrate is a disaccharide composed of two glucose molecules linked together. Maltose monohydrate is an endogenous metabolic product in plants, yeast, or bacteria, and it participates in carbon source storage and metabolism. Maltose monohydrate is a key core metabolite and main transport form in the temporary starch degradation, carbon output, and subsequent sucrose synthesis metabolism of the night chloroplast. In X. dendrorhous, maltose can act as a sugar donor and is converted into isomaltulose by α-glucosidase. Maltose monohydrate can act as a osmotic agent, supporting continuous capillary ultrafiltration and preventing severe metabolic disorders.
-
Maresin 2-d5
0 ImagesCat. No.: HY-119684SMaresin 2-d5 is the d5-labeled Maresin 2 (HY-119684). Maresin 2 is an anti-inflammatory and pro-resolving mediator. Maresin 2 drives intestinal epithelial cell migration by activating the focal cell-matrix adhesion signaling pathway in primary human intestinal epithelial cells, thereby promoting mucosal wound repair. Maresin 2 alleviates nociceptive and anxiety-like behaviors in rats with type 1 diabetes by inhibiting IL-1β in the spinal cord and prefrontal cortex. Maresin 2 attenuates allergic airway inflammation in mice by inhibiting the activation of the NLRP3 inflammasome, Th2-type immune responses, and oxidative stress. Maresin 2 inhibits inflammatory and neuropathic trigeminal neuralgia and reduces neuronal activation in the trigeminal ganglion. Maresin 2 promotes inflammation resolution and mucosal repair after DSS-induced colitis or biopsy-induced colonic mucosal injury.
-
(R)-Hydroxytolterodine-d14
0 ImagesCat. No.: HY-76569S1CAS No.: 1191280-58-6Synonyms: PNU-200577-d14; 5-Hydroxymethyl Tolterodine-d14(R)-Hydroxytolterodine-d14 is deuterated labeled Desfesoterodine (HY-76569). Desfesoterodine (PNU-200577) is a potent and selective muscarinic receptor (mAChR) antagonist with a KB and a pA2 of 0.84 nM and 9.14, respectively. Desfesoterodine is a major pharmacologically active metabolite of Tolterodine (PNU-200583; HY-A0024) and Fesoterodine (HY-70053). Desfesoterodine improves cerebral infarction induced detrusor overactivity in rats.
-
1,2,3,4-Tetrahydroquinoxaline-d4
0 ImagesCat. No.: HY-W012652SCAS No.: 1822872-69-4Synonyms: Quinoxaline, 1,2,3,4-tetrahydro-d41,2,3,4-Tetrahydroquinoxaline-d4 (Quinoxaline, 1,2,3,4-tetrahydro-d4) is the deuterium labeled 1,2,3,4-Tetrahydroquinoxaline.
-
Desmethylcitalopram-d4 hydrochloride
0 ImagesCat. No.: HY-113739S1Synonyms: DCIT-d4 hydrochlorideDesmethylcitalopram-d4 hydrochloride is deuterated labeled Desmethylcitalopram hydrochloride (HY-113739). Desmethylcitalopram (DCIT) hydrochloride is the active metabolite of Citalopram (HY-121203). Desmethylcitalopram has antidepressant effects. Desmethylcitalopram also inhibits cytochrome P450-2D6, -2C19 with IC50s of 39.5 and 53.5 μM.
-
4-Fluorobenzoic acid-13C,d4
0 ImagesCat. No.: HY-W013677S1CAS No.: 285977-82-44-Fluorobenzoic acid-13C,d4 is the 13C- and deuterium labeled 4-Fluorobenzoic acid (HY-W013677). 4-Fluorobenzoic acid is a drug intermediate that can be used to synthesize a series of hydrazone derivatives with antituberculosis activity and Schiff bases with DPPH radical scavenging activity.
-
Verlukast-d6
0 ImagesCat. No.: HY-76511SCAS No.: 153698-86-3Synonyms: MK-679-d6; L 668019-d6Verlukast-d6 is a deuterium labeled Verlukast. Verlukast is a potent, selective, and orally active antagonist of leukotriene receptor. Verlukast has the potential for the research of asthma.
-
BEA 2180 alcohol-d3
0 ImagesCat. No.: HY-166886SBEA 2180 alcohol-d3 is deuterium labeled BEA 2180 alcohol.
-
2,3-Pentanedione-13C2
0 ImagesCat. No.: HY-W012998S1CAS No.: 3028870-57-42,3-Pentanedione-13C2 is 13C labeled 2,3-Pentanedione (HY-W012998). 2,3-Pentanedione is a common constituent of synthetic flavorings and is used to impart a butter, strawberry, caramel, fruit, rum, or cheese flavor in beverages, ice cream, candy, baked goods, gelatins, and puddings. 2,3-Pentanedione also occurs naturally as a fermentation product in beer, wine, and yogurt and is releasedduring roasting of coffee beans.
-
Isotretinoin-d5
0 ImagesCat. No.: HY-15127SIsotretinoin-d5 is the deuterium labeled Isotretinoin. Isotretinoin is an orally active vitamin A derivative and is often be used for the research of severe acne. Isotretinoin also shows anticancer activity.
-
Desmetryn-d3
0 ImagesCat. No.: HY-113543SDesmetryn-d3 is deuterium labeled Desmetryn.
-
1,2,3,4-Hydroquinoline-d2
0 ImagesCat. No.: HY-Y0659SCAS No.: 20668-18-2Synonyms: 1,2,3,4-Tetrahydroquinoline-d2; 3,4-Dihydro-2H-quinoline-d21,2,3,4-Hydroquinoline-d2 (1,2,3,4-Tetrahydroquinoline-d2) is the deuterium labeled 1,2,3,4-Hydroquinoline.
-
Tetrabromobisphenol A-d6
0 ImagesCat. No.: HY-W769576Tetrabromobisphenol A-d6 is deuterium labeled 4,4'-(Propane-2,2-diyl)bis(2,6-dibromophenol).
-
(Rac)-Norepinephrine-d3 formate
0 ImagesCat. No.: HY-13715S(Rac)-Norepinephrine-d3 (formate) is deuterium labeled Norepinephrine. Norepinephrine (Levarterenol; L-Noradrenaline) is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α1, α2, β1 receptors.
-
(±)EP-0226A-d4
0 ImagesCat. No.: HY-179245S(±)EP-0226A-d4 is the deuterium labeled (±)EP-0226A.
