Desmethylcitalopram hydrochloride
Based on 1 Customer Validation
Desmethylcitalopram (DCIT) hydrochloride is the active metabolite of Citalopram (HY-121203). Desmethylcitalopram has antidepressant effects. Desmethylcitalopram also inhibits cytochrome P450-2D6, -2C19 with IC50s of 39.5 and 53.5 μM.
For research use only. We do not sell to patients.
- Purity: 99.87%
- CAS No.: 97743-99-2
- Formula: C19H20ClFN2O
- Molecular Weight:346.83
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Storage:
Store at room temperature, keep dry and cool.
In solvent -80°C, 1 year , -20°C, 6 months
Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 97743-99-2
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Appearance Solid
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Molecular Weight 346.83
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Formula C19H20ClFN2O
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Color White to off-white
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SMILES
CNCCCC1(OCC2=CC(C#N)=CC=C21)C3=CC=C(C=C3)F.Cl
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Synonyms
DCIT hydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature, keep dry and cool
In solvent -80°C 1 year -20°C 6 months
Solvent & Solubility
DMSO : 100 mg/mL (288.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8833 mL | 14.4163 mL | 28.8326 mL | 72.0814 mL |
| 5 mM | 0.5767 mL | 2.8833 mL | 5.7665 mL | 14.4163 mL | |
| 10 mM | 0.2883 mL | 1.4416 mL | 2.8833 mL | 7.2081 mL | |
| 15 mM | 0.1922 mL | 0.9611 mL | 1.9222 mL | 4.8054 mL | |
| 20 mM | 0.1442 mL | 0.7208 mL | 1.4416 mL | 3.6041 mL | |
| 25 mM | 0.1153 mL | 0.5767 mL | 1.1533 mL | 2.8833 mL | |
| 30 mM | 0.0961 mL | 0.4805 mL | 0.9611 mL | 2.4027 mL | |
| 40 mM | 0.0721 mL | 0.3604 mL | 0.7208 mL | 1.8020 mL | |
| 50 mM | 0.0577 mL | 0.2883 mL | 0.5767 mL | 1.4416 mL | |
| 60 mM | 0.0481 mL | 0.2403 mL | 0.4805 mL | 1.2014 mL | |
| 80 mM | 0.0360 mL | 0.1802 mL | 0.3604 mL | 0.9010 mL | |
| 100 mM | 0.0288 mL | 0.1442 mL | 0.2883 mL | 0.7208 mL |