Ac-LEVD-CHO TFA
Based on 1 publication(s) in Google Scholar
Ac-LEVD-CHO (TFA) is an inhibitor of caspase-4. Ac-LEVD-CHO (TFA) can inhibit the expression and secretion of IL-1α expression as well as the activation of caspase-4 induced by the T. denticola periodontal pathogen surface protein Td92 in human gingival fibroblasts. Ac-LEVD-CHO (TFA) can also reduce the apoptosis due to the expression of the dominant negative adenoviral RNA-dependent protein kinase in A549 and PC3 cancer cell lines.
For research use only. We do not sell to patients.
- Formula: C24H37F3N4O11
- Molecular Weight:614.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Publications Citing Use of MedChemExpress (MCE) Ac-LEVD-CHO TFA
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Biological Activity
Chemical Information
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Molecular Weight 614.57
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Formula C24H37F3N4O11
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Sequence
Ac-Leu-Glu-Val-Asp-CHO
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Sequence Shortening
Ac-LEVD-CHO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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PLoS Pathog
African swine fever virus pEP364R acts as an important inflammatory-inducing factor to activate NLRP3 inflammasome-mediated pyroptosis by regulating DDX3X. [Abstract]2026 Feb 25;22(2):e1013874. PMID: 41739885
Purity & Documentation
References
[1]. Jun, H. K., et al., (2018). Caspase-4 activation by a bacterial surface protein is mediated by cathepsin G in human gingival fibroblasts. Cell death and differentiation, 25(2), 380–391. [Content Brief]
[2]. Pataer, A., et al., (2009). Inhibition of RNA-dependent protein kinase (PKR) leads to cancer cell death and increases chemosensitivity. Cancer biology & therapy, 8(3), 245–252. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ac-LEVD-CHO TFA Related Classifications
HY-136727A Related Classifications
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